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5052R_ASFM2
ID   5052R_ASFM2             Reviewed;         524 AA.
AC   Q65128;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=Protein MGF 505-2R;
GN   OrderedLocusNames=Mal-035;
OS   African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10500;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=8030263; DOI=10.1006/viro.1994.1426;
RA   Yozawa T., Kutish G.F., Afonso C.L., Lu Z., Rock D.L.;
RT   "Two novel multigene families, 530 and 300, in the terminal variable
RT   regions of African swine fever virus genome.";
RL   Virology 202:997-1002(1994).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC       efficient virus replication in macrophages.
CC       {ECO:0000250|UniProtKB:Q89702}.
CC   -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 505 family. {ECO:0000305}.
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DR   EMBL; U03762; AAA50541.1; -; Genomic_DNA.
DR   EMBL; AY261361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   SMR; Q65128; -.
DR   Proteomes; UP000000860; Genome.
DR   InterPro; IPR004858; MGF_505.
DR   Pfam; PF03158; DUF249; 1.
PE   3: Inferred from homology;
KW   Late protein.
FT   CHAIN           1..524
FT                   /note="Protein MGF 505-2R"
FT                   /id="PRO_0000373319"
SQ   SEQUENCE   524 AA;  61872 MW;  D7F835311C0AFA48 CRC64;
     MFSLQDLCRK HLFILPDVFG EHVLQQLGLY WKRHGSLQRI GDDHILIRRD LILSTNEALK
     MAGEEGNNEV VKLLLLWEGN LHYAIIGALQ GDQYDLIHKY ENQIEDYHHI LPLIQDAKTF
     EKCHALERFC DVPCLLEHAT KHNMLPILQK YQEELSIRVY LRETLFELAC LWQRYDVLKW
     IEQTMHVYDL KIMFNIAISK RDLSMYSLGY VLLFDRGNIE ATFLTQHLEK TAAKGLLHFV
     LETLKYGGNL NIVLSQAVKY NHRKLLDYFL RQLPRKNIEK LLLLAVQEKA SKKTLNLLLS
     HLNYSVKHIK KLLRYVIEYE STLVIKLLLK KRVNLIDAVL EKNVRYFSAI KVRTIMDELS
     ISPERVIKMA IQKMRTDIVI QTSYIWEDDL ERLIRLKNMV YTIKYEHGKK MLIKVIHGIY
     KNLLYGEKEK VMFHLAKLYV AQNAATQFRD ICKDCCKLDV ARFKPRFKQL ILDCLEMVTK
     KSCFSIIEIL ENYIISLFVM KVITEEEKNL CLELLYKVIS YKTI
 
 
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