ID   1106L_ASFK5             Reviewed;         122 AA.
AC   P0C9H8;
DT   05-MAY-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-MAY-2009, sequence version 1.
DT   03-AUG-2022, entry version 17.
DE   RecName: Full=Protein MGF 110-6L;
DE   Flags: Precursor;
GN   OrderedLocusNames=Ken-013;
OS   African swine fever virus (isolate Pig/Kenya/KEN-50/1950) (ASFV).
OC   Viruses; Varidnaviria; Bamfordvirae; Nucleocytoviricota; Pokkesviricetes;
OC   Asfuvirales; Asfarviridae; Asfivirus.
OX   NCBI_TaxID=561445;
OH   NCBI_TaxID=6937; Ornithodoros (relapsing fever ticks).
OH   NCBI_TaxID=85517; Phacochoerus aethiopicus (Warthog).
OH   NCBI_TaxID=41426; Phacochoerus africanus (Warthog).
OH   NCBI_TaxID=273792; Potamochoerus larvatus (Bushpig).
OH   NCBI_TaxID=9823; Sus scrofa (Pig).
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Kutish G.F., Rock D.L.;
RT   "African swine fever virus genomes.";
RL   Submitted (MAR-2003) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role in virus cell tropism, and may be required for
CC       efficient virus replication in macrophages. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Host endoplasmic reticulum lumen
CC       {ECO:0000250|UniProtKB:P68744}.
CC   -!- INDUCTION: Expressed in the early phase of the viral replicative cycle.
CC       {ECO:0000305}.
CC   -!- PTM: N-glycosylated. {ECO:0000250|UniProtKB:P68744}.
CC   -!- SIMILARITY: Belongs to the asfivirus MGF 110 family. {ECO:0000305}.
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DR   EMBL; AY261360; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Proteomes; UP000000861; Genome.
DR   GO; GO:0044166; C:host cell endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
DR   InterPro; IPR004848; ASFV_fam_110.
DR   Pfam; PF01639; v110; 1.
DR   PROSITE; PS00014; ER_TARGET; 1.
PE   3: Inferred from homology;
KW   Early protein; Glycoprotein; Host endoplasmic reticulum; Signal.
FT   SIGNAL          1..18
FT                   /evidence="ECO:0000255"
FT   CHAIN           19..122
FT                   /note="Protein MGF 110-6L"
FT                   /id="PRO_0000373200"
FT   MOTIF           119..122
FT                   /note="Prevents secretion from ER"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU10138"
FT   CARBOHYD        100
FT                   /note="N-linked (GlcNAc...) asparagine; by host"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   122 AA;  14367 MW;  49B38E9742B3E3E7 CRC64;
     MLVIFLGILG LMASQVLGLP SNQPTGQLRP TEDPPEEELE YWCAYMESCQ FCWDCQDGNC
     INKIDGSVIY KNEFVRPCSV SRWMDKCMYD LNKGIYHTMN CSQPQSWNPY KYFRKEWKKD
     EL