KDPA_MICAN
ID KDPA_MICAN Reviewed; 581 AA.
AC B0JJ94;
DT 24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT 18-MAR-2008, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Potassium-transporting ATPase potassium-binding subunit {ECO:0000255|HAMAP-Rule:MF_00275};
DE AltName: Full=ATP phosphohydrolase [potassium-transporting] A chain {ECO:0000255|HAMAP-Rule:MF_00275};
DE AltName: Full=Potassium-binding and translocating subunit A {ECO:0000255|HAMAP-Rule:MF_00275};
DE AltName: Full=Potassium-translocating ATPase A chain {ECO:0000255|HAMAP-Rule:MF_00275};
GN Name=kdpA {ECO:0000255|HAMAP-Rule:MF_00275}; OrderedLocusNames=MAE_59800;
OS Microcystis aeruginosa (strain NIES-843 / IAM M-2473).
OC Bacteria; Cyanobacteria; Oscillatoriophycideae; Chroococcales;
OC Microcystaceae; Microcystis.
OX NCBI_TaxID=449447;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NIES-843 / IAM M-247;
RX PubMed=18192279; DOI=10.1093/dnares/dsm026;
RA Kaneko T., Nakajima N., Okamoto S., Suzuki I., Tanabe Y., Tamaoki M.,
RA Nakamura Y., Kasai F., Watanabe A., Kawashima K., Kishida Y., Ono A.,
RA Shimizu Y., Takahashi C., Minami C., Fujishiro T., Kohara M., Katoh M.,
RA Nakazaki N., Nakayama S., Yamada M., Tabata S., Watanabe M.M.;
RT "Complete genomic structure of the bloom-forming toxic cyanobacterium
RT Microcystis aeruginosa NIES-843.";
RL DNA Res. 14:247-256(2007).
CC -!- FUNCTION: Part of the high-affinity ATP-driven potassium transport (or
CC Kdp) system, which catalyzes the hydrolysis of ATP coupled with the
CC electrogenic transport of potassium into the cytoplasm. This subunit
CC binds the periplasmic potassium ions and delivers the ions to the
CC membrane domain of KdpB through an intramembrane tunnel.
CC {ECO:0000255|HAMAP-Rule:MF_00275}.
CC -!- SUBUNIT: The system is composed of three essential subunits: KdpA, KdpB
CC and KdpC. {ECO:0000255|HAMAP-Rule:MF_00275}.
CC -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_00275}; Multi-pass membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_00275}.
CC -!- SIMILARITY: Belongs to the KdpA family. {ECO:0000255|HAMAP-
CC Rule:MF_00275}.
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DR EMBL; AP009552; BAG05802.1; -; Genomic_DNA.
DR RefSeq; WP_012268152.1; NC_010296.1.
DR AlphaFoldDB; B0JJ94; -.
DR SMR; B0JJ94; -.
DR STRING; 449447.MAE_59800; -.
DR PaxDb; B0JJ94; -.
DR EnsemblBacteria; BAG05802; BAG05802; MAE_59800.
DR KEGG; mar:MAE_59800; -.
DR PATRIC; fig|449447.4.peg.5479; -.
DR eggNOG; COG2060; Bacteria.
DR HOGENOM; CLU_018614_3_0_3; -.
DR OMA; RQGWAIL; -.
DR OrthoDB; 296671at2; -.
DR BioCyc; MAER449447:MAE_RS26090-MON; -.
DR Proteomes; UP000001510; Chromosome.
DR GO; GO:0005887; C:integral component of plasma membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0008556; F:P-type potassium transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0030955; F:potassium ion binding; IEA:UniProtKB-UniRule.
DR HAMAP; MF_00275; KdpA; 1.
DR InterPro; IPR004623; KdpA.
DR PANTHER; PTHR30607; PTHR30607; 1.
DR Pfam; PF03814; KdpA; 1.
DR PIRSF; PIRSF001294; K_ATPaseA; 1.
DR TIGRFAMs; TIGR00680; kdpA; 1.
PE 3: Inferred from homology;
KW Cell inner membrane; Cell membrane; Ion transport; Membrane; Potassium;
KW Potassium transport; Reference proteome; Transmembrane;
KW Transmembrane helix; Transport.
FT CHAIN 1..581
FT /note="Potassium-transporting ATPase potassium-binding
FT subunit"
FT /id="PRO_1000114693"
FT TRANSMEM 2..22
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 74..94
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 135..155
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 177..197
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 255..275
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 284..304
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 332..352
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 357..377
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 381..401
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 421..441
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 501..521
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
FT TRANSMEM 550..570
FT /note="Helical"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00275"
SQ SEQUENCE 581 AA; 61895 MW; 757FAA177C0E51D0 CRC64;
MLQGWIQIAL TILIIVAITP FFGRYMARVF MERRTLLDPL CDRVESLLYT FVGVKGKENM
TGWQYTRAVL YSNAVIAILV FSLIAGQGVL PLNPTGIPAP SWDTTLHTTI SFITNSDQQH
YSGETTLSYG SQIWGLGYQM FTSAGTGLAV GIAFIRGLTG RPLGNFYVDL IRAITRILLP
ISIVGAIALI IAGVPETLAG PAILPTLENP NLSQAIARGP VAHFEIIKEL GENGGGFFAS
NSAHPFENPN GFVNLVQLVA ILSIPTSLIY TYGVFADNLK QARLIYLIPL GIFIGFTIIT
AIGEYNGNQA VNSLLGVERA VNFEGKEVRF GWAQSALYAV TTTATMCGAV IAMHDSLMPN
GGFATLSNLF LQIVFGGQGT GTAYLFAYLI LAVFVTGLMV GRTPEFLGRK IEKREVVLAS
FLILLVHPIA ILIPGAIALA FPDFQGISNP GFHGLSQVIY EYASAAANNG SGFEGLGDSQ
PAPLAIAAGA KPTITALWWN LSACFSLLAG RYIPIAALLL LADGMSRKQP VPATTGTLRT
DTGLFTSVTA GVILILGALT FLPILALGPI AEAFQITRMI G
