ID   KBAZ_ECOSE              Reviewed;         426 AA.
AC   B6I1K5;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   16-DEC-2008, sequence version 1.
DT   03-AUG-2022, entry version 71.
DE   RecName: Full=D-tagatose-1,6-bisphosphate aldolase subunit KbaZ {ECO:0000255|HAMAP-Rule:MF_01295};
GN   Name=kbaZ {ECO:0000255|HAMAP-Rule:MF_01295}; OrderedLocusNames=ECSE_3416;
OS   Escherichia coli (strain SE11).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=409438;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SE11;
RX   PubMed=18931093; DOI=10.1093/dnares/dsn026;
RA   Oshima K., Toh H., Ogura Y., Sasamoto H., Morita H., Park S.-H., Ooka T.,
RA   Iyoda S., Taylor T.D., Hayashi T., Itoh K., Hattori M.;
RT   "Complete genome sequence and comparative analysis of the wild-type
RT   commensal Escherichia coli strain SE11 isolated from a healthy adult.";
RL   DNA Res. 15:375-386(2008).
CC   -!- FUNCTION: Component of the tagatose-1,6-bisphosphate aldolase KbaYZ
CC       that is required for full activity and stability of the Y subunit.
CC       Could have a chaperone-like function for the proper and stable folding
CC       of KbaY. When expressed alone, KbaZ does not show any aldolase
CC       activity. {ECO:0000255|HAMAP-Rule:MF_01295}.
CC   -!- PATHWAY: Carbohydrate metabolism; D-tagatose 6-phosphate degradation;
CC       D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-
CC       phosphate: step 2/2. {ECO:0000255|HAMAP-Rule:MF_01295}.
CC   -!- SUBUNIT: Forms a complex with KbaY. {ECO:0000255|HAMAP-Rule:MF_01295}.
CC   -!- SIMILARITY: Belongs to the GatZ/KbaZ family. KbaZ subfamily.
CC       {ECO:0000255|HAMAP-Rule:MF_01295}.
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DR   EMBL; AP009240; BAG78940.1; -; Genomic_DNA.
DR   RefSeq; WP_000681921.1; NC_011415.1.
DR   AlphaFoldDB; B6I1K5; -.
DR   SMR; B6I1K5; -.
DR   EnsemblBacteria; BAG78940; BAG78940; ECSE_3416.
DR   GeneID; 66672969; -.
DR   KEGG; ecy:ECSE_3416; -.
DR   HOGENOM; CLU_053334_0_0_6; -.
DR   OMA; QRHFSYS; -.
DR   UniPathway; UPA00704; UER00716.
DR   Proteomes; UP000008199; Chromosome.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:2001059; P:D-tagatose 6-phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR   Gene3D; 3.20.20.70; -; 1.
DR   HAMAP; MF_01295; Tagatose_aldol_KbaZ; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR012062; GatZ/KbaZ-like.
DR   InterPro; IPR023435; TagBP_ald_KbaZ.
DR   Pfam; PF08013; GatZ_KbaZ-like; 1.
DR   PIRSF; PIRSF009264; TagBP_ald_AgaZ; 1.
DR   TIGRFAMs; TIGR02810; agaZ_gatZ; 1.
PE   3: Inferred from homology;
FT   CHAIN           1..426
FT                   /note="D-tagatose-1,6-bisphosphate aldolase subunit KbaZ"
FT                   /id="PRO_0000372527"
SQ   SEQUENCE   426 AA;  47218 MW;  FC97956E662EB389 CRC64;
     MKHLTEMVRQ HKAGKTNGIY AVCSAHPLVL EAAIRYASAN QTPLLIEATS NQVDQFGGYT
     GMTPADFRGF VCQLADSLNF PQDALILGGD HLGPNRWQNL PAAQAMANAD DLIKSYVAAG
     FKKIHLDCSM SCQDDPIPLT DDIVAERAAR LAKVAEETCL EHFGEADLEY VIGTEVPVPG
     GAHETLSELA VTTPDAARAT LEAHRHAFEK QGLNAIWPRI IALVVQPGVE FDHTNVIDYQ
     PAKASALSQM VENYETLIFE AHSTDYQTPQ SLRQLVIDHF AILKVGPALT FALREALFSL
     AAIEEELVPA KACSGLRQVL EDVMLDRPEY WQSHYHGDGN ARRLARGYSY SDRVRYYWPD
     SQIDDAFAHL VRNLADSPIP LPLISQYLPL QYVKVRSGEL QPTPRELIIN HIQDILAQYY
     TACEGQ