KAN3_ARATH
ID KAN3_ARATH Reviewed; 322 AA.
AC Q941I2;
DT 03-MAY-2011, integrated into UniProtKB/Swiss-Prot.
DT 01-DEC-2001, sequence version 1.
DT 03-AUG-2022, entry version 132.
DE RecName: Full=Probable transcription factor KAN3;
DE AltName: Full=Protein KANADI 3;
GN Name=KAN3; OrderedLocusNames=At4g17695; ORFNames=FCAALL;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11525739; DOI=10.1016/s0960-9822(01)00392-x;
RA Eshed Y., Baum S.F., Perea J.V., Bowman J.L.;
RT "Establishment of polarity in lateral organs of plants.";
RL Curr. Biol. 11:1251-1260(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9461215; DOI=10.1038/35140;
RA Bevan M., Bancroft I., Bent E., Love K., Goodman H.M., Dean C.,
RA Bergkamp R., Dirkse W., van Staveren M., Stiekema W., Drost L., Ridley P.,
RA Hudson S.-A., Patel K., Murphy G., Piffanelli P., Wedler H., Wedler E.,
RA Wambutt R., Weitzenegger T., Pohl T., Terryn N., Gielen J., Villarroel R.,
RA De Clercq R., van Montagu M., Lecharny A., Aubourg S., Gy I., Kreis M.,
RA Lao N., Kavanagh T., Hempel S., Kotter P., Entian K.-D., Rieger M.,
RA Schaefer M., Funk B., Mueller-Auer S., Silvey M., James R., Monfort A.,
RA Pons A., Puigdomenech P., Douka A., Voukelatou E., Milioni D.,
RA Hatzopoulos P., Piravandi E., Obermaier B., Hilbert H., Duesterhoeft A.,
RA Moores T., Jones J.D.G., Eneva T., Palme K., Benes V., Rechmann S.,
RA Ansorge W., Cooke R., Berger C., Delseny M., Voet M., Volckaert G.,
RA Mewes H.-W., Klosterman S., Schueller C., Chalwatzis N.;
RT "Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis
RT thaliana.";
RL Nature 391:485-488(1998).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP TISSUE SPECIFICITY.
RX PubMed=14561401; DOI=10.1016/j.cub.2003.09.035;
RA Emery J.F., Floyd S.K., Alvarez J., Eshed Y., Hawker N.P., Izhaki A.,
RA Baum S.F., Bowman J.L.;
RT "Radial patterning of Arabidopsis shoots by class III HD-ZIP and KANADI
RT genes.";
RL Curr. Biol. 13:1768-1774(2003).
RN [6]
RP FUNCTION.
RX PubMed=15286295; DOI=10.1104/pp.104.040196;
RA Hawker N.P., Bowman J.L.;
RT "Roles for Class III HD-Zip and KANADI genes in Arabidopsis root
RT development.";
RL Plant Physiol. 135:2261-2270(2004).
RN [7]
RP FUNCTION.
RX PubMed=17307928; DOI=10.1105/tpc.106.047472;
RA Izhaki A., Bowman J.L.;
RT "KANADI and class III HD-Zip gene families regulate embryo patterning and
RT modulate auxin flow during embryogenesis in Arabidopsis.";
RL Plant Cell 19:495-508(2007).
CC -!- FUNCTION: Probable transcription factor that regulates lateral organ
CC polarity. Plays a role in lateral root formation and development.
CC {ECO:0000269|PubMed:15286295, ECO:0000269|PubMed:17307928}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Expressed in developing phloem.
CC {ECO:0000269|PubMed:14561401}.
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DR EMBL; AY048690; AAL05438.1; -; mRNA.
DR EMBL; Z97344; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AL161547; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002687; AEE83935.1; -; Genomic_DNA.
DR RefSeq; NP_567535.1; NM_117878.3.
DR AlphaFoldDB; Q941I2; -.
DR SMR; Q941I2; -.
DR BioGRID; 12783; 12.
DR IntAct; Q941I2; 10.
DR STRING; 3702.AT4G17695.1; -.
DR PaxDb; Q941I2; -.
DR PRIDE; Q941I2; -.
DR ProteomicsDB; 250630; -.
DR EnsemblPlants; AT4G17695.1; AT4G17695.1; AT4G17695.
DR GeneID; 827490; -.
DR Gramene; AT4G17695.1; AT4G17695.1; AT4G17695.
DR KEGG; ath:AT4G17695; -.
DR Araport; AT4G17695; -.
DR TAIR; locus:505006489; AT4G17695.
DR eggNOG; ENOG502QRMZ; Eukaryota.
DR HOGENOM; CLU_047766_5_0_1; -.
DR OMA; QRCPSYE; -.
DR OrthoDB; 1076377at2759; -.
DR PhylomeDB; Q941I2; -.
DR PRO; PR:Q941I2; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q941I2; baseline and differential.
DR Genevisible; Q941I2; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IBA:GO_Central.
DR GO; GO:0010158; P:abaxial cell fate specification; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR009057; Homeobox-like_sf.
DR InterPro; IPR044847; KAN_fam.
DR InterPro; IPR006447; Myb_dom_plants.
DR PANTHER; PTHR31496; PTHR31496; 1.
DR SUPFAM; SSF46689; SSF46689; 1.
DR TIGRFAMs; TIGR01557; myb_SHAQKYF; 1.
PE 2: Evidence at transcript level;
KW Developmental protein; Differentiation; DNA-binding; Nucleus;
KW Reference proteome; Transcription; Transcription regulation.
FT CHAIN 1..322
FT /note="Probable transcription factor KAN3"
FT /id="PRO_0000408382"
FT DOMAIN 161..221
FT /note="HTH myb-type"
FT DNA_BIND 192..217
FT /note="H-T-H motif"
FT /evidence="ECO:0000250"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..244
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 267..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..35
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..322
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 322 AA; 36923 MW; 3CEF92B5256F24A7 CRC64;
MELFPSQPDL YLKISRRREE EQEKESQELQ EQEVERRLGF QSKASDLDNK SSNNLIHTLQ
FTSNNEATKI NSNQEHKESL DQDLRSIFMM RPIRGIPLYQ NQVLDHYYYS STSPNPFFFS
EVNGQHASRR LITNPNCSFN LHNRHRRQAQ PQPPRFTAKR GVRAPRMRWT TTLHAHFVHA
VQLLGGHERA TPKSVLELMD VQDLTLAHVK SHLQMYRTIK STEKPTTSSG QSDCENGSQV
NSEREARNLT GLWNNSSSEA RFQLKAKASS GVDISSNENE WKNRRCPSNE RLSSDSSSLT
GTRPETETPN LDFTLATPNL SP
