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KAX98_BUTOS
ID   KAX98_BUTOS             Reviewed;          56 AA.
AC   B8XH46;
DT   14-MAY-2014, integrated into UniProtKB/Swiss-Prot.
DT   03-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 24.
DE   RecName: Full=Potassium channel toxin alpha-KTx 9.8 {ECO:0000305};
DE   AltName: Full=Toxin Tx784 {ECO:0000312|EMBL:ACJ23155.1};
DE   Flags: Precursor;
OS   Buthus occitanus israelis (Common yellow scorpion) (Buthus israelis).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Scorpiones; Buthida; Buthoidea; Buthidae; Buthus.
OX   NCBI_TaxID=539894;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RA   Zilberberg N., Kozminsky-Atias A.;
RT   "Buthus occitanus israelis scorpion toxin.";
RL   Submitted (OCT-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Potassium channel inhibitor. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|Ref.1}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland. {ECO:0000305|Ref.1}.
CC   -!- DOMAIN: Has the structural arrangement of an alpha-helix connected to a
CC       beta-sheet by disulfide bonds (CSalpha/beta).
CC       {ECO:0000250|UniProtKB:Q9NJP7}.
CC   -!- SIMILARITY: Belongs to the short scorpion toxin superfamily. Potassium
CC       channel inhibitor family. Alpha-KTx 09 subfamily. {ECO:0000305}.
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DR   EMBL; FJ360835; ACJ23155.1; -; mRNA.
DR   AlphaFoldDB; B8XH46; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0008200; F:ion channel inhibitor activity; IEA:InterPro.
DR   GO; GO:0015459; F:potassium channel regulator activity; IEA:UniProtKB-KW.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   InterPro; IPR036574; Scorpion_toxin-like_sf.
DR   InterPro; IPR008911; Toxin_alpha-KTx_8/9.
DR   Pfam; PF05453; Toxin_6; 1.
DR   SUPFAM; SSF57095; SSF57095; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Ion channel impairing toxin; Neurotoxin;
KW   Potassium channel impairing toxin; Secreted; Signal; Toxin.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   PROPEP          20..28
FT                   /evidence="ECO:0000250"
FT                   /id="PRO_0000428961"
FT   PEPTIDE         29..56
FT                   /note="Potassium channel toxin alpha-KTx 9.8"
FT                   /evidence="ECO:0000305|Ref.1"
FT                   /id="PRO_0000428962"
FT   DISULFID        31..47
FT                   /evidence="ECO:0000250|UniProtKB:Q9NJP7"
FT   DISULFID        34..52
FT                   /evidence="ECO:0000250|UniProtKB:Q9NJP7"
FT   DISULFID        38..54
FT                   /evidence="ECO:0000250|UniProtKB:Q9NJP7"
SQ   SEQUENCE   56 AA;  6032 MW;  70953032042F85BD CRC64;
     MSRLFTLVLI VLAMNVMMAI ISDPVVEAVG CEECPMHCKG KMAKPTCDDG VCNCNV
 
 
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