ID   KCTD7_BOVIN             Reviewed;         289 AA.
AC   A4IFB4;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2007, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=BTB/POZ domain-containing protein KCTD7;
GN   Name=KCTD7;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Ascending colon;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (MAR-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May be involved in the control of excitability of cortical
CC       neurons. {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with CUL3. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}. Cytoplasm, cytosol
CC       {ECO:0000250}.
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DR   EMBL; BC134499; AAI34500.1; -; mRNA.
DR   RefSeq; NP_001096015.1; NM_001102545.1.
DR   AlphaFoldDB; A4IFB4; -.
DR   SMR; A4IFB4; -.
DR   STRING; 9913.ENSBTAP00000023179; -.
DR   PaxDb; A4IFB4; -.
DR   PRIDE; A4IFB4; -.
DR   Ensembl; ENSBTAT00000023179; ENSBTAP00000023179; ENSBTAG00000017435.
DR   GeneID; 100124502; -.
DR   KEGG; bta:100124502; -.
DR   CTD; 154881; -.
DR   VEuPathDB; HostDB:ENSBTAG00000017435; -.
DR   VGNC; VGNC:30515; KCTD7.
DR   eggNOG; KOG2723; Eukaryota.
DR   GeneTree; ENSGT00940000161327; -.
DR   InParanoid; A4IFB4; -.
DR   OMA; PFQFPEV; -.
DR   OrthoDB; 1377258at2759; -.
DR   Proteomes; UP000009136; Chromosome 25.
DR   Bgee; ENSBTAG00000017435; Expressed in pons and 103 other tissues.
DR   ExpressionAtlas; A4IFB4; baseline and differential.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0060081; P:membrane hyperpolarization; IBA:GO_Central.
DR   GO; GO:0032411; P:positive regulation of transporter activity; IBA:GO_Central.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR003131; T1-type_BTB.
DR   Pfam; PF02214; BTB_2; 1.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Cytoplasm; Membrane; Reference proteome.
FT   CHAIN           1..289
FT                   /note="BTB/POZ domain-containing protein KCTD7"
FT                   /id="PRO_0000369239"
FT   DOMAIN          53..141
FT                   /note="BTB"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   289 AA;  33138 MW;  B520974FB3614D98 CRC64;
     MVVVTGREPD SRRPDGAMSS SDAEDDFLEP ATPTATQAGH SLPLLPQEFP EVVPLNIGGA
     HFTTRLSTLR RYEDTMLAAM FSGRHYIPTD AEGRYFIDRD GAHFGDVLNF LRSGDLPPRE
     RVRAVYKEAQ YYAIGPLLEQ LENMQPLKGE KVRQAFLGLM PYYKDHLERI VEIARLRAVQ
     RKARFAKLKV CVFKEEMPIT PYECPLLNSL RFERSESDGQ LFEHHCEVDV SFGPWEAVAD
     VYDLLHCLVT DLSAQGLTVD HQCIGVCDKH LINHYYCKRP IYEFKITWW