KDPA_CAUVC
ID KDPA_CAUVC Reviewed; 570 AA.
AC Q9A7X8;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 102.
DE RecName: Full=Potassium-transporting ATPase potassium-binding subunit {ECO:0000255|HAMAP-Rule:MF_00275};
DE AltName: Full=ATP phosphohydrolase [potassium-transporting] A chain {ECO:0000255|HAMAP-Rule:MF_00275};
DE AltName: Full=Potassium-binding and translocating subunit A {ECO:0000255|HAMAP-Rule:MF_00275};
DE AltName: Full=Potassium-translocating ATPase A chain {ECO:0000255|HAMAP-Rule:MF_00275};
GN Name=kdpA {ECO:0000255|HAMAP-Rule:MF_00275}; OrderedLocusNames=CC_1591;
OS Caulobacter vibrioides (strain ATCC 19089 / CB15) (Caulobacter crescentus).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Caulobacterales;
OC Caulobacteraceae; Caulobacter.
OX NCBI_TaxID=190650;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 19089 / CB15;
RX PubMed=11259647; DOI=10.1073/pnas.061029298;
RA Nierman W.C., Feldblyum T.V., Laub M.T., Paulsen I.T., Nelson K.E.,
RA Eisen J.A., Heidelberg J.F., Alley M.R.K., Ohta N., Maddock J.R.,
RA Potocka I., Nelson W.C., Newton A., Stephens C., Phadke N.D., Ely B.,
RA DeBoy R.T., Dodson R.J., Durkin A.S., Gwinn M.L., Haft D.H., Kolonay J.F.,
RA Smit J., Craven M.B., Khouri H.M., Shetty J., Berry K.J., Utterback T.R.,
RA Tran K., Wolf A.M., Vamathevan J.J., Ermolaeva M.D., White O.,
RA Salzberg S.L., Venter J.C., Shapiro L., Fraser C.M.;
RT "Complete genome sequence of Caulobacter crescentus.";
RL Proc. Natl. Acad. Sci. U.S.A. 98:4136-4141(2001).
CC -!- FUNCTION: Part of the high-affinity ATP-driven potassium transport (or
CC Kdp) system, which catalyzes the hydrolysis of ATP coupled with the
CC electrogenic transport of potassium into the cytoplasm. This subunit
CC binds the periplasmic potassium ions and delivers the ions to the
CC membrane domain of KdpB through an intramembrane tunnel.
CC {ECO:0000255|HAMAP-Rule:MF_00275}.
CC -!- SUBUNIT: The system is composed of three essential subunits: KdpA, KdpB
CC and KdpC. {ECO:0000255|HAMAP-Rule:MF_00275}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00275}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_00275}.
CC -!- SIMILARITY: Belongs to the KdpA family. {ECO:0000255|HAMAP-
CC Rule:MF_00275}.
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DR EMBL; AE005673; AAK23570.1; -; Genomic_DNA.
DR PIR; F87446; F87446.
DR RefSeq; NP_420402.1; NC_002696.2.
DR RefSeq; WP_010919465.1; NC_002696.2.
DR AlphaFoldDB; Q9A7X8; -.
DR SMR; Q9A7X8; -.
DR STRING; 190650.CC_1591; -.
DR EnsemblBacteria; AAK23570; AAK23570; CC_1591.
DR KEGG; ccr:CC_1591; -.
DR PATRIC; fig|190650.5.peg.1618; -.
DR eggNOG; COG2060; Bacteria.
DR HOGENOM; CLU_018614_3_0_5; -.
DR OMA; RQGWAIL; -.
DR BioCyc; CAULO:CC1591-MON; -.
DR Proteomes; UP000001816; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0008556; F:P-type potassium transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0030955; F:potassium ion binding; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00275; KdpA; 1.
DR InterPro; IPR004623; KdpA.
DR PANTHER; PTHR30607; PTHR30607; 1.
DR Pfam; PF03814; KdpA; 1.
DR PIRSF; PIRSF001294; K_ATPaseA; 1.
DR TIGRFAMs; TIGR00680; kdpA; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW Potassium transport; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..570
FT /note="Potassium-transporting ATPase potassium-binding
FT subunit"
FT /id="PRO_0000166489"
FT TRANSMEM 7..27
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 65..85
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 95..115
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 179..199
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 254..274
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 286..306
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 383..403
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 422..442
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 489..509
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 528..548
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
SQ SEQUENCE 570 AA; 59271 MW; 026923230CA67AC5 CRC64;
MTWQGWAEIA LTLSLAVAIG WPLGVFLSRV WNGEKTFLDP VMRPVEGLFY KACGVDPSKS
QSWHAYALAL LAFNLIGFVF VYAVLRLQGV LPLNPQGFPG LSGHLAFNTA ISFITNTNWQ
SYAGETTMST LSQMLVLTVQ NFVSAATGAT VAAALARAFV ANRGEGVGNF WADLVRTTLY
LLLPLAFVVA VVLAALGLPQ TLAAGVTAHT LEGAEQKISL YAVASQEAIK MLGINGGGIF
NANSAHPFEN PTPLTNLITA ISINTLGWAA FFAFGRTVLA KKDVRALVIA AFVLLFAGAV
GVYATETQAP PAQVAAQVDT SANMEGKEVR FGAPATAAWV AMTTGASNGS VNGKHSSLMP
LGGGIAMFLM QLGEILPGGI GSGVAIMVVM ALLSVFVAGL MVGRTPEYLG KKVEAREIQF
SILAVVIIPL SMLGFSGIAA VLPEALKGLM HSGPHGLSEI LYAYVSGTAN NGSAFAGLTA
NAPWWNVTLG IAMAMGRFMP IVAVLAIAGS LVTKPKLAPT AGTLPTDGGL FIGLLIGVIL
ILGGLQFFPA MALGPIVEHF QALDAVAALR
