ID   KATIP_XENLA             Reviewed;        1414 AA.
AC   Q5XK85;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 62.
DE   RecName: Full=Protein KATNIP homolog;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May control cilium integrity. {ECO:0000250|UniProtKB:O60303}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, cilium axoneme
CC       {ECO:0000250|UniProtKB:O60303}. Cytoplasm, cytoskeleton, cilium basal
CC       body {ECO:0000250|UniProtKB:O60303}. Cytoplasm, cytoskeleton
CC       {ECO:0000250|UniProtKB:O60303}. Note=When overexpressed, localizes to
CC       the cytoplasm where it associates with acetylated alpha-tubulin.
CC       {ECO:0000250|UniProtKB:O60303}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BC083029; AAH83029.1; -; mRNA.
DR   RefSeq; NP_001088144.1; NM_001094675.1.
DR   AlphaFoldDB; Q5XK85; -.
DR   BioGRID; 104930; 1.
DR   IntAct; Q5XK85; 1.
DR   GeneID; 494850; -.
DR   KEGG; xla:494850; -.
DR   CTD; 494850; -.
DR   Xenbase; XB-GENE-5819675; katnip.L.
DR   Proteomes; UP000186698; Chromosome 9_10L.
DR   Bgee; 494850; Expressed in egg cell and 16 other tissues.
DR   GO; GO:0042995; C:cell projection; IEA:UniProtKB-KW.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   InterPro; IPR026704; KATNIP.
DR   InterPro; IPR027859; KATNIP_dom.
DR   PANTHER; PTHR21534; PTHR21534; 1.
DR   Pfam; PF14652; DUF4457; 5.
PE   2: Evidence at transcript level;
KW   Cell projection; Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..1414
FT                   /note="Protein KATNIP homolog"
FT                   /id="PRO_0000313092"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          80..116
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          139..158
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          712..731
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          756..783
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          823..861
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          924..943
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        831..848
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        924..942
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1414 AA;  159672 MW;  D9E35F9BF6DC2162 CRC64;
     MHGKSLGSSR KNDSRSKIRQ EKESNIDFDE KHDEYLINLQ QRNRALNNSK AKDATQIKLQ
     HLEEGFSLYL NGANADLRKQ QSTQDLARES SKSSKIPDDG CSHLPGRRSQ TAPGKIQRKA
     WVQNSIQIKS ERGSRVYIGP NTKYSEDFES DDDMNEDQAS DQYKYFTDSE KNVPQGPGKK
     RLVLDASDVK ALRESLEISL CLQQDSKYSL DDDDADFVEE ELIECETPEL DSPSKTQLES
     KHQAFGHQRL LPGDFVVLEF NALDKKDGRM LTAKRKDNSE FYIPTKPVMV KNKTPRLKSS
     SFSSKDSFFP RPESRQEILL PTPRRSISEN KDSRPSVSTV VDAINNENEA ITRAISDGKT
     EKMTSGPSGI SEGVVTKAIE KINLMKISQQ KKLLKVLQDI DNDSSTNSNS EGEILKWDSV
     YLDPAVKDVI CITVEILSNW GNQYYIGLTE IQFFDLKNEE IYVSPHDVDI RNVDVPGDPT
     CLVNGKTLTT KEHFMWTCPF HPPVQLYFII RNATKSGDFD ISKMKIWNYN KALSDLDIGA
     KLVKIYKDET LVFDGLLAKG SGNQDFDYSN TIDLHSGQIK SSSFISDQFS DETQISNSLG
     ASNNIELKHQ SDGLVYTSEQ LSSILSEGSN QAKTSQQKDL HFENNTKGLR TFQDEALNKS
     FQHLALTSSS INCQEDITEG EVGIKMSYNK EEHFKINQSK DFNTMTAELQ MVSATSSKEP
     PPCPRDDNDL TVTDQLERTP GRKECSSLNR FPPWLSSSSN FQQKSHNQPT KNHLNASSST
     FTNKRSDQDI NQFLDEYVKS SNTYSNKNFK NCSQSKMLCS SSKMDNEDDL ENFSNQSSYN
     SDRPVSGRRK TVQMQDKSEK YEGASFHKTI NPVDTKNLRP RWQNDQENNL LESWTSLIKF
     NKSHRGRISN LEFEGDIFDE FLQQQQKAGK QSDSTKNGSS LMPKGATEIH LESEKEEGSN
     FEIPVLPYGQ HLCIKIVTTW GDRHYVGLNG IEVFASTGKP VEISRIRADP PDINILPAYG
     KDPRVVVNLI DGVNRTQDDM HLWLAPFSPG KLHFINLDFV EPCRVAMIRI WNYNKSRIHS
     FRGVKEVEIF LDNELIFKGE IAKASGTLSG AAEQFGDTIL FTTDDEILQA MSLFDETFSE
     ELKATETPTE HEIDSLRPST ADSIKEERPF TQAGLSEKLQ SNLTDVSENY SDKLPGIYSG
     KCLLLNFTMT WGDPHYLGLT GMEIVGRDGK ALAITLDALS ACPQDLSILP EYKDDLRTLD
     KLIDGVNITN EDTHMWLIPF ASGADHTITI NFNKSEDIAG IRFWNYNKSP EDTYRGAKIV
     YVTLDGHAIS PPGGFLIRKG PGNCHFDFAQ EILFVDYIHE QQILEKQLRS HSKCMELATM
     DYEAPLMPCG FIFQLQLITS WGDPYYIGLN GLEM