ID   KAC4_RABIT              Reviewed;         103 AA.
AC   P01840;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Ig kappa-b4 chain C region;
OS   Oryctolagus cuniculus (Rabbit).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX   NCBI_TaxID=9986;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6412231; DOI=10.1073/pnas.80.18.5709;
RA   Emorine L., Dreher K.L., Kindt T.J., Max E.E.;
RT   "Rabbit immunoglobulin kappa genes: structure of a germline b4 allotype J-C
RT   locus and evidence for several b4-related sequences in the rabbit genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 80:5709-5713(1983).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6795636; DOI=10.1073/pnas.78.9.5802;
RA   Heidmann O., Auffray C., Cazenave P.-A., Rougeon F.;
RT   "Nucleotide sequence of constant and 3' untranslated regions of a kappa
RT   immunoglobulin light chain mRNA of a homozygous b4 rabbit.";
RL   Proc. Natl. Acad. Sci. U.S.A. 78:5802-5806(1981).
RN   [3]
RP   PROTEIN SEQUENCE.
RX   PubMed=1091650; DOI=10.1016/s0021-9258(19)41512-3;
RA   Chen K.C.S., Kindt T.J., Krause R.M.;
RT   "Primary structure of the L chain from a rabbit homogeneous antibody to
RT   streptococcal carbohydrate. II. Sequence determination of peptides from
RT   tryptic and peptic digests.";
RL   J. Biol. Chem. 250:3289-3296(1975).
CC   -!- MISCELLANEOUS: This chain was obtained from antibody to the specific
CC       carbohydrate of group C Streptococci and was isolated from the serum of
CC       a single rabbit.
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DR   EMBL; X00231; CAA25051.1; -; Genomic_DNA.
DR   PIR; A93971; K4RB.
DR   PDB; 6DID; EM; 4.71 A; C/E/H=1-103.
DR   PDBsum; 6DID; -.
DR   AlphaFoldDB; P01840; -.
DR   SMR; P01840; -.
DR   PRIDE; P01840; -.
DR   Proteomes; UP000001811; Unplaced.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003597; Ig_C1-set.
DR   Pfam; PF07654; C1-set; 1.
DR   SMART; SM00407; IGc1; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Direct protein sequencing; Disulfide bond;
KW   Immunoglobulin domain; Reference proteome.
FT   CHAIN           <1..103
FT                   /note="Ig kappa-b4 chain C region"
FT                   /id="PRO_0000153599"
FT   DOMAIN          5..95
FT                   /note="Ig-like"
FT   DISULFID        26..85
FT   DISULFID        103
FT                   /note="Interchain (with a heavy chain)"
FT   CONFLICT        58
FT                   /note="N -> D (in Ref. 3; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   NON_TER         1
SQ   SEQUENCE   103 AA;  11043 MW;  5FC5ACC8B60E68DB CRC64;
     DPVAPTVLIF PPAADQVATG TVTIVCVANK YFPDVTVTWE VDGTTQTTGI ENSKTPQNSA
     DCTYNLSSTL TLTSTQYNSH KEYTCKVTQG TTSVVQSFNR GDC