KAB9_OLDAF
ID KAB9_OLDAF Reviewed; 31 AA.
AC P85127;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 10-JUL-2007, sequence version 1.
DT 25-MAY-2022, entry version 27.
DE RecName: Full=Kalata-B9;
OS Oldenlandia affinis.
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC asterids; lamiids; Gentianales; Rubiaceae; Rubioideae; Spermacoceae;
OC Hedyotis-Oldenlandia complex; Oldenlandia.
OX NCBI_TaxID=60225;
RN [1] {ECO:0000305}
RP PROTEIN SEQUENCE, AND MASS SPECTROMETRY.
RX PubMed=17534989; DOI=10.1002/cbic.200700097;
RA Plan M.R.R., Goeransson U., Clark R.J., Daly N.L., Colgrave M.L.,
RA Craik D.J.;
RT "The cyclotide fingerprint in Oldenlandia affinis: elucidation of
RT chemically modified, linear and novel macrocyclic peptides.";
RL ChemBioChem 8:1001-1011(2007).
CC -!- FUNCTION: Probably participates in a plant defense mechanism.
CC {ECO:0000305}.
CC -!- DOMAIN: The presence of a 'disulfide through disulfide knot'
CC structurally defines this protein as a knottin.
CC {ECO:0000250|UniProtKB:P85175}.
CC -!- PTM: This peptide occurs in both cyclic and linear forms.
CC {ECO:0000269|PubMed:17534989}.
CC -!- MASS SPECTROMETRY: Mass=3272.8; Method=Electrospray; Note=Cyclic form.;
CC Evidence={ECO:0000269|PubMed:17534989};
CC -!- MASS SPECTROMETRY: Mass=3290.8; Method=Electrospray; Note=Linear form.;
CC Evidence={ECO:0000269|PubMed:17534989};
CC -!- SIMILARITY: Belongs to the cyclotide family. Bracelet subfamily.
CC {ECO:0000269|PubMed:17534989}.
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DR AlphaFoldDB; P85127; -.
DR SMR; P85127; -.
DR GO; GO:0006952; P:defense response; IEA:UniProtKB-KW.
DR InterPro; IPR005535; Cyclotide.
DR InterPro; IPR012324; Cyclotide_moebius_CS.
DR InterPro; IPR036146; Cyclotide_sf.
DR Pfam; PF03784; Cyclotide; 1.
DR SUPFAM; SSF57038; SSF57038; 1.
DR PROSITE; PS60009; CYCLOTIDE_MOEBIUS; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Disulfide bond; Knottin; Plant defense.
FT PEPTIDE 1..31
FT /note="Kalata-B9"
FT /evidence="ECO:0000269|PubMed:17534989"
FT /id="PRO_0000294956"
FT DISULFID 6..20
FT /evidence="ECO:0000250|UniProtKB:P85175"
FT DISULFID 10..22
FT /evidence="ECO:0000250|UniProtKB:P85175"
FT DISULFID 15..28
FT /evidence="ECO:0000250|UniProtKB:P85175"
FT CROSSLNK 1..31
FT /note="Cyclopeptide (Gly-Asp)"
FT /evidence="ECO:0000269|PubMed:17534989"
SQ SEQUENCE 31 AA; 3297 MW; 371C424EB69BF6FA CRC64;
GSVFNCGETC VLGTCYTPGC TCNTYRVCTK D