KDGT_ECODH
ID KDGT_ECODH Reviewed; 327 AA.
AC B1XB76;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 20-MAY-2008, sequence version 1.
DT 03-AUG-2022, entry version 70.
DE RecName: Full=2-keto-3-deoxygluconate permease {ECO:0000255|HAMAP-Rule:MF_00070};
DE Short=KDG permease {ECO:0000255|HAMAP-Rule:MF_00070};
GN Name=kdgT {ECO:0000255|HAMAP-Rule:MF_00070};
GN OrderedLocusNames=ECDH10B_4099;
OS Escherichia coli (strain K12 / DH10B).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Escherichia.
OX NCBI_TaxID=316385;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=K12 / DH10B;
RX PubMed=18245285; DOI=10.1128/jb.01695-07;
RA Durfee T., Nelson R., Baldwin S., Plunkett G. III, Burland V., Mau B.,
RA Petrosino J.F., Qin X., Muzny D.M., Ayele M., Gibbs R.A., Csorgo B.,
RA Posfai G., Weinstock G.M., Blattner F.R.;
RT "The complete genome sequence of Escherichia coli DH10B: insights into the
RT biology of a laboratory workhorse.";
RL J. Bacteriol. 190:2597-2606(2008).
CC -!- FUNCTION: The 2-keto-3-deoxygluconate permease transports the degraded
CC pectin products into the bacterial cell, where they serve as carbon and
CC energy sources. This is a hydrogen coupled transport system.
CC {ECO:0000255|HAMAP-Rule:MF_00070}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00070}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_00070}.
CC -!- SIMILARITY: Belongs to the KdgT transporter family. {ECO:0000255|HAMAP-
CC Rule:MF_00070}.
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DR EMBL; CP000948; ACB04922.1; -; Genomic_DNA.
DR RefSeq; WP_001166063.1; NC_010473.1.
DR AlphaFoldDB; B1XB76; -.
DR GeneID; 66672182; -.
DR KEGG; ecd:ECDH10B_4099; -.
DR HOGENOM; CLU_057476_0_1_6; -.
DR OMA; ESGPFMT; -.
DR BioCyc; ECOL316385:ECDH10B_RS20875-MON; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015649; F:2-keto-3-deoxygluconate:proton symporter activity; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00070; KdgT; 1.
DR InterPro; IPR004684; 2keto-3dGluconate_permease.
DR InterPro; IPR018395; 2keto-3dGluconate_permease_sub.
DR Pfam; PF03812; KdgT; 1.
DR TIGRFAMs; TIGR00793; kdgT; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Membrane; Sugar transport; Symport;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..327
FT /note="2-keto-3-deoxygluconate permease"
FT /id="PRO_1000092362"
FT TRANSMEM 10..30
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT TRANSMEM 42..62
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT TRANSMEM 73..93
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT TRANSMEM 95..115
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT TRANSMEM 139..159
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT TRANSMEM 163..183
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT TRANSMEM 199..219
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT TRANSMEM 224..244
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT TRANSMEM 254..274
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
FT TRANSMEM 289..309
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00070"
SQ SEQUENCE 327 AA; 33669 MW; 8F870CB233B35453 CRC64;
MQIKRSIEKI PGGMMLVPLF LGALCHTFSP GAGKYFGSFT NGMITGTVPI LAVWFFCMGA
SIKLSATGTV LRKSGTLVVT KIAVAWVVAA IASRIIPEHG VEVGFFAGLS TLALVAAMDM
TNGGLYASIM QQYGTKEEAG AFVLMSLESG PLMTMIILGT AGIASFEPHV FVGAVLPFLV
GFALGNLDPE LREFFSKAVQ TLIPFFAFAL GNTIDLTVIA QTGLLGILLG VAVIIVTGIP
LIIADKLIGG GDGTAGIAAS SSAGAAVATP VLIAEMVPAF KPMAPAATSL VATAVIVTSI
LVPILTSIWS RKVKARAAKI EILGTVK
