ID   KHR1_YEASX              Reviewed;         296 AA.
AC   P22313;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Killer toxin KHR;
DE   AltName: Full=Killer of heat resistant;
DE   Flags: Precursor;
GN   Name=KHR1; Synonyms=KHR;
OS   Saccharomyces cerevisiae (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=4932;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=18 rho(-);
RX   PubMed=1368554; DOI=10.1271/bbb1961.54.979;
RA   Goto K., Iwatuki Y., Kitano K., Obata T., Hara S.;
RT   "Cloning and nucleotide sequence of the KHR killer gene of Saccharomyces
RT   cerevisiae.";
RL   Agric. Biol. Chem. 54:979-984(1990).
CC   -!- FUNCTION: Kills sensitive strains of yeast.
CC   -!- SIMILARITY: To yeast YER076C. {ECO:0000305}.
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DR   EMBL; D00905; BAA00751.1; -; Genomic_DNA.
DR   PIR; JT0548; JT0548.
DR   AlphaFoldDB; P22313; -.
DR   SGD; S000029237; KHR1.
DR   VEuPathDB; FungiDB:YER076C; -.
DR   GO; GO:0090729; F:toxin activity; IEA:UniProtKB-KW.
PE   3: Inferred from homology;
KW   Glycoprotein; Signal; Toxin.
FT   SIGNAL          1..20
FT                   /evidence="ECO:0000255"
FT   CHAIN           21..296
FT                   /note="Killer toxin KHR"
FT                   /id="PRO_0000021541"
FT   CARBOHYD        46
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        71
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        122
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
FT   CARBOHYD        146
FT                   /note="N-linked (GlcNAc...) asparagine"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   296 AA;  32782 MW;  965AD10BA9CDBF01 CRC64;
     MGHLAILFSI IAVLNIATAV ASSDSIYLKG HRVGQDIDSL YRVYDNGTMY PVTFNEWLND
     LTGMNDLATN NATILKRDSS DVSCVTETCQ YVDYHVDDEG VITIDISTYR IPVEWDSGSA
     GNASYGVSKR DTKYETFCKK KICGINVSGF CNAYDFAVHA FDFGGSVYNP VSGITDRIKE
     ATKRDKTECL GYELDHVRID PAVDWSISIS TWKQGSANCD TQASADSLKC AAQKALESEH
     NHQKTAFCIH LDNGGSFNLD IRLISELSFS KYNPWALPCP KYKGSNSWQV VSDCFQ