KDPA_GLOVI
ID KDPA_GLOVI Reviewed; 575 AA.
AC Q7NN41;
DT 15-MAR-2005, integrated into UniProtKB/Swiss-Prot.
DT 15-DEC-2003, sequence version 1.
DT 03-AUG-2022, entry version 106.
DE RecName: Full=Potassium-transporting ATPase potassium-binding subunit {ECO:0000255|HAMAP-Rule:MF_00275};
DE AltName: Full=ATP phosphohydrolase [potassium-transporting] A chain {ECO:0000255|HAMAP-Rule:MF_00275};
DE AltName: Full=Potassium-binding and translocating subunit A {ECO:0000255|HAMAP-Rule:MF_00275};
DE AltName: Full=Potassium-translocating ATPase A chain {ECO:0000255|HAMAP-Rule:MF_00275};
GN Name=kdpA {ECO:0000255|HAMAP-Rule:MF_00275}; OrderedLocusNames=glr0573;
OS Gloeobacter violaceus (strain ATCC 29082 / PCC 7421).
OC Bacteria; Cyanobacteria; Gloeobacteria; Gloeobacterales; Gloeobacteraceae;
OC Gloeobacter.
OX NCBI_TaxID=251221;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 29082 / PCC 7421;
RX PubMed=14621292; DOI=10.1093/dnares/10.4.137;
RA Nakamura Y., Kaneko T., Sato S., Mimuro M., Miyashita H., Tsuchiya T.,
RA Sasamoto S., Watanabe A., Kawashima K., Kishida Y., Kiyokawa C., Kohara M.,
RA Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Takeuchi C., Yamada M.,
RA Tabata S.;
RT "Complete genome structure of Gloeobacter violaceus PCC 7421, a
RT cyanobacterium that lacks thylakoids.";
RL DNA Res. 10:137-145(2003).
CC -!- FUNCTION: Part of the high-affinity ATP-driven potassium transport (or
CC Kdp) system, which catalyzes the hydrolysis of ATP coupled with the
CC electrogenic transport of potassium into the cytoplasm. This subunit
CC binds the periplasmic potassium ions and delivers the ions to the
CC membrane domain of KdpB through an intramembrane tunnel.
CC {ECO:0000255|HAMAP-Rule:MF_00275}.
CC -!- SUBUNIT: The system is composed of three essential subunits: KdpA, KdpB
CC and KdpC. {ECO:0000255|HAMAP-Rule:MF_00275}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00275}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_00275}.
CC -!- SIMILARITY: Belongs to the KdpA family. {ECO:0000255|HAMAP-
CC Rule:MF_00275}.
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DR EMBL; BA000045; BAC88514.1; -; Genomic_DNA.
DR RefSeq; NP_923519.1; NC_005125.1.
DR RefSeq; WP_011140576.1; NC_005125.1.
DR AlphaFoldDB; Q7NN41; -.
DR SMR; Q7NN41; -.
DR STRING; 251221.35211135; -.
DR EnsemblBacteria; BAC88514; BAC88514; BAC88514.
DR KEGG; gvi:glr0573; -.
DR PATRIC; fig|251221.4.peg.581; -.
DR eggNOG; COG2060; Bacteria.
DR HOGENOM; CLU_018614_3_0_3; -.
DR InParanoid; Q7NN41; -.
DR OMA; RQGWAIL; -.
DR OrthoDB; 296671at2; -.
DR PhylomeDB; Q7NN41; -.
DR Proteomes; UP000000557; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0008556; F:P-type potassium transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0030955; F:potassium ion binding; IEA:UniProtKB-UniRule.
DR GO; GO:0071805; P:potassium ion transmembrane transport; IBA:GO_Central.
DR HAMAP; MF_00275; KdpA; 1.
DR InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR InterPro; IPR004623; KdpA.
DR PANTHER; PTHR30607; PTHR30607; 1.
DR Pfam; PF03814; KdpA; 1.
DR PIRSF; PIRSF001294; K_ATPaseA; 1.
DR SUPFAM; SSF81665; SSF81665; 1.
DR TIGRFAMs; TIGR00680; kdpA; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW Potassium transport; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..575
FT /note="Potassium-transporting ATPase potassium-binding
FT subunit"
FT /id="PRO_0000166500"
FT TRANSMEM 3..23
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 69..89
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 136..156
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 178..198
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 266..286
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 293..313
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 340..360
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 367..387
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 391..411
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 431..451
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 498..518
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 543..563
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
SQ SEQUENCE 575 AA; 61127 MW; 6F44AC356B51B5F4 CRC64;
MAFEGVLQIV ATLVLMVAIV PFFGTYMARV FQGESTWLDR VLGPIENLVY RLGGVRPELT
MDWWSYARAV LASNAAMFVP VFAVLLLQGS LPLNPNGISG MSWDLALHTA ISFLTNTNQQ
HYSGETGASH LAQMVCFQFL MFTSAATGLA VGIAFIRGLL GKPLGNFYVD LTRSVSRILM
PISIAFAVVL LSQGVPQSLG GTTEAQLVDP YRTEQDGKRE QVTAQKLVSG PFASMESIKE
LGENGGGSYG INSAHPYENP NPFTNLLEIL LLLAVPTSLI YTFGVLANNK KQGWVLFGTI
FVLFVGLVGV AALGEYWGNP TVNALLGSAN PNFEGQEVRF GWAQSALFAT ATTGTMTGAV
NAMHDSLTPL AGLVTLFNLC LQVIWGGQGT GIAYILVFLI IAVFLTGLMV GRTPEIFGRK
LEKREVALAS IIFLVHPVII LVPTAIALAI PGLAGNSNPG FHGLTQVVYE YASAAANNGS
GFEGLGDATP WWNLSTSVVL LLGRYAPIVA LLALAGGLQR KQPVPETPGT LRTDTVLFGS
VTAGTILILG ALTFFPVFAL GPIAEWIANL AGKTL
