ID   KDGT2_SALTY             Reviewed;         317 AA.
AC   Q8ZQZ4;
DT   03-APR-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   03-AUG-2022, entry version 96.
DE   RecName: Full=2-keto-3-deoxygluconate permease 2;
DE            Short=KDG permease 2;
GN   Name=kdgT2; OrderedLocusNames=STM0651;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: The 2-keto-3-deoxygluconate permease transports the degraded
CC       pectin products into the bacterial cell, where they serve as carbon and
CC       energy sources. This is a hydrogen coupled transport system (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the KdgT transporter family. {ECO:0000305}.
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DR   EMBL; AE006468; AAL19602.1; -; Genomic_DNA.
DR   RefSeq; NP_459643.1; NC_003197.2.
DR   RefSeq; WP_000694477.1; NC_003197.2.
DR   AlphaFoldDB; Q8ZQZ4; -.
DR   STRING; 99287.STM0651; -.
DR   PaxDb; Q8ZQZ4; -.
DR   EnsemblBacteria; AAL19602; AAL19602; STM0651.
DR   GeneID; 1252171; -.
DR   KEGG; stm:STM0651; -.
DR   PATRIC; fig|99287.12.peg.687; -.
DR   HOGENOM; CLU_057476_0_0_6; -.
DR   OMA; QYGDARD; -.
DR   PhylomeDB; Q8ZQZ4; -.
DR   BioCyc; SENT99287:STM0651-MON; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015649; F:2-keto-3-deoxygluconate:proton symporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00070; KdgT; 1.
DR   InterPro; IPR004684; 2keto-3dGluconate_permease.
DR   Pfam; PF03812; KdgT; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Sugar transport; Symport; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..317
FT                   /note="2-keto-3-deoxygluconate permease 2"
FT                   /id="PRO_0000209683"
FT   TOPO_DOM        1..9
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        31..34
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        35..55
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        56..73
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        74..94
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        95..104
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        105..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        126..132
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        133..153
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        154..157
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        158..178
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        179..190
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        191..211
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        212..213
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        235..248
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        249..269
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        270..281
FT                   /note="Periplasmic"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        282..302
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TOPO_DOM        303..317
FT                   /note="Cytoplasmic"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   317 AA;  32366 MW;  5030EC93A043ADAA CRC64;
     MKIKKTLERF PGGMMVVPLI IGALFKTFAP EALEIGGFVT SISHGAMAIL GMFLVCMGAD
     IQFKAAPKAL KKGAAITFAK FASGVIIGIL VGKFCGPDGL LGLSALAIIS AMTNSNSGLY
     AALVGEYGDE TDGGAIAVIS LNDGPFFTML ALGSAGMVSI PFMNLVAVII PIIIGMILGN
     LDEDMRKFLK QGSVVTIPFF AFGLGYGIDF ARLITAGSSG ILLGLMTVAI GGFFNIFADR
     LTGGSGVAGA AVSTTSGNAV ATPAAIALLD PHFTDLASTA AAQVAASTII TALCAPFLTV
     WIKKRYDRKL NPAAAGG