KAIB_SYNR3
ID KAIB_SYNR3 Reviewed; 110 AA.
AC A5GV19;
DT 05-FEB-2008, integrated into UniProtKB/Swiss-Prot.
DT 12-JUN-2007, sequence version 1.
DT 25-MAY-2022, entry version 71.
DE RecName: Full=Circadian clock protein KaiB {ECO:0000255|HAMAP-Rule:MF_01835};
GN Name=kaiB {ECO:0000255|HAMAP-Rule:MF_01835};
GN OrderedLocusNames=SynRCC307_1825;
OS Synechococcus sp. (strain RCC307).
OC Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC unclassified Synechococcus.
OX NCBI_TaxID=316278;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=RCC307;
RG Genoscope;
RL Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the KaiABC clock protein complex, which
CC constitutes the main circadian regulator in cyanobacteria. The KaiABC
CC complex may act as a promoter-non-specific transcription regulator that
CC represses transcription, possibly by acting on the state of chromosome
CC compaction. In the complex, it decreases the phosphorylation status of
CC KaiC. It has no effect on KaiC by itself, but instead needs the
CC presence of both KaiA and KaiC, suggesting that it acts by antagonizing
CC the interaction between KaiA and KaiC. {ECO:0000255|HAMAP-
CC Rule:MF_01835}.
CC -!- SUBUNIT: Homodimer. Component of the KaiABC complex, at least composed
CC of a KaiC homohexamer, a KaiB dimer and two KaiA dimers. The KaiABC
CC complex also interacts with SasA. {ECO:0000255|HAMAP-Rule:MF_01835}.
CC -!- SIMILARITY: Belongs to the KaiB family. {ECO:0000255|HAMAP-
CC Rule:MF_01835}.
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DR EMBL; CT978603; CAK28728.1; -; Genomic_DNA.
DR RefSeq; WP_011936241.1; NC_009482.1.
DR AlphaFoldDB; A5GV19; -.
DR SMR; A5GV19; -.
DR STRING; 316278.SynRCC307_1825; -.
DR EnsemblBacteria; CAK28728; CAK28728; SynRCC307_1825.
DR KEGG; syr:SynRCC307_1825; -.
DR eggNOG; COG4251; Bacteria.
DR HOGENOM; CLU_144073_0_0_3; -.
DR OMA; NEFKGVY; -.
DR OrthoDB; 1999883at2; -.
DR Proteomes; UP000001115; Chromosome.
DR GO; GO:0007623; P:circadian rhythm; IEA:UniProtKB-UniRule.
DR GO; GO:0042326; P:negative regulation of phosphorylation; IEA:InterPro.
DR CDD; cd02978; KaiB_like; 1.
DR HAMAP; MF_01835; KaiB; 1.
DR InterPro; IPR013474; Circ_KaiB.
DR InterPro; IPR039022; KaiB-like.
DR InterPro; IPR011649; KaiB_domain.
DR InterPro; IPR036249; Thioredoxin-like_sf.
DR PANTHER; PTHR41709; PTHR41709; 1.
DR Pfam; PF07689; KaiB; 1.
DR SMART; SM01248; KaiB; 1.
DR SUPFAM; SSF52833; SSF52833; 1.
DR TIGRFAMs; TIGR02654; circ_KaiB; 1.
PE 3: Inferred from homology;
KW Biological rhythms; Reference proteome.
FT CHAIN 1..110
FT /note="Circadian clock protein KaiB"
FT /id="PRO_1000070463"
SQ SEQUENCE 110 AA; 12411 MW; AEFEC6C6B8B1F178 CRC64;
MSPRKTYILK LYVAGNTPNS MRALKTLRNI LETEFLGVYA LKVIDVLKQP QLAEEDKILA
TPTLAKILPP PVRRIIGDLS DRERVLIGLD LLYEELSDDS NAQVLDDFSE