KBP3_CAEEL
ID KBP3_CAEEL Reviewed; 134 AA.
AC O45406;
DT 02-MAY-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 3.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Kinetochore-binding protein 3;
GN Name=kbp-3; ORFNames=F26H11.1;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Bristol N2;
RA Kohara Y., Shin-i T., Suzuki Y., Sugano S., Potdevin M., Thierry-Mieg Y.,
RA Thierry-Mieg D., Thierry-Mieg J.;
RT "The Caenorhabditis elegans transcriptome project, a complementary view of
RT the genome.";
RL Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP IDENTIFICATION AS A KINETOCHORE PROTEIN.
RX PubMed=15371340; DOI=10.1101/gad.1234104;
RA Cheeseman I.M., Niessen S., Anderson S., Hyndman F., Yates J.R. III,
RA Oegema K., Desai A.;
RT "A conserved protein network controls assembly of the outer kinetochore and
RT its ability to sustain tension.";
RL Genes Dev. 18:2255-2268(2004).
CC -!- SUBCELLULAR LOCATION: Nucleus. Chromosome, centromere, kinetochore.
CC Chromosome. Note=Associated with kinetochores. Localize to kinetochores
CC throughout mitosis. Begin to localize to chromosomes during prophase
CC and persist on chromosomes until the end of mitosis.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; Z81515; CAB04194.3; -; Genomic_DNA.
DR EMBL; AF303250; AAG50208.1; -; mRNA.
DR PIR; A88363; A88363.
DR PIR; T21434; T21434.
DR RefSeq; NP_496993.1; NM_064592.3.
DR AlphaFoldDB; O45406; -.
DR SMR; O45406; -.
DR BioGRID; 40378; 3.
DR ComplexPortal; CPX-806; Ndc80 complex.
DR IntAct; O45406; 6.
DR STRING; 6239.F26H11.1; -.
DR EPD; O45406; -.
DR PaxDb; O45406; -.
DR PeptideAtlas; O45406; -.
DR EnsemblMetazoa; F26H11.1.1; F26H11.1.1; WBGene00009179.
DR GeneID; 175097; -.
DR KEGG; cel:CELE_F26H11.1; -.
DR UCSC; F26H11.1; c. elegans.
DR CTD; 175097; -.
DR WormBase; F26H11.1; CE26712; WBGene00009179; kbp-3.
DR eggNOG; ENOG502TJ50; Eukaryota.
DR HOGENOM; CLU_156774_0_0_1; -.
DR InParanoid; O45406; -.
DR OMA; KLENCAQ; -.
DR PRO; PR:O45406; -.
DR Proteomes; UP000001940; Chromosome II.
DR Bgee; WBGene00009179; Expressed in germ line (C elegans) and 4 other tissues.
DR GO; GO:0000776; C:kinetochore; IDA:UniProtKB.
DR GO; GO:0005874; C:microtubule; IDA:ComplexPortal.
DR GO; GO:0031262; C:Ndc80 complex; IDA:WormBase.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0008608; P:attachment of spindle microtubules to kinetochore; IDA:ComplexPortal.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
PE 2: Evidence at transcript level;
KW Cell cycle; Cell division; Centromere; Chromosome; Kinetochore; Mitosis;
KW Nucleus; Reference proteome.
FT CHAIN 1..134
FT /note="Kinetochore-binding protein 3"
FT /id="PRO_0000065317"
SQ SEQUENCE 134 AA; 15930 MW; E3A3A7D2DB5FACBE CRC64;
MESLNEYMDK IINRLKAVNE KDELVDEGMR KLQKCQEKIM KTRIDAQKHI DERHEQQSFE
QQLLNKNMFE TEQLEEKLKR LDDENKIGNE REFNKKLEAI SAKWTDDVNL LKTTPNEPND
GNRKKLSNLS NILV