ID   KBX32_UROYA             Reviewed;         102 AA.
AC   L0GCW2;
DT   03-SEP-2014, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2013, sequence version 1.
DT   25-MAY-2022, entry version 14.
DE   RecName: Full=Antimicrobial peptide scorpine-like-2;
DE            Short=SCl2;
DE   Flags: Precursor;
OS   Urodacus yaschenkoi (Inland robust scorpion).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Chelicerata; Arachnida;
OC   Scorpiones; Iurida; Scorpionoidea; Scorpionidae; Urodacinae; Urodacus.
OX   NCBI_TaxID=1273102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Venom gland;
RX   PubMed=23182832; DOI=10.1016/j.toxicon.2012.11.017;
RA   Luna-Ramirez K., Quintero-Hernandez V., Vargas-Jaimes L., Batista C.V.,
RA   Winkel K.D., Possani L.D.;
RT   "Characterization of the venom from the Australian scorpion Urodacus
RT   yaschenkoi: molecular mass analysis of components, cDNA sequences and
RT   peptides with antimicrobial activity.";
RL   Toxicon 63:44-54(2013).
CC   -!- FUNCTION: Has antimicrobial activity against yeasts and bacteria.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
CC   -!- SIMILARITY: Belongs to the long chain scorpion toxin family. Class 3
CC       subfamily. {ECO:0000305}.
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DR   EMBL; JX274245; AGA82759.1; -; mRNA.
DR   AlphaFoldDB; L0GCW2; -.
DR   SMR; L0GCW2; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   GO; GO:0050832; P:defense response to fungus; IEA:UniProtKB-KW.
DR   GO; GO:0031640; P:killing of cells of another organism; IEA:UniProtKB-KW.
DR   InterPro; IPR029237; Long_scorpion_toxin.
DR   Pfam; PF14866; Toxin_38; 1.
DR   PROSITE; PS51862; BSPN_CSAB; 1.
PE   2: Evidence at transcript level;
KW   Antibiotic; Antimicrobial; Disulfide bond; Fungicide; Secreted; Signal;
KW   Toxin.
FT   SIGNAL          1..19
FT                   /evidence="ECO:0000255"
FT   CHAIN           20..102
FT                   /note="Antimicrobial peptide scorpine-like-2"
FT                   /id="PRO_5001091947"
FT   DOMAIN          63..102
FT                   /note="BetaSPN-type CS-alpha/beta"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01209"
FT   DISULFID        66..89
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01209"
FT   DISULFID        75..94
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01209"
FT   DISULFID        79..96
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01209"
SQ   SEQUENCE   102 AA;  11274 MW;  0CF7B3D723F874C9 CRC64;
     MQTQCTVLQL LVLVALCSCG GILKEKYFQK GVDYLTSHIP IPVVKDVVKS AAKQLVHKIS
     KNQQLCLIVD TVQWCNKSCL AAENKEGYCH GTKCKCGIKV SY