1105L_ASFPP
ID 1105L_ASFPP Reviewed; 124 AA.
AC A9JLI7;
DT 23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT 05-FEB-2008, sequence version 1.
DT 03-AUG-2022, entry version 17.
DE RecName: Full=Protein MGF 110-5L;
DE Flags: Precursor;
GN Name=MGF 110-5L {ECO:0000312|EMBL:CAN10359.1};
OS African swine fever virus (isolate Pig/Portugal/OURT88/1988) (ASFV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Asfuvirales; Asfarviridae; Asfivirus.
OX NCBI_TaxID=443878;
OH NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=OURT 88/3 {ECO:0000312|EMBL:CAN10359.1};
RX PubMed=18198370; DOI=10.1099/vir.0.83343-0;
RA Chapman D.A.G., Tcherepanov V., Upton C., Dixon L.K.;
RT "Comparison of the genome sequences of non-pathogenic and pathogenic
RT African swine fever virus isolates.";
RL J. Gen. Virol. 89:397-408(2008).
RN [2]
RP SIGNAL SEQUENCE CLEAVAGE SITE.
RX PubMed=30279544; DOI=10.1038/s41598-018-32985-z;
RA Kessler C., Forth J.H., Keil G.M., Mettenleiter T.C., Blome S., Karger A.;
RT "The intracellular proteome of African swine fever virus.";
RL Sci. Rep. 8:14714-14714(2018).
CC -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC efficient virus replication in macrophages. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the asfivirus MGF 110 family. {ECO:0000305}.
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DR EMBL; AM712240; CAN10359.1; -; Genomic_DNA.
DR Proteomes; UP000108903; Genome.
DR InterPro; IPR004848; ASFV_fam_110.
DR Pfam; PF01639; v110; 1.
PE 1: Evidence at protein level;
KW Early protein; Signal.
FT SIGNAL 1..28
FT /evidence="ECO:0000269|PubMed:30279544"
FT CHAIN 29..124
FT /note="Protein MGF 110-5L"
FT /id="PRO_0000454843"
SQ SEQUENCE 124 AA; 14178 MW; 65C2136FAE72BC22 CRC64;
MLVIILGVIG LLANQVLGLP TQAGGHLRST DNPPQEELGY WCTYMESCKF CWECAHGICK
NKVNESMPLI IENSYLTSCE VSRWYNQCTY SEGNGHYHVM DCSDPVPHNR PHRLLMKIYE
KEDL