ID   KCP1_BRANA              Reviewed;         215 AA.
AC   Q84U09;
DT   23-FEB-2022, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 39.
DE   RecName: Full=KID-containing protein 1 {ECO:0000303|PubMed:12631331};
DE            Short=BnKCP1 {ECO:0000303|PubMed:12631331};
GN   Name=KCP1 {ECO:0000303|PubMed:12631331};
GN   ORFNames=DARMORV10_A02P40050.1 {ECO:0000312|EMBL:CAF2144644.1};
OS   Brassica napus (Rape).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Brassiceae; Brassica.
OX   NCBI_TaxID=3708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, MUTAGENESIS OF SER-188, INTERACTION
RP   WITH HDA19, SUBCELLULAR LOCATION, TISSUE SPECIFICITY, INDUCTION BY COLD,
RP   PHOSPHORYLATION AT SER-188, AND DOMAIN.
RX   PubMed=12631331; DOI=10.1046/j.1365-313x.2003.01694.x;
RA   Gao M.-J., Schaefer U.A., Parkin I.A.P., Hegedus D.D., Lydiate D.J.,
RA   Hannoufa A.;
RT   "A novel protein from Brassica napus has a putative KID domain and responds
RT   to low temperature.";
RL   Plant J. 33:1073-1086(2003).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Genoscope - CEA;
RA   William W.;
RL   Submitted (JAN-2021) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Transcription activator which may regulates gene expression
CC       through interaction with the histone deacetylase HDA19.
CC       {ECO:0000269|PubMed:12631331}.
CC   -!- SUBUNIT: Interacts with HDA19; Ser-188 is critical for this
CC       interaction. {ECO:0000269|PubMed:12631331}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:12631331}.
CC   -!- TISSUE SPECIFICITY: Strongly expressed in stems, flowers, roots and
CC       immature siliques, but not detected in leaf blades of seedlings.
CC       {ECO:0000269|PubMed:12631331}.
CC   -!- INDUCTION: Accumulates in leaf blades but fades out from stems in
CC       response to cold stress (PubMed:12631331). Rapid but transient
CC       induction in leaf blades in response to inomycin, an ionophore of
CC       Ca(2+), suggesting a transient Ca(2+) influx (PubMed:12631331).
CC       {ECO:0000269|PubMed:12631331}.
CC   -!- DOMAIN: The Kinase-inducible domain (KID, 177-204) is required for
CC       interaction with HDA19. {ECO:0000269|PubMed:12631331}.
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DR   EMBL; AY211985; AAO53442.1; -; mRNA.
DR   EMBL; HG994356; CAF2144644.1; -; Genomic_DNA.
DR   RefSeq; NP_001302889.1; NM_001315960.1.
DR   EnsemblPlants; CDY05462; CDY05462; GSBRNA2T00120377001.
DR   GeneID; 106404212; -.
DR   Gramene; CDY05462; CDY05462; GSBRNA2T00120377001.
DR   KEGG; bna:106404212; -.
DR   OMA; LMASKWS; -.
DR   GO; GO:0005634; C:nucleus; IDA:UniProtKB.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IDA:UniProtKB.
DR   GO; GO:0009409; P:response to cold; IEP:UniProtKB.
PE   1: Evidence at protein level;
KW   Activator; Nucleus; Phosphoprotein; Stress response; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..215
FT                   /note="KID-containing protein 1"
FT                   /id="PRO_0000455038"
FT   REGION          1..132
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          150..183
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          177..204
FT                   /note="Kinase-inducible domain (KID)"
FT                   /evidence="ECO:0000303|PubMed:12631331"
FT   MOTIF           129..137
FT                   /note="Nuclear localization signal"
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        46..62
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        63..80
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..106
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        162..176
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   SITE            188
FT                   /note="Critical for interaction with HDA19"
FT                   /evidence="ECO:0000269|PubMed:12631331"
FT   MOD_RES         188
FT                   /note="Phosphoserine; by PKA"
FT                   /evidence="ECO:0000269|PubMed:12631331"
FT   MUTAGEN         188
FT                   /note="S->G: Impaired inte3raction with HDA19."
FT                   /evidence="ECO:0000269|PubMed:12631331"
SQ   SEQUENCE   215 AA;  23505 MW;  0BCF45C2434E1FC0 CRC64;
     MAGGGPTFSI ELSAYGSDLP TDKASGDIPN EEGSGLSRVG SGIWSGRTVD YSSESSSSIG
     TPGDSEEEDE ESEEDNDEEE LGLASLRSLE DSLPSKGLSS HYKGKSKSFG NLGEIGSVKE
     VPKQENPLNK KRRLQIYNKL ARKSFYSWQN PKSMPLLPVH EDNDDEEGDD GDLSDEERGG
     DVLARRPSFK NRALKSMSCF ALSDLQEEEE EEEDE