5059R_ASFB7
ID 5059R_ASFB7 Reviewed; 506 AA.
AC Q89740;
DT 05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 23-FEB-2022, entry version 68.
DE RecName: Full=Protein MGF 505-9R;
GN OrderedLocusNames=BA71R-030; ORFNames=A506R;
OS African swine fever virus (strain Badajoz 1971 Vero-adapted) (Ba71V)
OS (ASFV).
OC Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC Asfuvirales; Asfarviridae; Asfivirus.
OX NCBI_TaxID=10498;
OH NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH NCBI_TaxID=9823; Sus scrofa (Pig).
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=11831707; DOI=10.1006/viro.1995.1149;
RA Yanez R.J., Rodriguez J.M., Nogal M.L., Yuste L., Enriquez C.,
RA Rodriguez J.F., Vinuela E.;
RT "Analysis of the complete nucleotide sequence of African swine fever
RT virus.";
RL Virology 208:249-278(1995).
RN [2]
RP FUNCTION.
RX PubMed=11238833; DOI=10.1128/jvi.75.7.3066-3076.2001;
RA Zsak L., Lu Z., Burrage T.G., Neilan J.G., Kutish G.F., Moore D.M.,
RA Rock D.L.;
RT "African swine fever virus multigene family 360 and 530 genes are novel
RT macrophage host range determinants.";
RL J. Virol. 75:3066-3076(2001).
RN [3]
RP INDUCTION.
RX PubMed=32075923; DOI=10.1128/jvi.00119-20;
RA Cackett G., Matelska D., Sykora M., Portugal R., Malecki M., Baehler J.,
RA Dixon L., Werner F.;
RT "The African Swine Fever Virus Transcriptome.";
RL J. Virol. 94:0-0(2020).
CC -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC efficient virus replication in macrophages.
CC {ECO:0000269|PubMed:11238833}.
CC -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC {ECO:0000269|PubMed:32075923}.
CC -!- SIMILARITY: Belongs to the asfivirus MGF 505 family. {ECO:0000305}.
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DR EMBL; U02468; AAA17790.1; -; Genomic_DNA.
DR EMBL; U18466; AAA65261.1; -; Genomic_DNA.
DR RefSeq; NP_042725.1; NC_001659.2.
DR SMR; Q89740; -.
DR GeneID; 22220413; -.
DR KEGG; vg:22220413; -.
DR Proteomes; UP000000624; Genome.
DR InterPro; IPR004858; MGF_505.
DR Pfam; PF03158; DUF249; 1.
PE 2: Evidence at transcript level;
KW Early protein; Reference proteome.
FT CHAIN 1..506
FT /note="Protein MGF 505-9R"
FT /id="PRO_0000373344"
SQ SEQUENCE 506 AA; 59402 MW; C26CD9DBAE6E2CFC CRC64;
MFSLQDLCRK NLFLPLEPLG KHVVQRLGLY WEGHGSLKRV GDCFICVDKI WILSIHKAIQ
IAASEGNENI VKLFLLWKGS LQYAIIGALE GRQYDLIQKY YNQIGDCHEN LPLIQDPEIY
ERCHELNVTC TFQCLFQHAI RDNMLPIFQK YGEDLNGNRR MVQLLYEMAC RLQNYDIIKW
IGFNLHVYNL EAIFSIAFVR KDLTLYSLGY MLLLGRMSTE DRNFISIITR HLEYASKKGL
FDFVLESLKY GGQVDTVLFQ AVKYNHRKIL AHFIHEIPRE TVEKLILHAV ESRASRKTFN
LLLSSINYCV NPFVKKLLHT VVKHKYMLII KLLLERPKKK INLVDAALFK LVKYSTYAEI
VKFMKEFSVD PERVVKMAAR LMRVDLIKKI SNDAWENKLE RIKHLKQMVN TMNHRNGKNL
LMYNIHNITG YTCLNTKEAF NLTRFYAVHN ATCLFKEMCK SCFVHDKIQF RELLEDCLHI
ANRHDYIQIA ETADECIKYI DLITPK