5052R_ASFM2
ID 5052R_ASFM2 Reviewed; 524 AA.
AC Q65128;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 03-AUG-2022, entry version 54.
DE RecName: Full=Protein MGF 505-2R;
GN OrderedLocusNames=Mal-035;
OS African swine fever virus (isolate Tick/Malawi/Lil 20-1/1983) (ASFV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Asfuvirales; Asfarviridae; Asfivirus.
OX NCBI_TaxID=10500;
OH NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=8030263; DOI=10.1006/viro.1994.1426;
RA Yozawa T., Kutish G.F., Afonso C.L., Lu Z., Rock D.L.;
RT "Two novel multigene families, 530 and 300, in the terminal variable
RT regions of African swine fever virus genome.";
RL Virology 202:997-1002(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Kutish G.F., Rock D.L.;
RT "African swine fever virus genomes.";
RL Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC efficient virus replication in macrophages.
CC {ECO:0000250|UniProtKB:Q89702}.
CC -!- INDUCTION: Expressed in the late phase of the viral replicative cycle.
CC {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the asfivirus MGF 505 family. {ECO:0000305}.
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DR EMBL; U03762; AAA50541.1; -; Genomic_DNA.
DR EMBL; AY261361; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR SMR; Q65128; -.
DR Proteomes; UP000000860; Genome.
DR InterPro; IPR004858; MGF_505.
DR Pfam; PF03158; DUF249; 1.
PE 3: Inferred from homology;
KW Late protein.
FT CHAIN 1..524
FT /note="Protein MGF 505-2R"
FT /id="PRO_0000373319"
SQ SEQUENCE 524 AA; 61872 MW; D7F835311C0AFA48 CRC64;
MFSLQDLCRK HLFILPDVFG EHVLQQLGLY WKRHGSLQRI GDDHILIRRD LILSTNEALK
MAGEEGNNEV VKLLLLWEGN LHYAIIGALQ GDQYDLIHKY ENQIEDYHHI LPLIQDAKTF
EKCHALERFC DVPCLLEHAT KHNMLPILQK YQEELSIRVY LRETLFELAC LWQRYDVLKW
IEQTMHVYDL KIMFNIAISK RDLSMYSLGY VLLFDRGNIE ATFLTQHLEK TAAKGLLHFV
LETLKYGGNL NIVLSQAVKY NHRKLLDYFL RQLPRKNIEK LLLLAVQEKA SKKTLNLLLS
HLNYSVKHIK KLLRYVIEYE STLVIKLLLK KRVNLIDAVL EKNVRYFSAI KVRTIMDELS
ISPERVIKMA IQKMRTDIVI QTSYIWEDDL ERLIRLKNMV YTIKYEHGKK MLIKVIHGIY
KNLLYGEKEK VMFHLAKLYV AQNAATQFRD ICKDCCKLDV ARFKPRFKQL ILDCLEMVTK
KSCFSIIEIL ENYIISLFVM KVITEEEKNL CLELLYKVIS YKTI