KBAZ_SHIFL
ID KBAZ_SHIFL Reviewed; 426 AA.
AC Q83JH9; Q7BZS8;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=D-tagatose-1,6-bisphosphate aldolase subunit KbaZ {ECO:0000255|HAMAP-Rule:MF_01295};
GN Name=kbaZ {ECO:0000255|HAMAP-Rule:MF_01295}; Synonyms=agaZ;
GN OrderedLocusNames=SF3167, S3382;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- FUNCTION: Component of the tagatose-1,6-bisphosphate aldolase KbaYZ
CC that is required for full activity and stability of the Y subunit.
CC Could have a chaperone-like function for the proper and stable folding
CC of KbaY. When expressed alone, KbaZ does not show any aldolase
CC activity. {ECO:0000255|HAMAP-Rule:MF_01295}.
CC -!- PATHWAY: Carbohydrate metabolism; D-tagatose 6-phosphate degradation;
CC D-glyceraldehyde 3-phosphate and glycerone phosphate from D-tagatose 6-
CC phosphate: step 2/2. {ECO:0000255|HAMAP-Rule:MF_01295}.
CC -!- SUBUNIT: Forms a complex with KbaY. {ECO:0000255|HAMAP-Rule:MF_01295}.
CC -!- SIMILARITY: Belongs to the GatZ/KbaZ family. KbaZ subfamily.
CC {ECO:0000255|HAMAP-Rule:MF_01295}.
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DR EMBL; AE005674; AAN44636.1; -; Genomic_DNA.
DR EMBL; AE014073; AAP18451.1; -; Genomic_DNA.
DR RefSeq; NP_708929.1; NC_004337.2.
DR RefSeq; WP_000681907.1; NZ_UIQL01000039.1.
DR AlphaFoldDB; Q83JH9; -.
DR SMR; Q83JH9; -.
DR STRING; 198214.SF3167; -.
DR EnsemblBacteria; AAN44636; AAN44636; SF3167.
DR EnsemblBacteria; AAP18451; AAP18451; S3382.
DR GeneID; 1027164; -.
DR KEGG; sfl:SF3167; -.
DR KEGG; sfx:S3382; -.
DR PATRIC; fig|198214.7.peg.3763; -.
DR HOGENOM; CLU_053334_0_0_6; -.
DR OMA; QRHFSYS; -.
DR OrthoDB; 395879at2; -.
DR UniPathway; UPA00704; UER00716.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:2001059; P:D-tagatose 6-phosphate catabolic process; IEA:UniProtKB-UniPathway.
DR Gene3D; 3.20.20.70; -; 1.
DR HAMAP; MF_01295; Tagatose_aldol_KbaZ; 1.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR012062; GatZ/KbaZ-like.
DR InterPro; IPR023435; TagBP_ald_KbaZ.
DR Pfam; PF08013; GatZ_KbaZ-like; 1.
DR PIRSF; PIRSF009264; TagBP_ald_AgaZ; 1.
DR TIGRFAMs; TIGR02810; agaZ_gatZ; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..426
FT /note="D-tagatose-1,6-bisphosphate aldolase subunit KbaZ"
FT /id="PRO_0000372545"
SQ SEQUENCE 426 AA; 47248 MW; AF4B466C22837D89 CRC64;
MKHLTEMVRQ HKAGKTNAIY AVCSAHPLVL EAAIRYASAN QTPLLIEATS NQVDQFGGYT
GMTPADFRGF VCQLADSLNF PQDALILGGD HLGPNRWQNL PAAQAMANAD DLIKSYVAAG
FKKIHLDCSM SCQDDPIPLT DDIVAERAAR LAKVAEETCR EHFGEADLEY VIGTEVPVPG
GAHETLSELA VTTPDAARAT LEAHRHAFEK QGLNAIWPRI IALVVQPGVE FDHTNVIDYQ
PAKASALSQM VENYETLIFE AHSTDYQTPQ SLRQLVIDHF AILKVGPALT FALREALFSL
AAIEEELVPA KACSGLRQVL ENVMLDRPEY WQSHYHGDGN ARRLARGYSY SDRVRYYWPD
SQIDDAFAHL VRNLADSPIP LPLISQYLPL QYVKVRSGEL QPTPRELIIN HIQDILAQYH
TACEGQ