ID   5052R_ASFB7             Reviewed;         489 AA.
AC   Q89702;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 65.
DE   RecName: Full=Protein MGF 505-2R;
GN   OrderedLocusNames=BA71V-025; ORFNames=A489R;
OS   African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10498;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA   Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA   Rodriguez J.F., Vinuela E.;
RT   "Analysis of the complete nucleotide sequence of African swine fever
RT   virus.";
RL   Virology 208:249-278(1995).
RN   [2]
RP   FUNCTION.
RX   PubMed=11238833; DOI=10.1128/jvi.75.7.3066-3076.2001;
RA   Zsak L., Lu Z., Burrage T.G., Neilan J.G., Kutish G.F., Moore D.M.,
RA   Rock D.L.;
RT   "African swine fever virus multigene family 360 and 530 genes are novel
RT   macrophage host range determinants.";
RL   J. Virol. 75:3066-3076(2001).
RN   [3]
RP   INDUCTION.
RX   PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA   Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA   Dixon L., Werner F.;
RT   "The African Swine Fever Virus Transcriptome.";
RL   J. Virol. 94:0-0(2020).
CC   -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC       efficient virus replication in macrophages.
CC       {ECO:0000269|PubMed:11238833}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       {ECO:0000269|PubMed:32075923}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 505 family. {ECO:0000305}.
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DR   EMBL; U02468; AAA17785.1; -; Genomic_DNA.
DR   EMBL; U18466; AAA65256.1; -; Genomic_DNA.
DR   RefSeq; NP_042720.1; NC_001659.2.
DR   SMR; Q89702; -.
DR   GeneID; 22220408; -.
DR   KEGG; vg:22220408; -.
DR   Proteomes; UP000000624; Genome.
DR   InterPro; IPR004858; MGF_505.
DR   Pfam; PF03158; DUF249; 1.
PE   2: Evidence at transcript level;
KW   Late protein; Reference proteome.
FT   CHAIN           1..489
FT                   /note="Protein MGF 505-2R"
FT                   /id="PRO_0000373317"
SQ   SEQUENCE   489 AA;  57695 MW;  E3B5723F7B6C326E CRC64;
     MFSLQDLCRK HLFILPDVFG EHVLQRLGLY WRCHGSLQRI GDDHILIRRD LILSTNEALR
     MAGEEGNNEV VKLLLLWKGN LHYAVIGALQ GDQYDLIHKY ENQIGDFHFI LPLIQDANTF
     EKCHALERFC GVSCLLKHAT KYNMLPILQK YQEELSMRAY LHETLFELAC LWQRYDVLKW
     IEQTMHVYDL KIMFNIAISK RDLTMYSLGY IFLFDRGNTE ATLLTQHLEK TAAKGLLHFV
     LETLKYGGNI DTVLTQAVKY NHRKLLDYFL RQLPRKHIEK LLLLAVQEKA SKKTLNLLLS
     HLNYSVKRIK KLLRYVIEYE STLVIKILLK KRVNLIDAML EKMVRYFSAT KVRTIMDELS
     ISPERVIKMA IQKMRTDIVI HTSYVWEDDL ERLTRLKNMV YTIKYEHGKK MLIKVMHGIY
     KNLLYGEREK VMFHLAKLYV AQNAATQFRD ICKDCYKLDV ARFKPRFKQL ILDCLEIVTK
     NLAIVSWKS