AR6P4_XENLA
ID AR6P4_XENLA Reviewed; 245 AA.
AC Q3KPW4;
DT 04-DEC-2007, integrated into UniProtKB/Swiss-Prot.
DT 04-DEC-2007, sequence version 2.
DT 03-AUG-2022, entry version 36.
DE RecName: Full=ADP-ribosylation factor-like protein 6-interacting protein 4;
DE Short=ARL-6-interacting protein 4;
DE Short=Aip-4;
GN Name=arl6ip4;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Testis;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be involved in modulating alternative pre-mRNA splicing.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}. Nucleus speckle
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the ARL6IP4 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAI06515.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; BC106514; AAI06515.1; ALT_INIT; mRNA.
DR RefSeq; XP_018118463.1; XM_018262974.1.
DR AlphaFoldDB; Q3KPW4; -.
DR PRIDE; Q3KPW4; -.
DR GeneID; 733371; -.
DR KEGG; xla:733371; -.
DR CTD; 733371; -.
DR Xenbase; XB-GENE-1188229; arl6ip4.L.
DR OMA; FQMRTGM; -.
DR OrthoDB; 1552427at2759; -.
DR Proteomes; UP000186698; Chromosome 1L.
DR Bgee; 733371; Expressed in pancreas and 19 other tissues.
DR GO; GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
DR GO; GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
DR GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR InterPro; IPR019532; Nucl_RNA-splicing_assoc_SR-25.
DR Pfam; PF10500; SR-25; 1.
PE 2: Evidence at transcript level;
KW mRNA processing; mRNA splicing; Nucleus; Reference proteome.
FT CHAIN 1..245
FT /note="ADP-ribosylation factor-like protein 6-interacting
FT protein 4"
FT /id="PRO_0000312275"
FT REGION 1..171
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..32
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 73..95
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 102..129
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 245 AA; 27721 MW; 884A1F57C24645A1 CRC64;
MMDGTHAIKR SRSRSPKVSQ SKSSKKKKRS SSRCRSGSDS PARKHSTLAK YRAEVPDRRK
KERRKKRRKR TVSTTSSSSS ESSSSSSSSS SDDSGDSTCK SKRSSHRKKK NKKQIKRKKA
KKNKKLKKKT SFKLECQDTK STEKEVLPGP SVNPCKKESP EVSGPALTDE QKSRIQAMKP
MTKEEWDAQQ SVIRKVVDPE TGRIRLIKGD GEVLEEIVSK DRHKEINKHA TQKDGLEFQM
HSGMF