ID   AR2BP_XENTR             Reviewed;         157 AA.
AC   Q5FW25;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=ADP-ribosylation factor-like protein 2-binding protein;
DE            Short=ARF-like 2-binding protein;
GN   Name=arl2bp; ORFNames=TEgg016g21.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=N6; TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role as an effector of the ADP-ribosylation factor-
CC       like protein 2, ARL2. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Mitochondrion
CC       intermembrane space {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule
CC       organizing center, centrosome {ECO:0000250}. Nucleus {ECO:0000250}.
CC       Cytoplasm, cytoskeleton, spindle {ECO:0000250}. Cytoplasm,
CC       cytoskeleton, cilium basal body {ECO:0000250}. Note=Detected in the
CC       midbody matrix. Not detected in the Golgi, nucleus and on the mitotic
CC       spindle. Centrosome-associated throughout the cell cycle. Not detected
CC       to interphase microtubules. The complex formed with ARL2BP, ARL2 and
CC       SLC25A4 is expressed in mitochondria (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the ARL2BP family. {ECO:0000305}.
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DR   EMBL; CR762122; CAJ81899.1; -; mRNA.
DR   EMBL; BC089656; AAH89656.1; -; mRNA.
DR   EMBL; BC121547; AAI21548.1; -; mRNA.
DR   RefSeq; NP_001017020.1; NM_001017020.2.
DR   RefSeq; XP_012816619.1; XM_012961165.2.
DR   RefSeq; XP_012816620.1; XM_012961166.2.
DR   AlphaFoldDB; Q5FW25; -.
DR   SMR; Q5FW25; -.
DR   PaxDb; Q5FW25; -.
DR   Ensembl; ENSXETT00000039869; ENSXETP00000039869; ENSXETG00000018410.
DR   GeneID; 549774; -.
DR   KEGG; xtr:549774; -.
DR   CTD; 23568; -.
DR   Xenbase; XB-GENE-943387; arl2bp.
DR   eggNOG; ENOG502RYJD; Eukaryota.
DR   HOGENOM; CLU_116781_0_0_1; -.
DR   InParanoid; Q5FW25; -.
DR   OMA; CILEIIM; -.
DR   OrthoDB; 1403493at2759; -.
DR   PhylomeDB; Q5FW25; -.
DR   TreeFam; TF315143; -.
DR   Reactome; R-XTR-83936; Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane.
DR   Proteomes; UP000008143; Chromosome 4.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000018410; Expressed in egg cell and 23 other tissues.
DR   GO; GO:0005929; C:cilium; IEA:UniProtKB-KW.
DR   GO; GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.
DR   GO; GO:0005758; C:mitochondrial intermembrane space; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
DR   GO; GO:0051457; P:maintenance of protein location in nucleus; IBA:GO_Central.
DR   GO; GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; IBA:GO_Central.
DR   Gene3D; 1.20.1520.10; -; 1.
DR   InterPro; IPR038849; ARL2BP.
DR   InterPro; IPR023379; BART_dom.
DR   InterPro; IPR042541; BART_sf.
DR   PANTHER; PTHR15487; PTHR15487; 1.
DR   Pfam; PF11527; ARL2_Bind_BART; 1.
PE   2: Evidence at transcript level;
KW   Cell projection; Cilium; Cytoplasm; Cytoskeleton; Mitochondrion; Nucleus;
KW   Reference proteome.
FT   CHAIN           1..157
FT                   /note="ADP-ribosylation factor-like protein 2-binding
FT                   protein"
FT                   /id="PRO_0000287121"
SQ   SEQUENCE   157 AA;  18057 MW;  9D751E90FCE8D742 CRC64;
     MEDLEEENFT LSVSSPKDAE FDSVVGHMED IIMDDEFQLL QHGFMDKYYH EFEDTEENKL
     TYTTIFNEYI GLVEKFIEEQ LLLRIPAFNM SAFISSLQCH REEIAGDIFD ILLTFTDFLA
     FKEMFLDYKA EKEGRTVDLS CGLVVTPLIG SSVSSSS