ID   KBP_XENTR               Reviewed;         616 AA.
AC   Q0IIZ5;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=KIF-binding protein;
DE   AltName: Full=KIF1-binding protein {ECO:0000250|UniProtKB:Q96EK5};
GN   Name=Kifbp {ECO:0000250|UniProtKB:Q96EK5};
GN   Synonyms=kbp {ECO:0000250|UniProtKB:Q96EK5}, Kif1bp;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Testis;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for organization of axonal microtubules, and axonal
CC       outgrowth and maintenance during peripheral and central nervous system
CC       development. {ECO:0000250|UniProtKB:Q96EK5}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC       {ECO:0000250|UniProtKB:Q96EK5}.
CC   -!- SIMILARITY: Belongs to the KIF-binding protein family. {ECO:0000305}.
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DR   EMBL; BC121345; AAI21346.1; -; mRNA.
DR   RefSeq; NP_001072796.1; NM_001079328.1.
DR   AlphaFoldDB; Q0IIZ5; -.
DR   SMR; Q0IIZ5; -.
DR   STRING; 8364.ENSXETP00000019414; -.
DR   PaxDb; Q0IIZ5; -.
DR   DNASU; 780257; -.
DR   Ensembl; ENSXETT00000019414; ENSXETP00000019414; ENSXETG00000008834.
DR   GeneID; 780257; -.
DR   KEGG; xtr:780257; -.
DR   CTD; 26128; -.
DR   Xenbase; XB-GENE-5934501; kifbp.
DR   eggNOG; ENOG502QPZT; Eukaryota.
DR   InParanoid; Q0IIZ5; -.
DR   OMA; ICRECWY; -.
DR   OrthoDB; 1516717at2759; -.
DR   PhylomeDB; Q0IIZ5; -.
DR   TreeFam; TF324211; -.
DR   Proteomes; UP000008143; Chromosome 7.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000008834; Expressed in brain and 12 other tissues.
DR   GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR   GO; GO:0021952; P:central nervous system projection neuron axonogenesis; IBA:GO_Central.
DR   GO; GO:0000226; P:microtubule cytoskeleton organization; IBA:GO_Central.
DR   GO; GO:0006839; P:mitochondrial transport; ISS:UniProtKB.
DR   GO; GO:1990535; P:neuron projection maintenance; IBA:GO_Central.
DR   Gene3D; 1.25.40.10; -; 1.
DR   InterPro; IPR022083; KBP.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   PANTHER; PTHR46321; PTHR46321; 1.
DR   Pfam; PF12309; KBP_C; 1.
DR   SUPFAM; SSF48452; SSF48452; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Cytoskeleton; Developmental protein; Differentiation;
KW   Neurogenesis; Reference proteome.
FT   CHAIN           1..616
FT                   /note="KIF-binding protein"
FT                   /id="PRO_0000334519"
FT   REGION          52..78
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   616 AA;  72376 MW;  09A39346E6D6F429 CRC64;
     MADDWRQVCE TYRRAITLSD VESKNDPENE PYRSKYRARE LLREVRVLLC PEEEEESEAE
     GKEERRDGPE SGGRRGESGE LLAARLAVVE FRLGLNHTET EEMSAGEEHL VKSGRIMERF
     RLSEEGVSVY IQAQNNLGIL WADRGEIRVA QRYLESAESL YYQYMKEIGK PAIDPDEHFF
     SEEQKLTEQE RTKRFERVYT HTLYYLAQVY KHLKQDEKAA QYCHTTLQRQ LEYDSYNPVE
     WAINAATLSQ YYVTKQCYME SRHCLAAANV IFSKAEQIPS AEAAKENEAE QERLDLLRQK
     KAEIARCWVK YCLNLLQDAR KKLEDNIGEL DVDIQEELKA QRQKEEDEKE KDRKKAILFG
     SSDIYDSVQA AEEKVECSHP LDFKEAREVF LVGQNYINES KEYFQLDGHV TDHIEIIQDH
     SSLFKLLAFF EEDYERRCKM HKRRIDMLEP LCKELNPQYY LLICRQLQFE LADTSYEMMD
     LKVAIGNKLD EMDTHTIKKI NSLAQTAIKY YEMFLDSLRS PDQKFPEKLE EDVLRPAMVA
     KFRIARLYGK LISTDGKIQL ENIQKSLNNY KYIVDYCEIN KEAIKCIETE LELSKEMVAL
     LPTRMERLRI QLASFS