ID   KBP_BOVIN               Reviewed;         621 AA.
AC   Q3SYS9;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2005, sequence version 1.
DT   03-AUG-2022, entry version 93.
DE   RecName: Full=KIF-binding protein;
DE   AltName: Full=KIF1-binding protein;
GN   Name=KIFBP; Synonyms=KBP;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Ileum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for organization of axonal microtubules, and axonal
CC       outgrowth and maintenance during peripheral and central nervous system
CC       development. {ECO:0000250|UniProtKB:Q96EK5}.
CC   -!- SUBUNIT: Interacts with KIF1B. Interacts with STMN2.
CC       {ECO:0000250|UniProtKB:Q96EK5}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000250|UniProtKB:Q96EK5}.
CC   -!- SIMILARITY: Belongs to the KIF-binding protein family. {ECO:0000305}.
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DR   EMBL; BC103410; AAI03411.1; -; mRNA.
DR   RefSeq; NP_001029731.1; NM_001034559.2.
DR   AlphaFoldDB; Q3SYS9; -.
DR   SMR; Q3SYS9; -.
DR   STRING; 9913.ENSBTAP00000019353; -.
DR   PaxDb; Q3SYS9; -.
DR   PRIDE; Q3SYS9; -.
DR   Ensembl; ENSBTAT00000019353; ENSBTAP00000019353; ENSBTAG00000014561.
DR   GeneID; 527433; -.
DR   KEGG; bta:527433; -.
DR   CTD; 26128; -.
DR   VEuPathDB; HostDB:ENSBTAG00000014561; -.
DR   VGNC; VGNC:30592; KIFBP.
DR   eggNOG; ENOG502QPZT; Eukaryota.
DR   GeneTree; ENSGT00390000013819; -.
DR   HOGENOM; CLU_019859_1_0_1; -.
DR   InParanoid; Q3SYS9; -.
DR   OMA; ICRECWY; -.
DR   OrthoDB; 1516717at2759; -.
DR   TreeFam; TF324211; -.
DR   Proteomes; UP000009136; Chromosome 28.
DR   Bgee; ENSBTAG00000014561; Expressed in occipital lobe and 103 other tissues.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR   GO; GO:0019894; F:kinesin binding; IEA:Ensembl.
DR   GO; GO:0021952; P:central nervous system projection neuron axonogenesis; IBA:GO_Central.
DR   GO; GO:0001701; P:in utero embryonic development; IEA:Ensembl.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IBA:GO_Central.
DR   GO; GO:0006839; P:mitochondrial transport; ISS:UniProtKB.
DR   GO; GO:1990535; P:neuron projection maintenance; IBA:GO_Central.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR022083; KBP.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR46321; PTHR46321; 1.
DR   Pfam; PF12309; KBP_C; 1.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Cytoskeleton; Developmental protein; Differentiation;
KW   Neurogenesis; Phosphoprotein; Reference proteome.
FT   CHAIN           1..621
FT                   /note="KIF-binding protein"
FT                   /id="PRO_0000334516"
FT   MOD_RES         178
FT                   /note="Phosphoserine"
FT                   /evidence="ECO:0000250|UniProtKB:Q96EK5"
SQ   SEQUENCE   621 AA;  72040 MW;  11862B2D785F464A CRC64;
     MADSPWDEIR EKFQTALALS RVELHKNPEK EPYKSKYSAR ALLEEVKALL GPAPEDEDER
     PQADDSLGAG EHALGLPAEL VEAEGPVAQG AVRRAVIEFH LGVNHIDTEE LSAGEEHLVK
     CLRLLRKYRL SHDCVSLYIQ AQNNLGILWS EREEIETAQA YLESSEALYN QYMKEIGSPP
     LDPTEHFLPE EEKLPEQERS KRFEKVYTHN LYYLAQVYQH MEMFEKAAHY CHSTLKRQLE
     HNAYHPMEWA INAATLSQFY INKQCFMEAR HCLSAANVIF GQIGKIRTTE DTTEAEGDVP
     ELYHQRKGEI ARCWIKYCLT LMQNAQLSMQ DNIGELDLDK QSELRALRKK ELDEEESVRK
     KAVQFGTGEL CDAISAVEEK VSYLRPLDFE EARELFLTGQ HYVFEAKEFF QIDGYVTDHI
     EVVQDHSALF KVLAFFETDM ERRCKMHKRR IAMLEPLIVD LNPQYYLLVN RQIQFEIAHA
     YYDMMDLKVA IADKLRDPDS HIVKKINNLN KSALKYYQLF LDSLRDPNKV FPEHIGEDVL
     RPAMLAKFRV ARLYGKIITA DPKKELENLA TSLEHYKFIV DYCEKHPEAA QEIEVELELS
     KEMVSLLPTK MERFRTKMAL T