KCAI_ARATH
ID KCAI_ARATH Reviewed; 920 AA.
AC F4JUQ2; F4JUQ1; O23289;
DT 30-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 1.
DT 25-MAY-2022, entry version 67.
DE RecName: Full=KIN14B-interacting protein At4g14310;
GN OrderedLocusNames=At4g14310 {ECO:0000312|Araport:AT4G14310};
GN ORFNames=dl3195c {ECO:0000312|EMBL:CAB10210.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702 {ECO:0000312|Proteomes:UP000006548};
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=9461215; DOI=10.1038/35140;
RA Bevan M., Bancroft I., Bent E., Love K., Goodman H.M., Dean C.,
RA Bergkamp R., Dirkse W., van Staveren M., Stiekema W., Drost L., Ridley P.,
RA Hudson S.-A., Patel K., Murphy G., Piffanelli P., Wedler H., Wedler E.,
RA Wambutt R., Weitzenegger T., Pohl T., Terryn N., Gielen J., Villarroel R.,
RA De Clercq R., van Montagu M., Lecharny A., Aubourg S., Gy I., Kreis M.,
RA Lao N., Kavanagh T., Hempel S., Kotter P., Entian K.-D., Rieger M.,
RA Schaefer M., Funk B., Mueller-Auer S., Silvey M., James R., Monfort A.,
RA Pons A., Puigdomenech P., Douka A., Voukelatou E., Milioni D.,
RA Hatzopoulos P., Piravandi E., Obermaier B., Hilbert H., Duesterhoeft A.,
RA Moores T., Jones J.D.G., Eneva T., Palme K., Benes V., Rechmann S.,
RA Ansorge W., Cooke R., Berger C., Delseny M., Voet M., Volckaert G.,
RA Mewes H.-W., Klosterman S., Schueller C., Chalwatzis N.;
RT "Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis
RT thaliana.";
RL Nature 391:485-488(1998).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP FUNCTION, INTERACTION WITH KIN14B; CDKA-1; CKS1 AND CKS2, AND SUBCELLULAR
RP LOCATION.
RX PubMed=20706207; DOI=10.1038/msb.2010.53;
RA Van Leene J., Hollunder J., Eeckhout D., Persiau G., Van De Slijke E.,
RA Stals H., Van Isterdael G., Verkest A., Neirynck S., Buffel Y., De Bodt S.,
RA Maere S., Laukens K., Pharazyn A., Ferreira P.C.G., Eloy N., Renne C.,
RA Meyer C., Faure J.-D., Steinbrenner J., Beynon J., Larkin J.C.,
RA Van de Peer Y., Hilson P., Kuiper M., De Veylder L., Van Onckelen H.,
RA Inze D., Witters E., De Jaeger G.;
RT "Targeted interactomics reveals a complex core cell cycle machinery in
RT Arabidopsis thaliana.";
RL Mol. Syst. Biol. 6:397-397(2010).
CC -!- FUNCTION: Might be involved in division plane determination.
CC {ECO:0000305|PubMed:20706207}.
CC -!- SUBUNIT: Interacts with KIN14B, CDKA-1, CKS1 and CKS2.
CC {ECO:0000269|PubMed:20706207}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:20706207}.
CC Note=Localizes at the pre-prophase band. {ECO:0000269|PubMed:20706207}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=F4JUQ2-1; Sequence=Displayed;
CC Name=2;
CC IsoId=F4JUQ2-2; Sequence=VSP_058667;
CC -!- SEQUENCE CAUTION:
CC Sequence=CAB10210.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=CAB78473.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; Z97335; CAB10210.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161538; CAB78473.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE83415.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE83416.1; -; Genomic_DNA.
DR PIR; H71404; H71404.
DR RefSeq; NP_193167.3; NM_117508.4. [F4JUQ2-2]
DR RefSeq; NP_849378.2; NM_179047.2. [F4JUQ2-1]
DR AlphaFoldDB; F4JUQ2; -.
DR IntAct; F4JUQ2; 13.
DR STRING; 3702.AT4G14310.2; -.
DR iPTMnet; F4JUQ2; -.
DR PaxDb; F4JUQ2; -.
DR PRIDE; F4JUQ2; -.
