ID   5055R_ASFB7             Reviewed;         498 AA.
AC   Q89777;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   23-FEB-2022, entry version 66.
DE   RecName: Full=Protein MGF 505-5R;
GN   OrderedLocusNames=BA71R-028; ORFNames=A498R;
OS   African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS   (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=10498;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA   Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA   Rodriguez J.F., Vinuela E.;
RT   "Analysis of the complete nucleotide sequence of African swine fever
RT   virus.";
RL   Virology 208:249-278(1995).
RN   [2]
RP   FUNCTION.
RX   PubMed=11238833; DOI=10.1128/jvi.75.7.3066-3076.2001;
RA   Zsak L., Lu Z., Burrage T.G., Neilan J.G., Kutish G.F., Moore D.M.,
RA   Rock D.L.;
RT   "African swine fever virus multigene family 360 and 530 genes are novel
RT   macrophage host range determinants.";
RL   J. Virol. 75:3066-3076(2001).
RN   [3]
RP   INDUCTION.
RX   PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA   Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA   Dixon L., Werner F.;
RT   "The African Swine Fever Virus Transcriptome.";
RL   J. Virol. 94:0-0(2020).
CC   -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC       efficient virus replication in macrophages.
CC       {ECO:0000269|PubMed:11238833}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000269|PubMed:32075923}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 505 family. {ECO:0000305}.
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DR   EMBL; U02468; AAA17788.1; -; Genomic_DNA.
DR   EMBL; U18466; AAA65259.1; -; Genomic_DNA.
DR   RefSeq; NP_042723.1; NC_001659.2.
DR   SMR; Q89777; -.
DR   GeneID; 22220411; -.
DR   KEGG; vg:22220411; -.
DR   Proteomes; UP000000624; Genome.
DR   InterPro; IPR004858; MGF_505.
DR   Pfam; PF03158; DUF249; 1.
PE   2: Evidence at transcript level;
KW   Early protein; Reference proteome.
FT   CHAIN           1..498
FT                   /note="Protein MGF 505-5R"
FT                   /id="PRO_0000373332"
SQ   SEQUENCE   498 AA;  58670 MW;  8307F30BC351B277 CRC64;
     MFSLQEICRK NIYFLPDWLS EHVIQRLGLY WEKHGSLQRI GDDYVLIQQD LIIPINEALR
     MAGEEGNDEV VQLLLLWEGN IHYAIIGALE SDHYSLIRKL YDQIEDCHDI LPLIQDPKIF
     EKCHELDKFC NILCLVLHAV KNDMLCILQE YKMHLSGEDI QVVFETACRS QKNDIVSWMG
     QNIAIYNSGV IFDIAFDKMN VSLLSIGYTL LFNHHINNTN ENINSLLTQH LEWAAGMGLL
     HFMLETLKYG GDVTIIVLSE AVKYDHRKIL DYFLRRKNLY QEDLEELLLL AIRADCSKKT
     LNLLLSYLNY SINNIRKKIL QCVKEYETTV IIKILWKRKI NLIEPILADF IGYHSYTYMV
     DFMREFSIHP EKMIKMAARE SREDLIIKFS KKVCKEPKDR LHYLKSLVYT MRHKEGKQLL
     IYTIHNLYKA CHLESKEMFN LARFYARHNA VIQFKSICHD LSKLNINIKN LLLECLGIAI
     KKNYFQLIKT IETDMRYE