AR6P1_DROME
ID AR6P1_DROME Reviewed; 197 AA.
AC Q9VES1;
DT 20-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=ADP-ribosylation factor-like protein 6-interacting protein 1 {ECO:0000312|FlyBase:FBgn0038453};
GN Name=Arl6IP1 {ECO:0000312|FlyBase:FBgn0038453};
GN ORFNames=CG10326 {ECO:0000312|FlyBase:FBgn0038453};
OS Drosophila melanogaster (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7227;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Berkeley;
RX PubMed=10731132; DOI=10.1126/science.287.5461.2185;
RA Adams M.D., Celniker S.E., Holt R.A., Evans C.A., Gocayne J.D.,
RA Amanatides P.G., Scherer S.E., Li P.W., Hoskins R.A., Galle R.F.,
RA George R.A., Lewis S.E., Richards S., Ashburner M., Henderson S.N.,
RA Sutton G.G., Wortman J.R., Yandell M.D., Zhang Q., Chen L.X., Brandon R.C.,
RA Rogers Y.-H.C., Blazej R.G., Champe M., Pfeiffer B.D., Wan K.H., Doyle C.,
RA Baxter E.G., Helt G., Nelson C.R., Miklos G.L.G., Abril J.F., Agbayani A.,
RA An H.-J., Andrews-Pfannkoch C., Baldwin D., Ballew R.M., Basu A.,
RA Baxendale J., Bayraktaroglu L., Beasley E.M., Beeson K.Y., Benos P.V.,
RA Berman B.P., Bhandari D., Bolshakov S., Borkova D., Botchan M.R., Bouck J.,
RA Brokstein P., Brottier P., Burtis K.C., Busam D.A., Butler H., Cadieu E.,
RA Center A., Chandra I., Cherry J.M., Cawley S., Dahlke C., Davenport L.B.,
RA Davies P., de Pablos B., Delcher A., Deng Z., Mays A.D., Dew I.,
RA Dietz S.M., Dodson K., Doup L.E., Downes M., Dugan-Rocha S., Dunkov B.C.,
RA Dunn P., Durbin K.J., Evangelista C.C., Ferraz C., Ferriera S.,
RA Fleischmann W., Fosler C., Gabrielian A.E., Garg N.S., Gelbart W.M.,
RA Glasser K., Glodek A., Gong F., Gorrell J.H., Gu Z., Guan P., Harris M.,
RA Harris N.L., Harvey D.A., Heiman T.J., Hernandez J.R., Houck J., Hostin D.,
RA Houston K.A., Howland T.J., Wei M.-H., Ibegwam C., Jalali M., Kalush F.,
RA Karpen G.H., Ke Z., Kennison J.A., Ketchum K.A., Kimmel B.E., Kodira C.D.,
RA Kraft C.L., Kravitz S., Kulp D., Lai Z., Lasko P., Lei Y., Levitsky A.A.,
RA Li J.H., Li Z., Liang Y., Lin X., Liu X., Mattei B., McIntosh T.C.,
RA McLeod M.P., McPherson D., Merkulov G., Milshina N.V., Mobarry C.,
RA Morris J., Moshrefi A., Mount S.M., Moy M., Murphy B., Murphy L.,
RA Muzny D.M., Nelson D.L., Nelson D.R., Nelson K.A., Nixon K., Nusskern D.R.,
RA Pacleb J.M., Palazzolo M., Pittman G.S., Pan S., Pollard J., Puri V.,
RA Reese M.G., Reinert K., Remington K., Saunders R.D.C., Scheeler F.,
RA Shen H., Shue B.C., Siden-Kiamos I., Simpson M., Skupski M.P., Smith T.J.,
RA Spier E., Spradling A.C., Stapleton M., Strong R., Sun E., Svirskas R.,
RA Tector C., Turner R., Venter E., Wang A.H., Wang X., Wang Z.-Y.,
RA Wassarman D.A., Weinstock G.M., Weissenbach J., Williams S.M., Woodage T.,
RA Worley K.C., Wu D., Yang S., Yao Q.A., Ye J., Yeh R.-F., Zaveri J.S.,
RA Zhan M., Zhang G., Zhao Q., Zheng L., Zheng X.H., Zhong F.N., Zhong W.,
RA Zhou X., Zhu S.C., Zhu X., Smith H.O., Gibbs R.A., Myers E.W., Rubin G.M.,
RA Venter J.C.;
RT "The genome sequence of Drosophila melanogaster.";
RL Science 287:2185-2195(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=Berkeley;
RX PubMed=12537572; DOI=10.1186/gb-2002-3-12-research0083;
