ID   KACB_RAT                Reviewed;         106 AA.
AC   P01835;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 103.
DE   RecName: Full=Ig kappa chain C region, B allele;
OS   Rattus norvegicus (Rat).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Rattus.
OX   NCBI_TaxID=10116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=Louvain;
RX   PubMed=6273908; DOI=10.1073/pnas.78.11.7064;
RA   Sheppard H.W., Gutman G.A.;
RT   "Allelic forms of rat kappa chain genes: evidence for strong selection at
RT   the level of nucleotide sequence.";
RL   Proc. Natl. Acad. Sci. U.S.A. 78:7064-7068(1981).
RN   [2]
RP   PROTEIN SEQUENCE (BENCE-JONES PROTEIN S211).
RX   PubMed=807630;
RA   Starace V., Querinjean P.;
RT   "The primary structure of a rat kappa Bence Jones protein: phylogenetic
RT   relationships of V- and C-region genes.";
RL   J. Immunol. 115:59-62(1975).
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DR   PIR; A93901; K1RTB.
DR   PDB; 1BFO; X-ray; 2.60 A; A/C/E/G=1-106.
DR   PDB; 1C5D; X-ray; 2.40 A; A/L=1-106.
DR   PDB; 1FN4; X-ray; 2.80 A; A/C=4-106.
DR   PDB; 1LK3; X-ray; 1.91 A; L/M=1-103.
DR   PDB; 4UAO; X-ray; 3.10 A; B=1-106.
DR   PDBsum; 1BFO; -.
DR   PDBsum; 1C5D; -.
DR   PDBsum; 1FN4; -.
DR   PDBsum; 1LK3; -.
DR   PDBsum; 4UAO; -.
DR   AlphaFoldDB; P01835; -.
DR   SMR; P01835; -.
DR   STRING; 10116.ENSRNOP00000066644; -.
DR   PaxDb; P01835; -.
DR   PRIDE; P01835; -.
DR   eggNOG; ENOG502RZ26; Eukaryota.
DR   HOGENOM; CLU_077975_3_0_1; -.
DR   InParanoid; P01835; -.
DR   EvolutionaryTrace; P01835; -.
DR   Proteomes; UP000002494; Unplaced.
DR   Genevisible; P01835; RN.
DR   GO; GO:0003823; F:antigen binding; IBA:GO_Central.
DR   GO; GO:0050776; P:regulation of immune response; IBA:GO_Central.
DR   Gene3D; 2.60.40.10; -; 1.
DR   InterPro; IPR007110; Ig-like_dom.
DR   InterPro; IPR036179; Ig-like_dom_sf.
DR   InterPro; IPR013783; Ig-like_fold.
DR   InterPro; IPR003006; Ig/MHC_CS.
DR   InterPro; IPR003597; Ig_C1-set.
DR   Pfam; PF07654; C1-set; 1.
DR   SMART; SM00407; IGc1; 1.
DR   SUPFAM; SSF48726; SSF48726; 1.
DR   PROSITE; PS50835; IG_LIKE; 1.
DR   PROSITE; PS00290; IG_MHC; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Direct protein sequencing; Disulfide bond;
KW   Immunoglobulin domain; Reference proteome.
FT   CHAIN           <1..106
FT                   /note="Ig kappa chain C region, B allele"
FT                   /id="PRO_0000153605"
FT   DOMAIN          5..102
FT                   /note="Ig-like"
FT   DISULFID        26..86
FT   DISULFID        106
FT                   /note="Interchain (with a heavy chain)"
FT   CONFLICT        2
FT                   /note="D -> N (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        30
FT                   /note="N -> K (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        48
FT                   /note="Missing (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        79
FT                   /note="E -> Q (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        87
FT                   /note="E -> Q (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        98
FT                   /note="V -> VW (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        100
FT                   /note="S -> N (in Ref. 2; AA sequence)"
FT                   /evidence="ECO:0000305"
FT   NON_TER         1
FT   STRAND          6..10
FT                   /evidence="ECO:0007829|PDB:1LK3"
FT   HELIX           14..17
FT                   /evidence="ECO:0007829|PDB:1LK3"
FT   TURN            18..20
FT                   /evidence="ECO:0007829|PDB:1LK3"
FT   STRAND          21..34
FT                   /evidence="ECO:0007829|PDB:1LK3"
FT   STRAND          37..42
FT                   /evidence="ECO:0007829|PDB:1LK3"
FT   STRAND          45..47
FT                   /evidence="ECO:0007829|PDB:1C5D"
FT   STRAND          51..55
FT                   /evidence="ECO:0007829|PDB:1LK3"
FT   TURN            60..62
FT                   /evidence="ECO:0007829|PDB:1LK3"
FT   STRAND          65..74
FT                   /evidence="ECO:0007829|PDB:1LK3"
FT   HELIX           75..79
FT                   /evidence="ECO:0007829|PDB:1LK3"
FT   STRAND          83..89
FT                   /evidence="ECO:0007829|PDB:1LK3"
FT   TURN            91..93
FT                   /evidence="ECO:0007829|PDB:1C5D"
FT   STRAND          94..96
FT                   /evidence="ECO:0007829|PDB:1BFO"
FT   STRAND          97..102
FT                   /evidence="ECO:0007829|PDB:1LK3"
SQ   SEQUENCE   106 AA;  11601 MW;  4CFA7CA820D1CA36 CRC64;
     ADAAPTVSIF PPSTEQLATG GASVVCLMNN FYPRDISVKW KIDGTERRDG VLDSVTDQDS
     KDSTYSMSST LSLTKADYES HNLYTCEVVH KTSSSPVVKS FNRNEC