ID   KCTD7_CHICK             Reviewed;         289 AA.
AC   Q5ZJP7;
DT   03-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   23-NOV-2004, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=BTB/POZ domain-containing protein KCTD7;
GN   Name=KCTD7; ORFNames=RCJMB04_16j10;
OS   Gallus gallus (Chicken).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC   Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC   Phasianinae; Gallus.
OX   NCBI_TaxID=9031;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=CB; TISSUE=Bursa of Fabricius;
RX   PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA   Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA   Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA   Hayashizaki Y., Buerstedde J.-M.;
RT   "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT   function analysis.";
RL   Genome Biol. 6:R6.1-R6.9(2005).
CC   -!- FUNCTION: May be involved in the control of excitability of cortical
CC       neurons. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}. Cytoplasm, cytosol
CC       {ECO:0000250}.
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DR   EMBL; AJ720387; CAG32046.1; -; mRNA.
DR   RefSeq; NP_001034358.1; NM_001039269.1.
DR   AlphaFoldDB; Q5ZJP7; -.
DR   SMR; Q5ZJP7; -.
DR   STRING; 9031.ENSGALP00000004111; -.
DR   PaxDb; Q5ZJP7; -.
DR   PRIDE; Q5ZJP7; -.
DR   Ensembl; ENSGALT00000004120; ENSGALP00000004111; ENSGALG00000002618.
DR   GeneID; 417547; -.
DR   KEGG; gga:417547; -.
DR   CTD; 154881; -.
DR   VEuPathDB; HostDB:geneid_417547; -.
DR   eggNOG; KOG2723; Eukaryota.
DR   GeneTree; ENSGT00940000161327; -.
DR   HOGENOM; CLU_070345_1_0_1; -.
DR   InParanoid; Q5ZJP7; -.
DR   OMA; PFQFPEV; -.
DR   OrthoDB; 1377258at2759; -.
DR   PhylomeDB; Q5ZJP7; -.
DR   TreeFam; TF315332; -.
DR   Reactome; R-GGA-8951664; Neddylation.
DR   Reactome; R-GGA-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR   PRO; PR:Q5ZJP7; -.
DR   Proteomes; UP000000539; Chromosome 19.
DR   Bgee; ENSGALG00000002618; Expressed in spermatid and 13 other tissues.
DR   ExpressionAtlas; Q5ZJP7; baseline and differential.
DR   GO; GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0060081; P:membrane hyperpolarization; IBA:GO_Central.
DR   GO; GO:0032411; P:positive regulation of transporter activity; IBA:GO_Central.
DR   GO; GO:0051260; P:protein homooligomerization; IEA:InterPro.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   InterPro; IPR003131; T1-type_BTB.
DR   Pfam; PF02214; BTB_2; 1.
DR   SMART; SM00225; BTB; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
PE   2: Evidence at transcript level;
KW   Cell membrane; Cytoplasm; Membrane; Reference proteome.
FT   CHAIN           1..289
FT                   /note="BTB/POZ domain-containing protein KCTD7"
FT                   /id="PRO_0000251475"
FT   DOMAIN          51..149
FT                   /note="BTB"
FT   REGION          1..35
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   289 AA;  33228 MW;  EDA89D0E2622567C CRC64;
     MVVVTGQSKG SGDPDEAMSS SDAEDDFQEP ATPTATQAGQ ALPLLPQQFP EVVPLNVGGM
     HFTTRLSTLR RYEDTMLAAM FSGRHYIPTD AEGRYFIDRD GTYFGDILNF LRSGDLPPRE
     RVRPVYKEAQ YYSIGPLLDH LEDVQPLKGE KVRQAFLGLM PYYKDHLERI IEIAKLRAVQ
     RKARFAKLKV CVFKEEMPIT PYECPHFNSL RFERSESEAK LFEHHCEVDV SFGPWEAVAD
     VYDLLHCIVT DLSDRGITVD HQCIGVCDKH LINHYYCKRP IYEFKITWW