KBAZ_ECOUT
ID KBAZ_ECOUT Reviewed; 426 AA.
AC Q1R6K7;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-MAY-2006, sequence version 1.
DT 03-AUG-2022, entry version 80.
DE RecName: Full=D-tagatose-1,6-bisphosphate aldolase subunit KbaZ {ECO:0000255|HAMAP-Rule:MF_01295};
GN Name=kbaZ {ECO:0000255|HAMAP-Rule:MF_01295}; Synonyms=agaZ;
GN OrderedLocusNames=UTI89_C3561;
OS Escherichia coli (strain UTI89 / UPEC).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=364106;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UTI89 / UPEC;
RX PubMed=16585510; DOI=10.1073/pnas.0600938103;
RA Chen S.L., Hung C.-S., Xu J., Reigstad C.S., Magrini V., Sabo A.,
RA Blasiar D., Bieri T., Meyer R.R., Ozersky P., Armstrong J.R., Fulton R.S.,
RA Latreille J.P., Spieth J., Hooton T.M., Mardis E.R., Hultgren S.J.,
RA Gordon J.I.;
RT "Identification of genes subject to positive selection in uropathogenic
RT strains of Escherichia coli: a comparative genomics approach.";
RL Proc. Natl. Acad. Sci. U.S.A. 103:5977-5982(2006).
CC -!- FUNCTION: Component of the tagatose-1,6-bisphosphate aldolase KbaYZ
CC that is required for full activity and stability of the Y subunit.
CC Could have a chaperone-like function for the proper and stable folding
CC of KbaY. When expressed alone, KbaZ does not show any aldolase
CC activity. {ECO:0000255|HAMAP-Rule:MF_01295}.
CC -!- PATHWAY: Carbohydrate metabolism; D-tagatose 6-phosphate degradation;
CC D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-
CC phosphate: step 2/2. {ECO:0000255|HAMAP-Rule:MF_01295}.
CC -!- SUBUNIT: Forms a complex with KbaY. {ECO:0000255|HAMAP-Rule:MF_01295}.
CC -!- SIMILARITY: Belongs to the GatZ/KbaZ family. KbaZ subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01295}.
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DR EMBL; CP000243; ABE09007.1; -; Genomic_DNA.
DR RefSeq; WP_000681931.1; NC_007946.1.
DR AlphaFoldDB; Q1R6K7; -.
DR SMR; Q1R6K7; -.
DR EnsemblBacteria; ABE09007; ABE09007; UTI89_C3561.
DR KEGG; eci:UTI89_C3561; -.
DR HOGENOM; CLU_053334_0_0_6; -.
DR OMA; QRHFSYS; -.
DR UniPathway; UPA00704; UER00716.
DR Proteomes; UP000001952; Chromosome.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:2001059; P:D-tagatose 6-phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.20.20.70; -; 1.
DR HAMAP; MF_01295; Tagatose_aldol_KbaZ; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR012062; GatZ/KbaZ-like.
DR InterPro; IPR023435; TagBP_ald_KbaZ.
DR Pfam; PF08013; GatZ_KbaZ-like; 1.
DR PIRSF; PIRSF009264; TagBP_ald_AgaZ; 1.
DR TIGRFAMs; TIGR02810; agaZ_gatZ; 1.
PE 3: Inferred from homology;
FT CHAIN 1..426
FT /note="D-tagatose-1,6-bisphosphate aldolase subunit KbaZ"
FT /id="PRO_0000372529"
SQ SEQUENCE 426 AA; 47218 MW; 92DD6B4128A967E7 CRC64;
MKHLTEMVRQ HKAGKTNGIY AVCSAHPLVL EAAIRYASAN QTPLLIEATS NQVDQFGGYT
GMTPADFRGF VCQLADSLNF PQDALILGGD HLGPNRWQNL PAAQAMANAD DLIKSYVAAG
FKKIHLDCSM SCQDDPIPLT DDIVAERAAR LAKVAEETCR EHFGEADLEY VIGTEVPVPG
GAHETLSELA VTTPDAARAT LEAHRHAFEK QGLNAIWPRI IALVVQPGVE FDHTNVIDYQ
PAKAAALSQM VENYETLIFE AHSTDYQTPQ SLRQLVIDHF AILKVGPALT FALREALFSL
AAIEEELVPA KACSGLRQVL ENVMLDRPEY WQSHYHGDGN ARRLARGYSY SDRVRYYWPD
SQIDDAFAHL VRNLADSPIP LPLISQYLPL QYVKVRSGEL QPTPRELIIN HIQDILAQYH
TACEGQ