ID   K2C3_BOVIN              Reviewed;         182 AA.
AC   P04261;
DT   20-MAR-1987, integrated into UniProtKB/Swiss-Prot.
DT   20-MAR-1987, sequence version 1.
DT   03-AUG-2022, entry version 102.
DE   RecName: Full=Keratin, type II cytoskeletal 60 kDa, component III;
DE   Flags: Fragment;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=6084625; DOI=10.1111/j.1432-0436.1984.tb00278.x;
RA   Jorcano J.L., Franz J.K., Franke W.W.;
RT   "Amino acid sequence diversity between bovine epidermal cytokeratin
RT   polypeptides of the basic (type II) subfamily as determined from cDNA
RT   clones.";
RL   Differentiation 28:155-163(1984).
CC   -!- SUBUNIT: Heterotetramer of two type I and two type II keratins.
CC   -!- MISCELLANEOUS: There are two types of cytoskeletal and microfibrillar
CC       keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).
CC   -!- SIMILARITY: Belongs to the intermediate filament family.
CC       {ECO:0000255|PROSITE-ProRule:PRU01188}.
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DR   EMBL; K03535; AAA30602.1; -; mRNA.
DR   PIR; A02947; A02947.
DR   AlphaFoldDB; P04261; -.
DR   SMR; P04261; -.
DR   PeptideAtlas; P04261; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0045095; C:keratin filament; IBA:GO_Central.
DR   GO; GO:0030280; F:structural constituent of skin epidermis; IBA:GO_Central.
DR   GO; GO:0045109; P:intermediate filament organization; IBA:GO_Central.
DR   GO; GO:0031424; P:keratinization; IBA:GO_Central.
DR   InterPro; IPR018039; IF_conserved.
DR   InterPro; IPR039008; IF_rod_dom.
DR   Pfam; PF00038; Filament; 1.
DR   PROSITE; PS00226; IF_ROD_1; 1.
DR   PROSITE; PS51842; IF_ROD_2; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Intermediate filament; Keratin; Reference proteome.
FT   CHAIN           <1..182
FT                   /note="Keratin, type II cytoskeletal 60 kDa, component III"
FT                   /id="PRO_0000063730"
FT   DOMAIN          <1..63
FT                   /note="IF rod"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01188"
FT   REGION          <1..63
FT                   /note="Coil 2"
FT   REGION          63..182
FT                   /note="Tail"
FT   REGION          157..182
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            1
FT                   /note="Stutter"
FT   NON_TER         1
SQ   SEQUENCE   182 AA;  17560 MW;  C263102147632F66 CRC64;
     ERGELALKDA RSKLADVEDA LQKAKQDMAR LLREYQELMN TKLALDVEIA TYRKLLEGEE
     CRLSGEGVGP VNISVVTNTV SSGYGGGSGF GGGLGGGLGG GLGGGLGGGL GGGLGSGLGG
     GGSSSFYSSS SGGVGLGGGL SVGGSGFSAS SGRSLGFGSG GGSSSSVKFV STTSSSRKSF
     KS