ID   KCD15_XENTR             Reviewed;         255 AA.
AC   Q6P3P4;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=BTB/POZ domain-containing protein kctd15;
DE   AltName: Full=Potassium channel tetramerization domain-containing protein 15;
GN   Name=kctd15;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: During embryonic development, interferes with neural crest
CC       formation. Inhibits AP2 transcriptional activity by interaction with
CC       its activation domain (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with TFAP2A; this interaction inhibits TFAP2A
CC       transcriptional activation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:Q8K0E1}.
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DR   EMBL; BC063913; AAH63913.1; -; mRNA.
DR   RefSeq; NP_989239.1; NM_203908.1.
DR   RefSeq; XP_012816219.1; XM_012960765.2.
DR   RefSeq; XP_017948462.1; XM_018092973.1.
DR   AlphaFoldDB; Q6P3P4; -.
DR   SMR; Q6P3P4; -.
DR   STRING; 8364.ENSXETP00000061753; -.
DR   PaxDb; Q6P3P4; -.
DR   DNASU; 394848; -.
DR   GeneID; 394848; -.
DR   KEGG; xtr:394848; -.
DR   CTD; 79047; -.
DR   Xenbase; XB-GENE-944069; kctd15.
DR   eggNOG; KOG2723; Eukaryota.
DR   HOGENOM; CLU_061268_1_0_1; -.
DR   InParanoid; Q6P3P4; -.
DR   OrthoDB; 971350at2759; -.
DR   PhylomeDB; Q6P3P4; -.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000016868; Expressed in gastrula and 3 other tissues.
DR   ExpressionAtlas; Q6P3P4; baseline.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   CDD; cd18388; BTB_POZ_KCTD15; 1.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR045904; KCTD15_T1-type_BTB.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR003131; T1-type_BTB.
DR   Pfam; PF02214; BTB_2; 1.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Nucleus; Reference proteome.
FT   CHAIN           1..255
FT                   /note="BTB/POZ domain-containing protein kctd15"
FT                   /id="PRO_0000247256"
FT   DOMAIN          30..100
FT                   /note="BTB"
SQ   SEQUENCE   255 AA;  29251 MW;  30705D24AD6B65A1 CRC64;
     MSRLSLTRSP VSPLAAQGIP LPAQLTKSNA PVHIDVGGHM YTSSLATLTK YPDSRISRLF
     NGTEPIVLDS LKQHYFIDRD GEIFRYILSF LRTSKLLLPE DFKEFNLLYE EAKYYQLHPM
     VKELERWKQD KEHRKHFQPC DCLVVRVTPD LGERIALSGE KALIEEIFPE TGDVMCNSVN
     AGWNQDPTHV IRFPLNGYCR LNSVQVLERM FQKGFHVAAS CGGGVDSSQF SEYVLCREDR
     RMQPNTMRIK QEPLD