KDGT_DICCH
ID KDGT_DICCH Reviewed; 339 AA.
AC P15701;
DT 01-APR-1990, integrated into UniProtKB/Swiss-Prot.
DT 30-MAY-2000, sequence version 2.
DT 25-MAY-2022, entry version 90.
DE RecName: Full=2-keto-3-deoxygluconate permease;
DE Short=KDG permease;
GN Name=kdgT;
OS Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Pectobacteriaceae; Dickeya.
OX NCBI_TaxID=556;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=2684787; DOI=10.1016/0378-1119(89)90109-1;
RA Allen C., Reverchon S., Robert-Baudouy J.;
RT "Nucleotide sequence of the Erwinia chrysanthemi gene encoding 2-keto-3-
RT deoxygluconate permease.";
RL Gene 83:233-241(1989).
CC -!- FUNCTION: The 2-keto-3-deoxygluconate permease transports the degraded
CC pectin products into the bacterial cell, where they serve as carbon and
CC energy sources. This is a hydrogen coupled transport system.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000250}; Multi-pass
CC membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the KdgT transporter family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAA83925.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; M31456; AAA83925.1; ALT_INIT; Genomic_DNA.
DR PIR; JQ0113; JQ0113.
DR AlphaFoldDB; P15701; -.
DR TCDB; 2.A.10.1.1; the 2-keto-3-deoxygluconate transporter (kdgt) family.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015649; F:2-keto-3-deoxygluconate:proton symporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00070; KdgT; 1.
DR InterPro; IPR004684; 2keto-3dGluconate_permease.
DR InterPro; IPR018395; 2keto-3dGluconate_permease_sub.
DR Pfam; PF03812; KdgT; 1.
DR TIGRFAMs; TIGR00793; kdgT; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Sugar transport; Symport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..339
FT /note="2-keto-3-deoxygluconate permease"
FT /id="PRO_0000209679"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 77..97
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 100..120
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 141..161
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 163..183
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 254..274
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000255"
FT REGION 315..339
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 316..339
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 339 AA; 35037 MW; 9AD38FFDDF67F475 CRC64;
MHIKRSIEKI PGGMMLVPLF LGALCHTFAP GAGKYFGSFT NGLISGTVPI LAVWFFCMGA
SIRLSATGTV LRKSGTLVVT KIAVAWVVAA VASRILPENG VEVGFFAGLS TLALVAAMDM
TNGGLYASIM QQYGTKEESG AFVLMSLESG PLMTMVILGT AGIASFEPHV FVGAVLPFLV
GFALGNLDPE LRDFFSRAVQ TLIPFFAFAL GNTIDLSVIG QTGLLGVLLG ISVIIITGIP
LIVADKVLGG GDGTAGIAAS SSAGAAVATP VLIAEMVPAF KPVAPAATTL VATSVIVTSV
LVPIITAMWS KRVKGGDGTV PKEDAVEEKA EQQRRRIIK