KBAZ_ECOLU
ID KBAZ_ECOLU Reviewed; 426 AA.
AC B7NDB8;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 10-FEB-2009, sequence version 1.
DT 03-AUG-2022, entry version 65.
DE RecName: Full=D-tagatose-1,6-bisphosphate aldolase subunit KbaZ {ECO:0000255|HAMAP-Rule:MF_01295};
GN Name=kbaZ {ECO:0000255|HAMAP-Rule:MF_01295}; OrderedLocusNames=ECUMN_3614;
OS Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=585056;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UMN026 / ExPEC;
RX PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT "Organised genome dynamics in the Escherichia coli species results in
RT highly diverse adaptive paths.";
RL PLoS Genet. 5:E1000344-E1000344(2009).
CC -!- FUNCTION: Component of the tagatose-1,6-bisphosphate aldolase KbaYZ
CC that is required for full activity and stability of the Y subunit.
CC Could have a chaperone-like function for the proper and stable folding
CC of KbaY. When expressed alone, KbaZ does not show any aldolase
CC activity. {ECO:0000255|HAMAP-Rule:MF_01295}.
CC -!- PATHWAY: Carbohydrate metabolism; D-tagatose 6-phosphate degradation;
CC D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-
CC phosphate: step 2/2. {ECO:0000255|HAMAP-Rule:MF_01295}.
CC -!- SUBUNIT: Forms a complex with KbaY. {ECO:0000255|HAMAP-Rule:MF_01295}.
CC -!- SIMILARITY: Belongs to the GatZ/KbaZ family. KbaZ subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01295}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CU928163; CAR14768.1; -; Genomic_DNA.
DR RefSeq; WP_000681943.1; NC_011751.1.
DR RefSeq; YP_002414273.1; NC_011751.1.
DR AlphaFoldDB; B7NDB8; -.
DR SMR; B7NDB8; -.
DR STRING; 585056.ECUMN_3614; -.
DR EnsemblBacteria; CAR14768; CAR14768; ECUMN_3614.
DR KEGG; eum:ECUMN_3614; -.
DR PATRIC; fig|585056.7.peg.3794; -.
DR HOGENOM; CLU_053334_0_0_6; -.
DR OMA; QRHFSYS; -.
DR UniPathway; UPA00704; UER00716.
DR Proteomes; UP000007097; Chromosome.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:2001059; P:D-tagatose 6-phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.20.20.70; -; 1.
DR HAMAP; MF_01295; Tagatose_aldol_KbaZ; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR012062; GatZ/KbaZ-like.
DR InterPro; IPR023435; TagBP_ald_KbaZ.
DR Pfam; PF08013; GatZ_KbaZ-like; 1.
DR PIRSF; PIRSF009264; TagBP_ald_AgaZ; 1.
DR TIGRFAMs; TIGR02810; agaZ_gatZ; 1.
PE 3: Inferred from homology;
FT CHAIN 1..426
FT /note="D-tagatose-1,6-bisphosphate aldolase subunit KbaZ"
FT /id="PRO_0000372534"
SQ SEQUENCE 426 AA; 47206 MW; 55AC5DA9CCA62641 CRC64;
MKHLTEMVRQ HKAGKTNGIY AVCSAHPLVL EAAIRYASAN QTPLLIEATS NQVDQFGGYT
GMTPADFRGF VCQLADSLNF PQDALILGGD HLGPNRWQNL PAAQAMANAD DLIKSYVAAG
FKKIHLDCSM SCQDDPVPLT DDIVAERAAR LAKVAEETCR EHFGEADLVY VIGTEVPVPG
GAHETLSELA VTTPDAARAT LEAHRHAFEK QGLSAIWPRI IALVVQPGVE FDHTNVIDYQ
PVKATALSQM VENYETLIFE AHSTDYQTPQ SLRQLVIDHF AILKVGPALT FALREALFSL
AAIEEELVPA KACSGLRQVL ENVMLDRPEY WQSHYHGDGN ARRLARGYSY SDRVRYYWPD
SQIDDAFAHL VRNLADSPIP LPLISQYLPL QYVKVRSGEL QPTPRELIIN HIQDILAQYH
TACEGQ