ID   5054R_ASFB7             Reviewed;         505 AA.
AC   Q89768;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 68.
DE   RecName: Full=Protein MGF 505-4R;
GN   OrderedLocusNames=BA71R-027; ORFNames=A505R;
OS   African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10498;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA   Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA   Rodriguez J.F., Vinuela E.;
RT   "Analysis of the complete nucleotide sequence of African swine fever
RT   virus.";
RL   Virology 208:249-278(1995).
RN   [2]
RP   FUNCTION.
RX   PubMed=11238833; DOI=10.1128/jvi.75.7.3066-3076.2001;
RA   Zsak L., Lu Z., Burrage T.G., Neilan J.G., Kutish G.F., Moore D.M.,
RA   Rock D.L.;
RT   "African swine fever virus multigene family 360 and 530 genes are novel
RT   macrophage host range determinants.";
RL   J. Virol. 75:3066-3076(2001).
RN   [3]
RP   INDUCTION.
RX   PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA   Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA   Dixon L., Werner F.;
RT   "The African Swine Fever Virus Transcriptome.";
RL   J. Virol. 94:0-0(2020).
CC   -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC       efficient virus replication in macrophages.
CC       {ECO:0000269|PubMed:11238833}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000269|PubMed:32075923}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 505 family. {ECO:0000305}.
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DR   EMBL; U02468; AAA17787.1; -; Genomic_DNA.
DR   EMBL; U18466; AAA65258.1; -; Genomic_DNA.
DR   RefSeq; NP_042722.1; NC_001659.2.
DR   SMR; Q89768; -.
DR   GeneID; 22220410; -.
DR   KEGG; vg:22220410; -.
DR   Proteomes; UP000000624; Genome.
DR   InterPro; IPR004858; MGF_505.
DR   Pfam; PF03158; DUF249; 1.
PE   2: Evidence at transcript level;
KW   Early protein; Reference proteome.
FT   CHAIN           1..505
FT                   /note="Protein MGF 505-4R"
FT                   /id="PRO_0000373327"
SQ   SEQUENCE   505 AA;  59209 MW;  0BCD91F1776824C4 CRC64;
     MFSLQDICRK YLFQLPDSFD EYTLQVLGLY WEKHGSLQRI RKDAVFVQRN LIISINEALR
     IAASEGNGRV VKLLLSWEGN FHYVIIGALE GDHYDLIHKY GSQIEDYHMI LSSIHNANTF
     EKCHELSNCD MWCLIQNAIK YNMLPILQKH RNILTHEGEN QELFEMACEE QKYDIVLWIG
     QTLMLNEPEF IFDIAFERID FSLLTMGYSL LFNNKMSSID IHDEEDLISL LTEHLEKAAT
     KGCFFFMLET LKHGGNVNMA VLSKAVEYNH RKILDYFIRQ KCLSRKDIEK LLLVAISNSA
     SKKTLNLLLS YLNHSVKNII GKIVQSVLKN GDFTIIIFLK KKKINLVEPA LIGFINYYYS
     YCFLEQFIHE FDIRPEKMIK MAARKGKLNM IIEFLNEKYV HKDDLGAIFK FLKNLVCTMK
     HKKGKETLIV LIHKIYQVIQ LETKEKFKLL RFYVMHDATI QFISMYKDCF NLAGFKPFLL
     ECLDIAIKKN YPDMIRNIET LLKCE