ID   KEL10_CAEEL             Reviewed;         578 AA.
AC   P34569; P34570;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   07-APR-2021, sequence version 5.
DT   03-AUG-2022, entry version 132.
DE   RecName: Full=Kelch repeat-containing protein kel-10;
GN   Name=kel-10 {ECO:0000312|WormBase:T16H12.6};
GN   ORFNames=T16H12.6 {ECO:0000312|WormBase:T16H12.6};
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
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DR   EMBL; BX284603; CAA83141.4; -; Genomic_DNA.
DR   PIR; S42387; S42387.
DR   RefSeq; NP_499241.3; NM_066840.3.
DR   AlphaFoldDB; P34569; -.
DR   SMR; P34569; -.
DR   STRING; 6239.T16H12.6; -.
DR   PaxDb; P34569; -.
DR   EnsemblMetazoa; T16H12.6.1; T16H12.6.1; WBGene00002186.
DR   UCSC; T16H12.6; c. elegans.
DR   WormBase; T16H12.6; CE54163; WBGene00002186; kel-10.
DR   eggNOG; KOG4441; Eukaryota.
DR   GeneTree; ENSGT00940000154664; -.
DR   HOGENOM; CLU_468724_0_0_1; -.
DR   InParanoid; P34569; -.
DR   OrthoDB; 570251at2759; -.
DR   PhylomeDB; P34569; -.
DR   Reactome; R-CEL-8951664; Neddylation.
DR   Reactome; R-CEL-983168; Antigen processing: Ubiquitination & Proteasome degradation.
DR   PRO; PR:P34569; -.
DR   Proteomes; UP000001940; Chromosome III.
DR   Bgee; WBGene00002186; Expressed in adult organism and 1 other tissue.
DR   Gene3D; 2.120.10.80; -; 2.
DR   Gene3D; 3.30.710.10; -; 1.
DR   InterPro; IPR011705; BACK.
DR   InterPro; IPR017096; BTB-kelch_protein.
DR   InterPro; IPR000210; BTB/POZ_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR   Pfam; PF07707; BACK; 1.
DR   Pfam; PF00651; BTB; 1.
DR   Pfam; PF01344; Kelch_1; 5.
DR   PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR   SMART; SM00612; Kelch; 6.
DR   SUPFAM; SSF117281; SSF117281; 1.
DR   SUPFAM; SSF54695; SSF54695; 1.
DR   PROSITE; PS50097; BTB; 1.
PE   4: Predicted;
KW   Kelch repeat; Reference proteome; Repeat.
FT   CHAIN           1..578
FT                   /note="Kelch repeat-containing protein kel-10"
FT                   /id="PRO_0000119092"
FT   DOMAIN          51..118
FT                   /note="BTB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00037"
FT   DOMAIN          158..236
FT                   /note="BACK"
FT                   /evidence="ECO:0000255"
FT   REPEAT          265..315
FT                   /note="Kelch 1"
FT                   /evidence="ECO:0000255"
FT   REPEAT          316..362
FT                   /note="Kelch 2"
FT                   /evidence="ECO:0000255"
FT   REPEAT          368..414
FT                   /note="Kelch 3"
FT                   /evidence="ECO:0000255"
FT   REPEAT          416..462
FT                   /note="Kelch 4"
FT                   /evidence="ECO:0000255"
FT   REPEAT          464..510
FT                   /note="Kelch 5"
FT                   /evidence="ECO:0000255"
FT   REPEAT          512..558
FT                   /note="Kelch 6"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   578 AA;  65542 MW;  2628E6DB7B4F71DB CRC64;
     MDISDISASQ LATSPPPITT IDFNSSIEES PAKRVKFAPE LTKSFEETLS PTVTLVLRNN
     EETFDRCLLS FYSNYFRVLF SSKFRDSKST THRIRLISAP DLHLLLTIPK AFEQGIKPNI
     SLQKAVELLE PSAFLQMSIP LDYITDVICA NLTHENIIKI FRLALLYHTT LAVRVWRAMV
     RKFQTLFATN VYLTLKENEL IGLLTDKHLN LKSADEKTVV VNWIKHNSPL QSDRMAQFAQ
     RNFSRQPQPD ATKYEVIRTR QPMDAIVCFG GWASRGVAQN IEVFNTRSDR WQTCNFNYDI
     PNIRRAYHGI EVVEDKLIVY GGFNGTQQFQ TTVLFDLSTK EWRSGANMND KRCYVTSARI
     NDSHGRPLIF ACGGMNGVSR LKTAEMYDYR ADQWSEVANM AQMRSDGAVV TIDNKIVVIG
     GFDGRNIHQG GEVYDPVLDL WHPLSSNMRT RRTGCTAVSI MNQVCMIIGG FNGNRRLDSA
     EIYDMREGLW HPVPSLHTAR SNFSACQMDT CSIYVAGGFD GQATTKESER LDLRSKMWQA
     LPDMSEAKSA LRMVTLSDHP FLDELFDIPD DTGIITTW