ID   5053R_ASFB7             Reviewed;         280 AA.
AC   Q89642;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 76.
DE   RecName: Full=Protein MGF 505-3R;
GN   OrderedLocusNames=BA71R-026; ORFNames=A280R;
OS   African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10498;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2325202; DOI=10.1128/jvi.64.5.2064-2072.1990;
RA   Almendral J.M., Almazan F., Blasco R., Vinuela E.;
RT   "Multigene families in African swine fever virus: family 110.";
RL   J. Virol. 64:2064-2072(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA   Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA   Rodriguez J.F., Vinuela E.;
RT   "Analysis of the complete nucleotide sequence of African swine fever
RT   virus.";
RL   Virology 208:249-278(1995).
RN   [3]
RP   FUNCTION.
RX   PubMed=11238833; DOI=10.1128/jvi.75.7.3066-3076.2001;
RA   Zsak L., Lu Z., Burrage T.G., Neilan J.G., Kutish G.F., Moore D.M.,
RA   Rock D.L.;
RT   "African swine fever virus multigene family 360 and 530 genes are novel
RT   macrophage host range determinants.";
RL   J. Virol. 75:3066-3076(2001).
RN   [4]
RP   INDUCTION.
RX   PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA   Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA   Dixon L., Werner F.;
RT   "The African Swine Fever Virus Transcriptome.";
RL   J. Virol. 94:0-0(2020).
CC   -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC       efficient virus replication in macrophages.
CC       {ECO:0000269|PubMed:11238833}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000269|PubMed:32075923}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 505 family. {ECO:0000305}.
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DR   EMBL; U02468; AAA17786.1; -; Genomic_DNA.
DR   EMBL; U18466; AAA65257.1; -; Genomic_DNA.
DR   RefSeq; NP_042721.1; NC_001659.2.
DR   SMR; Q89642; -.
DR   GeneID; 22220409; -.
DR   KEGG; vg:22220409; -.
DR   Proteomes; UP000000624; Genome.
DR   InterPro; IPR004858; MGF_505.
DR   Pfam; PF03158; DUF249; 1.
PE   2: Evidence at transcript level;
KW   Early protein; Reference proteome.
FT   CHAIN           1..280
FT                   /note="Protein MGF 505-3R"
FT                   /id="PRO_0000373322"
SQ   SEQUENCE   280 AA;  32509 MW;  3A986327D6878F3D CRC64;
     MSSSLQELCR KKLPDCILPE FFDDYVLQLL GLHWQDHGSL QRIEKNQILV QQEPIHINEA
     LKVAASEGNY EIVELLLSWE ADPRYAVVGA LESKYYDLVY KYYDLVKDCH DILPLIQNPE
     TFEKCHELNN PCSLKCLFKH AVIHDMLPIL QKYTYFLDGW EYCNQMLFEL ACSKKKYEMV
     VWIEGVLGIG KVTSLFTIAI SNRDLHLYSL GHLIILERMQ SCGQDPTFLL NHFLRDVSIK
     GLLPFVLKTI EYGGSKEIAI TLAKKYQHKH ILKYFETGKC