AR26L_HUMAN
ID AR26L_HUMAN Reviewed; 321 AA.
AC Q6NSI1;
DT 18-MAR-2008, integrated into UniProtKB/Swiss-Prot.
DT 05-OCT-2010, sequence version 2.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=Putative ankyrin repeat domain-containing protein 26-like protein;
GN Name=ANKRD26P1;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15616553; DOI=10.1038/nature03187;
RA Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G.,
RA Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E.,
RA Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J., Buckingham J.M.,
RA Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C.,
RA Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M.,
RA Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M.,
RA Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D.,
RA Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L.,
RA Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E.,
RA Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H.,
RA Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y.,
RA Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J.,
RA Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D.,
RA Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S.,
RA Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A.,
RA Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M.,
RA Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H.,
RA Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A.,
RA Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J.,
RA DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J.,
RA Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M.,
RA Myers R.M., Rubin E.M., Pennacchio L.A.;
RT "The sequence and analysis of duplication-rich human chromosome 16.";
RL Nature 432:988-994(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT THR-265.
RC TISSUE=Testis;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q6NSI1; P43360: MAGEA6; NbExp=3; IntAct=EBI-10250923, EBI-1045155;
CC -!- CAUTION: Could be the product of a pseudogene. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AC092368; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC106819; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; BC070117; -; NOT_ANNOTATED_CDS; mRNA.
DR AlphaFoldDB; Q6NSI1; -.
DR SMR; Q6NSI1; -.
DR IntAct; Q6NSI1; 2.
DR MINT; Q6NSI1; -.
DR BioMuta; HGNC:32955; -.
DR DMDM; 306526200; -.
DR MassIVE; Q6NSI1; -.
DR PeptideAtlas; Q6NSI1; -.
DR PRIDE; Q6NSI1; -.
DR ProteomicsDB; 66628; -.
DR GeneCards; ANKRD26P1; -.
DR HGNC; HGNC:32955; ANKRD26P1.
DR neXtProt; NX_Q6NSI1; -.
DR InParanoid; Q6NSI1; -.
DR PhylomeDB; Q6NSI1; -.
DR PathwayCommons; Q6NSI1; -.
DR SignaLink; Q6NSI1; -.
DR ChiTaRS; ANKRD26P1; human.
DR Pharos; Q6NSI1; Tdark.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; Q6NSI1; protein.
DR Gene3D; 1.25.40.20; -; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR Pfam; PF12796; Ank_2; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 4.
DR SUPFAM; SSF48403; SSF48403; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 1.
DR PROSITE; PS50088; ANK_REPEAT; 3.
PE 5: Uncertain;
KW ANK repeat; Reference proteome; Repeat.
FT CHAIN 1..321
FT /note="Putative ankyrin repeat domain-containing protein
FT 26-like protein"
FT /id="PRO_0000326201"
FT REPEAT 48..78
FT /note="ANK 1"
FT REPEAT 82..111
FT /note="ANK 2"
FT REPEAT 115..144
FT /note="ANK 3"
FT REPEAT 148..177
FT /note="ANK 4"
FT REPEAT 181..210
FT /note="ANK 5"
FT REGION 222..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 268..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 225..242
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 277..297
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VARIANT 265
FT /note="K -> T (in dbSNP:rs1436436)"
FT /evidence="ECO:0000269|PubMed:15489334"
FT /id="VAR_040003"
SQ SEQUENCE 321 AA; 35437 MW; 7FDB6EE37D716EB4 CRC64;
MRRSSGFGGQ KGQGPSCSFT GCWCCRGDDV AESDDSPFAQ CGYNIQEKHL GKLHRAASRG
EVSKVECILS SGSADLDERD KKKRTALHLA CANGHPEVVA LLVDRGCQLD VFDNKNRTAL
LKAVQCQEEE CATILLEHGA DPDLPDVYGN TTLHYAIYNE DIPMTKKLLL HHANIESANK
DELTPFLLAV HEQKQQMEDF LRKQKENLTA VKLESIHQVM SEYKENETPR NPQNSNPEGT
SNKMACLGEG AAGAKVDEIP GNPVKRLFNK PSIDDSRPMS ANEDFDFDTE EKATEPANGK
RQNGMGIIES APQEHTNNEN I
