AR2BP_CHICK
ID AR2BP_CHICK Reviewed; 156 AA.
AC Q5ZKW5;
DT 15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT 23-NOV-2004, sequence version 1.
DT 03-AUG-2022, entry version 96.
DE RecName: Full=ADP-ribosylation factor-like protein 2-binding protein;
DE Short=ARF-like 2-binding protein;
GN Name=ARL2BP; ORFNames=RCJMB04_8o4;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=CB; TISSUE=Bursa of Fabricius;
RX PubMed=15642098; DOI=10.1186/gb-2004-6-1-r6;
RA Caldwell R.B., Kierzek A.M., Arakawa H., Bezzubov Y., Zaim J., Fiedler P.,
RA Kutter S., Blagodatski A., Kostovska D., Koter M., Plachy J., Carninci P.,
RA Hayashizaki Y., Buerstedde J.-M.;
RT "Full-length cDNAs from chicken bursal lymphocytes to facilitate gene
RT function analysis.";
RL Genome Biol. 6:R6.1-R6.9(2005).
CC -!- FUNCTION: Plays a role as an effector of the ADP-ribosylation factor-
CC like protein 2, ARL2. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Mitochondrion
CC intermembrane space {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule
CC organizing center, centrosome {ECO:0000250}. Nucleus {ECO:0000250}.
CC Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Cytoplasm,
CC cytoskeleton, cilium basal body {ECO:0000250}. Note=Detected in the
CC midbody matrix. Not detected in the Golgi, nucleus and on the mitotic
CC spindle. Centrosome-associated throughout the cell cycle. Not detected
CC to interphase microtubules. The complex formed with ARL2BP, ARL2 and
CC SLC25A4 is expressed in mitochondria (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ARL2BP family. {ECO:0000305}.
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DR EMBL; AJ719969; CAG31628.1; -; mRNA.
DR RefSeq; NP_001007971.1; NM_001007970.1.
DR RefSeq; XP_015147835.1; XM_015292349.1.
DR RefSeq; XP_015157294.1; XM_015301808.1.
DR AlphaFoldDB; Q5ZKW5; -.
DR SMR; Q5ZKW5; -.
DR STRING; 9031.ENSGALP00000042358; -.
DR PaxDb; Q5ZKW5; -.
DR Ensembl; ENSGALT00000102793; ENSGALP00000067034; ENSGALG00000049492.
DR GeneID; 426495; -.
DR KEGG; gga:426495; -.
DR CTD; 23568; -.
DR VEuPathDB; HostDB:geneid_426495; -.
DR eggNOG; ENOG502RYJD; Eukaryota.
DR GeneTree; ENSGT00390000015052; -.
DR HOGENOM; CLU_116781_0_0_1; -.
DR InParanoid; Q5ZKW5; -.
DR OMA; LIQRNFM; -.
DR OrthoDB; 1403493at2759; -.
DR PhylomeDB; Q5ZKW5; -.
DR PRO; PR:Q5ZKW5; -.
DR Proteomes; UP000000539; Chromosome 11.
DR Bgee; ENSGALG00000049492; Expressed in spermatid and 13 other tissues.
DR ExpressionAtlas; Q5ZKW5; baseline and differential.
DR GO; GO:0005929; C:cilium; IEA:UniProtKB-KW.
DR GO; GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
DR GO; GO:0005758; C:mitochondrial intermembrane space; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR GO; GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.
DR GO; GO:0051457; P:maintenance of protein location in nucleus; ISS:UniProtKB.
DR GO; GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.
DR Gene3D; 1.20.1520.10; -; 1.
DR InterPro; IPR038849; ARL2BP.
DR InterPro; IPR023379; BART_dom.
DR InterPro; IPR042541; BART_sf.
DR PANTHER; PTHR15487; PTHR15487; 1.
DR Pfam; PF11527; ARL2_Bind_BART; 1.
PE 2: Evidence at transcript level;
KW Cell projection; Cilium; Cytoplasm; Cytoskeleton; Mitochondrion; Nucleus;
KW Reference proteome.
FT CHAIN 1..156
FT /note="ADP-ribosylation factor-like protein 2-binding
FT protein"
FT /id="PRO_0000287118"
SQ SEQUENCE 156 AA; 17936 MW; F54E9DD2A730B246 CRC64;
METSEEENFG VAVSSPSDAE FDAVVGYLED IIMDDDFQSI QRTFMEKHYQ EFDDSEENKL
IYTSIFNEYI SLIEKYIEEK LLDRIPGFNM TAFTMSLQQH KDEMAGDIFD MLLTFTDFLA
FKEMFLDYRA EKEGRSLDLS GGLVVTSLNK SSVSSS