KAS2_KASSE
ID KAS2_KASSE Reviewed; 20 AA.
AC P0C011;
DT 07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2005, sequence version 1.
DT 25-MAY-2022, entry version 25.
DE RecName: Full=Kassinatuerin-2;
OS Kassina senegalensis (Senegal running frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Neobatrachia; Microhyloidea; Hyperoliidae; Kassina.
OX NCBI_TaxID=8415;
RN [1]
RP PROTEIN SEQUENCE, SYNTHESIS, AMIDATION AT ILE-20, AND MASS SPECTROMETRY.
RC TISSUE=Skin;
RX PubMed=10679222; DOI=10.1006/bbrc.2000.2136;
RA Mattute B., Knoop F.C., Conlon J.M.;
RT "Kassinatuerin-1: a peptide with broad-spectrum antimicrobial activity
RT isolated from the skin of the hyperoliid frog, Kassina senegalensis.";
RL Biochem. Biophys. Res. Commun. 268:433-436(2000).
CC -!- FUNCTION: Has no antimicrobial activities against bacteria (E.coli and
CC S.aureus) nor against the fungus C.albicans.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- TISSUE SPECIFICITY: Expressed by the skin dorsal glands.
CC -!- MASS SPECTROMETRY: Mass=2221.3; Method=Electrospray;
CC Evidence={ECO:0000269|PubMed:10679222};
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DR AlphaFoldDB; P0C011; -.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Secreted.
FT PEPTIDE 1..20
FT /note="Kassinatuerin-2"
FT /id="PRO_0000043809"
FT MOD_RES 20
FT /note="Isoleucine amide"
FT /evidence="ECO:0000269|PubMed:10679222"
SQ SEQUENCE 20 AA; 2223 MW; F0483E2134449379 CRC64;
FIQYLAPLIP HAVKAISDLI