ID   KACB_RABIT              Reviewed;         106 AA.
AC   P01839;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Ig kappa-b4 chain C region;
GN   Name=K-BAS;
OS   Oryctolagus cuniculus (Rabbit).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Lagomorpha; Leporidae; Oryctolagus.
OX   NCBI_TaxID=9986;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=Basilea;
RX   PubMed=11894960; DOI=10.1002/j.1460-2075.1983.tb01441.x;
RA   Heidmann O., Rougeon F.;
RT   "Multiplicity of constant kappa light chain genes in the rabbit genome: a
RT   b4b4 homozygous rabbit contains a kappa-bas gene.";
RL   EMBO J. 2:437-441(1983).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=3114714; DOI=10.1093/nar/15.15.6171;
RA   Mariame B., Akimenko M.-A., Rougeon F.;
RT   "Interallelic and intergenic conversion events could induce differential
RT   evolution of the two rabbit immunoglobulin kappa light chain genes.";
RL   Nucleic Acids Res. 15:6171-6179(1987).
CC   -!- MISCELLANEOUS: In Basilea rabbits, the major type of light chain is
CC       lambda. The kappa chain shown is a minor component. All other rabbit B
CC       allotypes have 'Cys-64'.
CC   -!- MISCELLANEOUS: In rabbits two Ig kappa light chain genes are present, C
CC       kappa 1 and C kappa 2 or K-BAS.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; V00885; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   EMBL; X05800; CAA29246.1; -; Genomic_DNA.
DR   PIR; A02121; K4RBBS.
DR   PIR; G20907; G20907.
DR   AlphaFoldDB; P01839; -.
DR   SMR; P01839; -.
DR   STRING; 9986.ENSOCUP00000019666; -.
DR   PRIDE; P01839; -.
DR   eggNOG; ENOG502RZ26; Eukaryota.
DR   InParanoid; P01839; -.
DR   Proteomes; UP000001811; Unplaced.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003597; Ig_C1-set.
DR   Pfam; PF07654; C1-set; 1.
DR   SMART; SM00407; IGc1; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
PE   4: Predicted;
KW   Disulfide bond; Immunoglobulin domain; Reference proteome.
FT   CHAIN           <1..106
FT                   /note="Ig kappa-b4 chain C region"
FT                   /id="PRO_0000153603"
FT   DOMAIN          6..99
FT                   /note="Ig-like"
FT   REGION          48..67
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        27..87
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   DISULFID        106
FT                   /note="Interchain (with a heavy chain)"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00114"
FT   NON_TER         1
SQ   SEQUENCE   106 AA;  11279 MW;  AF9B928DDA853849 CRC64;
     GDPVAPSVLL FPPSKEELTT GTATIVCVAN KFYPSDITVT WKVDGTTQQS GIENSKTPQS
     PEDNTYSLSS TLSLTSAQYN SHSVYTCEVV QGSASPIVQS FNRGDC