ID   KEN_DROYA               Reviewed;         205 AA.
AC   P60319;
DT   02-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   02-FEB-2004, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Probable transcription factor Ken;
DE   AltName: Full=Protein Ken and Barbie;
DE   Flags: Fragment;
GN   Name=ken;
OS   Drosophila yakuba (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7245;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=14525923; DOI=10.1101/gr.1311003;
RA   Domazet-Loso T., Tautz D.;
RT   "An evolutionary analysis of orphan genes in Drosophila.";
RL   Genome Res. 13:2213-2219(2003).
CC   -!- FUNCTION: Probable transcription factor, which is required for
CC       terminalia development. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
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DR   EMBL; AY231891; AAR09914.1; -; mRNA.
DR   AlphaFoldDB; P60319; -.
DR   SMR; P60319; -.
DR   STRING; 7245.FBpp0259343; -.
DR   eggNOG; KOG1721; Eukaryota.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:EnsemblMetazoa.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0045497; P:female analia development; IEA:EnsemblMetazoa.
DR   GO; GO:0030540; P:female genitalia development; IEA:EnsemblMetazoa.
DR   GO; GO:0045496; P:male analia development; IEA:EnsemblMetazoa.
DR   GO; GO:0030539; P:male genitalia development; IEA:EnsemblMetazoa.
DR   GO; GO:0046426; P:negative regulation of receptor signaling pathway via JAK-STAT; IEA:EnsemblMetazoa.
DR   InterPro; IPR036236; Znf_C2H2_sf.
DR   InterPro; IPR013087; Znf_C2H2_type.
DR   Pfam; PF00096; zf-C2H2; 1.
DR   SMART; SM00355; ZnF_C2H2; 3.
DR   SUPFAM; SSF57667; SSF57667; 1.
DR   PROSITE; PS00028; ZINC_FINGER_C2H2_1; 3.
DR   PROSITE; PS50157; ZINC_FINGER_C2H2_2; 2.
PE   2: Evidence at transcript level;
KW   DNA-binding; Metal-binding; Nucleus; Repeat; Transcription;
KW   Transcription regulation; Zinc; Zinc-finger.
FT   CHAIN           <1..>205
FT                   /note="Probable transcription factor Ken"
FT                   /id="PRO_0000046926"
FT   ZN_FING         106..128
FT                   /note="C2H2-type 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         134..157
FT                   /note="C2H2-type 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   ZN_FING         173..196
FT                   /note="C2H2-type 3"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00042"
FT   NON_TER         1
FT   NON_TER         205
SQ   SEQUENCE   205 AA;  22896 MW;  3183ED683100CAAF CRC64;
     NMLAHLEDGA LNGDTLTPDR KHLLEAQRNR AHSPEMPMHL GPQFVYQWQS NQNAAMSAMP
     NLQSRLSSLS HISLNLDHPE GRSGSASGSA ANLAGSNTHA SSVREYRCEY CGKQFGMSWN
     LKTHLRVHTG EKPFACRLCV AMFKQKAHLL KHLCSVHRNV ITTTNGADTE NRYSCCFCSM
     CFESVQELVR HLSGHHNNLL LTKNL