RA Misra S., Crosby M.A., Mungall C.J., Matthews B.B., Campbell K.S.,
RA Hradecky P., Huang Y., Kaminker J.S., Millburn G.H., Prochnik S.E.,
RA Smith C.D., Tupy J.L., Whitfield E.J., Bayraktaroglu L., Berman B.P.,
RA Bettencourt B.R., Celniker S.E., de Grey A.D.N.J., Drysdale R.A.,
RA Harris N.L., Richter J., Russo S., Schroeder A.J., Shu S.Q., Stapleton M.,
RA Yamada C., Ashburner M., Gelbart W.M., Rubin G.M., Lewis S.E.;
RT "Annotation of the Drosophila melanogaster euchromatic genome: a systematic
RT review.";
RL Genome Biol. 3:RESEARCH0083.1-RESEARCH0083.22(2002).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Berkeley; TISSUE=Testis;
RX PubMed=12537569; DOI=10.1186/gb-2002-3-12-research0080;
RA Stapleton M., Carlson J.W., Brokstein P., Yu C., Champe M., George R.A.,
RA Guarin H., Kronmiller B., Pacleb J.M., Park S., Wan K.H., Rubin G.M.,
RA Celniker S.E.;
RT "A Drosophila full-length cDNA resource.";
RL Genome Biol. 3:RESEARCH0080.1-RESEARCH0080.8(2002).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the ARL6ip family. {ECO:0000305}.
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DR EMBL; AE014297; AAF55348.1; -; Genomic_DNA.
DR EMBL; AY094659; AAM11012.1; -; mRNA.
DR RefSeq; NP_001262647.1; NM_001275718.1.
DR RefSeq; NP_650570.1; NM_142313.3.
DR AlphaFoldDB; Q9VES1; -.
DR BioGRID; 67072; 5.
DR DIP; DIP-17988N; -.
DR STRING; 7227.FBpp0082786; -.
DR PaxDb; Q9VES1; -.
DR PRIDE; Q9VES1; -.
DR DNASU; 42027; -.
DR EnsemblMetazoa; FBtr0083336; FBpp0082786; FBgn0038453.
DR EnsemblMetazoa; FBtr0333728; FBpp0305875; FBgn0038453.
DR GeneID; 42027; -.
DR KEGG; dme:Dmel_CG10326; -.
DR UCSC; CG10326-RA; d. melanogaster.
DR CTD; 23204; -.
DR FlyBase; FBgn0038453; Arl6IP1.
DR VEuPathDB; VectorBase:FBgn0038453; -.
DR eggNOG; ENOG502QTTI; Eukaryota.
DR GeneTree; ENSGT00940000154937; -.
DR HOGENOM; CLU_100749_0_0_1; -.
DR InParanoid; Q9VES1; -.
DR OMA; VWYEYLF; -.
DR OrthoDB; 1268983at2759; -.
DR PhylomeDB; Q9VES1; -.
DR BioGRID-ORCS; 42027; 0 hits in 1 CRISPR screen.
DR GenomeRNAi; 42027; -.
DR PRO; PR:Q9VES1; -.
DR Proteomes; UP000000803; Chromosome 3R.
DR Bgee; FBgn0038453; Expressed in cleaving embryo and 38 other tissues.
DR ExpressionAtlas; Q9VES1; baseline and differential.
DR Genevisible; Q9VES1; DM.
DR GO; GO:0016021; C:integral component of membrane; IBA:GO_Central.
DR GO; GO:1990809; P:endoplasmic reticulum tubular network membrane organization; IMP:FlyBase.
PE 2: Evidence at transcript level;
KW Membrane; Reference proteome; Transmembrane; Transmembrane helix.
FT CHAIN 1..197
FT /note="ADP-ribosylation factor-like protein 6-interacting
FT protein 1"
FT /id="PRO_0000064654"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 64..84
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 129..149
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 150..170
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 197 AA; 22234 MW; 7D35ABAD18CE272E CRC64;
MAASQVDQKR ALNKLKHDLE PFRTAIVGAY GVLTWEKQYY AGVVFGVISC LYLVLWYLDL
SLITLLSLLG VISILLNYAF PMVSRLIFGG VNWDGDQEAK FEDVCGQVCA VKGSLVVWYE
YLFNERKSTV FVIVMSLGLL AMAWIGAIIN NLLLMYLATL LILMWPGLQN KDIFKAITQR
ASKIINEKIQ CGKRKLQ
