KHPB_ALKHC
ID KHPB_ALKHC Reviewed; 207 AA.
AC Q9RCA6;
DT 01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 104.
DE RecName: Full=RNA-binding protein KhpB {ECO:0000255|HAMAP-Rule:MF_00867};
DE AltName: Full=RNA-binding protein EloR {ECO:0000255|HAMAP-Rule:MF_00867};
GN Name=khpB {ECO:0000255|HAMAP-Rule:MF_00867};
GN Synonyms=eloR {ECO:0000255|HAMAP-Rule:MF_00867},
GN jag {ECO:0000303|PubMed:10427704}; OrderedLocusNames=BH4063;
OS Alkalihalobacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344
OS / JCM 9153 / C-125) (Bacillus halodurans).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Alkalihalobacillus.
OX NCBI_TaxID=272558;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125;
RX PubMed=10427704; DOI=10.1271/bbb.63.1134;
RA Takami H., Masui N., Nakasone K., Horikoshi K.;
RT "Replication origin region of the chromosome of alkaliphilic Bacillus
RT halodurans C-125.";
RL Biosci. Biotechnol. Biochem. 63:1134-1137(1999).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125;
RX PubMed=11058132; DOI=10.1093/nar/28.21.4317;
RA Takami H., Nakasone K., Takaki Y., Maeno G., Sasaki R., Masui N., Fuji F.,
RA Hirama C., Nakamura Y., Ogasawara N., Kuhara S., Horikoshi K.;
RT "Complete genome sequence of the alkaliphilic bacterium Bacillus halodurans
RT and genomic sequence comparison with Bacillus subtilis.";
RL Nucleic Acids Res. 28:4317-4331(2000).
CC -!- FUNCTION: A probable RNA chaperone. Forms a complex with KhpA which
CC binds to cellular RNA and controls its expression. Plays a role in
CC peptidoglycan (PG) homeostasis and cell length regulation.
CC {ECO:0000255|HAMAP-Rule:MF_00867}.
CC -!- SUBUNIT: Forms a complex with KhpA. {ECO:0000255|HAMAP-Rule:MF_00867}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00867}.
CC -!- DOMAIN: Has an N-terminal Jag-N domain and 2 RNA-binding domains (KH
CC and R3H). {ECO:0000255|HAMAP-Rule:MF_00867}.
CC -!- SIMILARITY: Belongs to the KhpB RNA-binding protein family.
CC {ECO:0000255|HAMAP-Rule:MF_00867}.
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DR EMBL; AB013492; BAA82681.1; -; Genomic_DNA.
DR EMBL; BA000004; BAB07782.1; -; Genomic_DNA.
DR PIR; G84157; G84157.
DR RefSeq; WP_010900187.1; NC_002570.2.
DR AlphaFoldDB; Q9RCA6; -.
DR SMR; Q9RCA6; -.
DR STRING; 272558.10176688; -.
DR EnsemblBacteria; BAB07782; BAB07782; BAB07782.
DR KEGG; bha:BH4063; -.
DR eggNOG; COG1847; Bacteria.
DR HOGENOM; CLU_042512_0_1_9; -.
DR OMA; MLDIASW; -.
DR OrthoDB; 1304273at2; -.
DR Proteomes; UP000001258; Chromosome.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR GO; GO:0071555; P:cell wall organization; IEA:UniProtKB-KW.
DR GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR CDD; cd02414; jag_KH; 1.
DR CDD; cd02644; R3H_jag; 1.
DR Gene3D; 3.30.1370.50; -; 1.
DR Gene3D; 3.30.30.80; -; 1.
DR Gene3D; 3.30.300.20; -; 1.
DR HAMAP; MF_00867; KhpB; 1.
DR InterPro; IPR038008; Jag_KH.
DR InterPro; IPR038247; Jag_N_dom_sf.
DR InterPro; IPR015946; KH_dom-like_a/b.
DR InterPro; IPR039247; KhpB.
DR InterPro; IPR032782; KhpB_N.
DR InterPro; IPR001374; R3H_dom.
DR InterPro; IPR036867; R3H_dom_sf.
DR InterPro; IPR034079; R3H_KhpB.
DR PANTHER; PTHR35800; PTHR35800; 1.
DR Pfam; PF14804; Jag_N; 1.
DR Pfam; PF01424; R3H; 1.
DR SMART; SM01245; Jag_N; 1.
DR SMART; SM00393; R3H; 1.
DR SUPFAM; SSF82708; SSF82708; 1.
DR PROSITE; PS51061; R3H; 1.
PE 3: Inferred from homology;
KW Cell shape; Cell wall biogenesis/degradation; Chaperone; Cytoplasm;
KW Reference proteome; RNA-binding.
FT CHAIN 1..207
FT /note="RNA-binding protein KhpB"
FT /id="PRO_0000084278"
FT DOMAIN 58..136
FT /note="KH"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00867"
FT DOMAIN 141..207
FT /note="R3H"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00867"
FT REGION 5..55
FT /note="Jag_N domain"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_00867"
SQ SEQUENCE 207 AA; 23131 MW; BE02AF774460A632 CRC64;
MTKRRVSGKT VEEAVEQAII ELGTTRERIT YTVVEEPKSG LFGILGSKPA VIEVVVKPDP
VDRAKAFLEE LLQEMDMEVE VTIEKDPATV LFNISGEQDL GTLIGKRGQT LDSLQYLVNL
VANKEEGEFI RIKLDAENYR ARRKEALVQL AERLASKALR TKRPVSLEPM SAHERKIIHT
ALQELGDVET YSEGQGIGRH VVIAPKR
