KCAB_ARATH
ID KCAB_ARATH Reviewed; 328 AA.
AC O23016; Q39151;
DT 22-FEB-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-JAN-1998, sequence version 1.
DT 25-MAY-2022, entry version 135.
DE RecName: Full=Probable voltage-gated potassium channel subunit beta;
DE AltName: Full=K(+) channel subunit beta;
DE AltName: Full=Potassium voltage beta 1;
DE Short=KV-beta1;
GN Name=KAB1; Synonyms=KV-BETA1; OrderedLocusNames=At1g04690;
GN ORFNames=T1G11.6;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=7480329; DOI=10.1104/pp.109.1.327;
RA Tang H., Vasconcelos A.C., Berkowitz G.A.;
RT "Evidence that plant K+ channel proteins have two different types of
RT subunits.";
RL Plant Physiol. 109:327-330(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Columbia;
RA Spoormak P., Palme K.;
RT "Potassium channel beta subunit homolog.";
RL Submitted (APR-1998) to the EMBL/GenBank/DDBJ databases.
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [6]
RP FUNCTION, SUBUNIT, AND TISSUE SPECIFICITY.
RX PubMed=8837508; DOI=10.2307/3870249;
RA Tang H., Vasconcelos A.C., Berkowitz G.A.;
RT "Physical association of KAB1 with plant K+ channel alpha subunits.";
RL Plant Cell 8:1545-1553(1996).
CC -!- FUNCTION: Probable accessory potassium channel protein which modulates
CC the activity of the pore-forming alpha subunit.
CC {ECO:0000269|PubMed:8837508}.
CC -!- SUBUNIT: Forms heteromultimeric complexes with potassium channel alpha
CC subunits. {ECO:0000305|PubMed:8837508}.
CC -!- TISSUE SPECIFICITY: Expressed in roots, leaves and flowers (at protein
CC level). {ECO:0000269|PubMed:8837508}.
CC -!- SIMILARITY: Belongs to the shaker potassium channel beta subunit
CC family. {ECO:0000305}.
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DR EMBL; L40948; AAA87294.1; -; mRNA.
DR EMBL; AF061570; AAC15999.1; -; mRNA.
DR EMBL; AC002376; AAB80621.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE27734.1; -; Genomic_DNA.
DR EMBL; AY050821; AAK92756.1; -; mRNA.
DR EMBL; AY091424; AAM14363.1; -; mRNA.
DR PIR; T52133; T52133.
DR RefSeq; NP_171963.1; NM_100349.4.
DR AlphaFoldDB; O23016; -.
DR SMR; O23016; -.
DR BioGRID; 24685; 4.
DR IntAct; O23016; 2.
DR STRING; 3702.AT1G04690.1; -.
DR PaxDb; O23016; -.
DR PRIDE; O23016; -.
DR ProteomicsDB; 232245; -.
DR EnsemblPlants; AT1G04690.1; AT1G04690.1; AT1G04690.
DR GeneID; 839450; -.
DR Gramene; AT1G04690.1; AT1G04690.1; AT1G04690.
DR KEGG; ath:AT1G04690; -.
DR Araport; AT1G04690; -.
DR TAIR; locus:2197793; AT1G04690.
DR eggNOG; KOG1575; Eukaryota.
DR HOGENOM; CLU_023205_2_0_1; -.
DR InParanoid; O23016; -.
DR OMA; YSMINRW; -.
DR OrthoDB; 1106773at2759; -.
DR PhylomeDB; O23016; -.
DR PRO; PR:O23016; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; O23016; baseline and differential.
DR Genevisible; O23016; AT.
DR GO; GO:0005576; C:extracellular region; HDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; HDA:TAIR.
DR GO; GO:0009506; C:plasmodesma; HDA:TAIR.
DR GO; GO:0005244; F:voltage-gated ion channel activity; IEA:UniProtKB-KW.
DR GO; GO:0006813; P:potassium ion transport; IEA:UniProtKB-KW.
DR GO; GO:0034765; P:regulation of ion transmembrane transport; IEA:UniProtKB-KW.
DR Gene3D; 3.20.20.100; -; 1.
DR InterPro; IPR005399; K_chnl_volt-dep_bsu_KCNAB-rel.
DR InterPro; IPR023210; NADP_OxRdtase_dom.
DR InterPro; IPR036812; NADP_OxRdtase_dom_sf.
DR PANTHER; PTHR43150; PTHR43150; 1.
DR Pfam; PF00248; Aldo_ket_red; 1.
DR PRINTS; PR01577; KCNABCHANNEL.
DR SUPFAM; SSF51430; SSF51430; 1.
PE 1: Evidence at protein level;
KW Ion channel; Ion transport; Potassium; Potassium transport;
KW Reference proteome; Transport; Voltage-gated channel.
FT CHAIN 1..328
FT /note="Probable voltage-gated potassium channel subunit
FT beta"
FT /id="PRO_0000415614"
FT CONFLICT 133
FT /note="T -> A (in Ref. 1; AAA87294)"
FT /evidence="ECO:0000305"
FT CONFLICT 151
FT /note="T -> I (in Ref. 1; AAA87294)"
FT /evidence="ECO:0000305"
FT CONFLICT 259
FT /note="D -> G (in Ref. 1; AAA87294)"
FT /evidence="ECO:0000305"
FT CONFLICT 289
FT /note="E -> G (in Ref. 1; AAA87294)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 328 AA; 36539 MW; 5FAE34A3BA100ED0 CRC64;
MQYKNLGKSG LKVSTLSFGA WVTFGNQLDV KEAKSILQCC RDHGVNFFDN AEVYANGRAE
EIMGQAIREL GWRRSDIVIS TKIFWGGPGP NDKGLSRKHI VEGTKASLKR LDMDYVDVLY
CHRPDASTPI EETVRAMNYV IDKGWAFYWG TSEWSAQQIT EAWGAADRLD LVGPIVEQPE
YNMFARHKVE TEFLPLYTNH GIGLTTWSPL ASGVLTGKYN KGAIPSDSRF ALENYKNLAN
RSLVDDVLRK VSGLKPIADE LGVTLAQLAI AWCASNPNVS SVITGATRES QIQENMKAVD
VIPLLTPIVL DKIEQVIQSK PKRPESYR
