ID   KDGT_CARHZ              Reviewed;         320 AA.
AC   Q3ACP3;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=2-keto-3-deoxygluconate permease {ECO:0000255|HAMAP-Rule:MF_00070};
DE            Short=KDG permease {ECO:0000255|HAMAP-Rule:MF_00070};
GN   Name=kdgT {ECO:0000255|HAMAP-Rule:MF_00070}; OrderedLocusNames=CHY_1257;
OS   Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 /
OS   Z-2901).
OC   Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteraceae; Carboxydothermus.
OX   NCBI_TaxID=246194;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-161 / DSM 6008 / Z-2901;
RX   PubMed=16311624; DOI=10.1371/journal.pgen.0010065;
RA   Wu M., Ren Q., Durkin A.S., Daugherty S.C., Brinkac L.M., Dodson R.J.,
RA   Madupu R., Sullivan S.A., Kolonay J.F., Nelson W.C., Tallon L.J.,
RA   Jones K.M., Ulrich L.E., Gonzalez J.M., Zhulin I.B., Robb F.T., Eisen J.A.;
RT   "Life in hot carbon monoxide: the complete genome sequence of
RT   Carboxydothermus hydrogenoformans Z-2901.";
RL   PLoS Genet. 1:563-574(2005).
CC   -!- FUNCTION: The 2-keto-3-deoxygluconate permease transports the degraded
CC       pectin products into the bacterial cell, where they serve as carbon and
CC       energy sources. This is a hydrogen coupled transport system.
CC       {ECO:0000255|HAMAP-Rule:MF_00070}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000255|HAMAP-Rule:MF_00070};
CC       Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00070}.
CC   -!- SIMILARITY: Belongs to the KdgT transporter family. {ECO:0000255|HAMAP-
CC       Rule:MF_00070}.
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DR   EMBL; CP000141; ABB14994.1; -; Genomic_DNA.
DR   RefSeq; WP_011344167.1; NC_007503.1.
DR   AlphaFoldDB; Q3ACP3; -.
DR   SMR; Q3ACP3; -.
DR   STRING; 246194.CHY_1257; -.
DR   EnsemblBacteria; ABB14994; ABB14994; CHY_1257.
DR   KEGG; chy:CHY_1257; -.
DR   eggNOG; ENOG502Z7JT; Bacteria.
DR   HOGENOM; CLU_057476_0_1_9; -.
DR   OMA; YASLMNQ; -.
DR   OrthoDB; 1029737at2; -.
DR   Proteomes; UP000002706; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015649; F:2-keto-3-deoxygluconate:proton symporter activity; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00070; KdgT; 1.
DR   InterPro; IPR004684; 2keto-3dGluconate_permease.
DR   Pfam; PF03812; KdgT; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Sugar transport; Symport;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..320
FT                   /note="2-keto-3-deoxygluconate permease"
FT                   /id="PRO_1000031953"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT   TRANSMEM        42..62
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT   TRANSMEM        143..163
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT   TRANSMEM        165..185
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT   TRANSMEM        199..219
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT   TRANSMEM        253..273
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT   TRANSMEM        288..308
FT                   /note="Helical"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
SQ   SEQUENCE   320 AA;  32830 MW;  7DD10E2D2F1A372A CRC64;
     MKIKATLERV PGGMMVIPLF LGTLINTLFP NAANTFGSFT GALLTGALPI LAVFFVCMGA
     TIDFKATPYI LKKGGALWIT KILIGVIVGV IGAKFLGEGM IKSGPFVGLS VLALVASMND
     TNGGLYMALM GQFGKKEDVA AYSVMSLESG PFFTMVTLGV AGLSAFPWQM LVGAILPLII
     GMILGNLDKE LREFFGRAVP VLIPFFAFGL GAKMNLLDVW KAGLVGILVG VAVVVITGTA
     LFIADRLTGG NGIAGLAAAS TAGNAAAVPA VVASANHAYA PVAPAATAIV ASSVIVTAFL
     VPIITAWWAK RIGVVNNNAA