DR ProteomicsDB; 250619; -. [F4JUQ2-1]
DR EnsemblPlants; AT4G14310.1; AT4G14310.1; AT4G14310. [F4JUQ2-2]
DR EnsemblPlants; AT4G14310.2; AT4G14310.2; AT4G14310. [F4JUQ2-1]
DR GeneID; 827072; -.
DR Gramene; AT4G14310.1; AT4G14310.1; AT4G14310. [F4JUQ2-2]
DR Gramene; AT4G14310.2; AT4G14310.2; AT4G14310. [F4JUQ2-1]
DR KEGG; ath:AT4G14310; -.
DR Araport; AT4G14310; -.
DR TAIR; locus:2129610; AT4G14310.
DR eggNOG; ENOG502QUEI; Eukaryota.
DR HOGENOM; CLU_012519_1_0_1; -.
DR InParanoid; F4JUQ2; -.
DR OMA; WDYYSRE; -.
DR OrthoDB; 515127at2759; -.
DR PhylomeDB; F4JUQ2; -.
DR PRO; PR:F4JUQ2; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; F4JUQ2; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR Gene3D; 2.130.10.10; -; 1.
DR InterPro; IPR045289; At4g14310-like.
DR InterPro; IPR011044; Quino_amine_DH_bsu.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR35492; PTHR35492; 1.
DR SUPFAM; SSF50969; SSF50969; 2.
PE 1: Evidence at protein level;
KW Alternative splicing; Cell cycle; Cell division; Coiled coil; Cytoplasm;
KW Reference proteome.
FT CHAIN 1..920
FT /note="KIN14B-interacting protein At4g14310"
FT /id="PRO_0000438503"
FT REGION 1..199
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 309..375
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 435..463
FT /evidence="ECO:0000255"
FT COMPBIAS 1..67
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 110..133
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 134..151
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 164..183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..341
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 508..534
FT /note="Missing (in isoform 2)"
FT /id="VSP_058667"
SQ SEQUENCE 920 AA; 100474 MW; 0CC80EC365CDC6F9 CRC64;
MSASTNRRRL KDINTGAGEN PSSGKKPLRS VTPLPISSKN SNPALQKSLS SKENPNPKLS
HRSFGSTQKP VLRPVPRIDK SAVSGEGRVT RSTSSGLRGR SSSPSDLIRV FSDLRKRNES
RVIGEKGESG QDKKSGLKSS GFKQGTSEIK VEPSSVCEKA DEGSSCPVNS SKFEGSSVAR
NSISDPKAHA LVGSGEKSTV ALKSDSKIEK TGKGTSVALR RKSLDNVGKA MEMSKDIRGN
EGSSNSTAKY PSKLHEKLAF LEGKVKKIAS DIKKTKDMLD LNNPDSSKVI ISDIHQKITG
IEKSMSHVID GPEKNKTTKA KSSVKGLNKE ELEDRLLPHQ RLLRSRTQSK TSSHVSKGHD
SVESNKAVNA EEKPSAPVEE NAIALEFLAS LDKEKVTFMS DQNALENLEV QEMDTEEPSK
ENDVSKDVNL TSNLTEILRA NEALEEIDDE ENREEMELEE IDDGCMYQLN DIGSKTSTGG
WFVSEGEAVI LAHDDGSCSY YDVANSEFMV NECNSLSIWV RLYEVTGVFG FVHYVKSVYS
PPDGISPNTW RDCWVVRAPG ADGCSGRYVV AASAGNTLES GFCSWDFYTK DIKALHIEDG
SSRVSRTALA PLPNNTSHGR NTPACAVVPE TQQWWYRPCG PLIASTGSFQ SIVKVFDIRD
GEQIMKWGVQ NPVSALDYSS PLQWRNRGKL VIAETEAISV WDVNSLHPEA QHTISSSGRK
ISAFHINNTD AEVGGGVRQR VSSLDAEGND GVFCTSDSIN ILDFRNPSGI GAKIPKLGVN
AQCVSSRGDS VFLGCTNQKS TVKKQMASSS QVQQFSIRKQ RLVSTYSLPD SNSHPHHSAI
TQVWGNSNFV MATSGMGLFV FDTAKEETLQ QQPLTSDYGS VQTVREIIGP NDMYCPSFDY
SGCRVLLISR DRPALWRYLL
