ID   ARAB1_STAS1             Reviewed;         538 AA.
AC   Q49ZR6;
DT   22-NOV-2005, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Ribulokinase 1 {ECO:0000255|HAMAP-Rule:MF_00520};
DE            EC=2.7.1.16 {ECO:0000255|HAMAP-Rule:MF_00520};
GN   Name=araB1 {ECO:0000255|HAMAP-Rule:MF_00520}; OrderedLocusNames=SSP0563;
OS   Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM
OS   20229 / NCIMB 8711 / NCTC 7292 / S-41).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Staphylococcaceae;
OC   Staphylococcus.
OX   NCBI_TaxID=342451;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15305 / DSM 20229 / NCIMB 8711 / NCTC 7292 / S-41;
RX   PubMed=16135568; DOI=10.1073/pnas.0502950102;
RA   Kuroda M., Yamashita A., Hirakawa H., Kumano M., Morikawa K., Higashide M.,
RA   Maruyama A., Inose Y., Matoba K., Toh H., Kuhara S., Hattori M., Ohta T.;
RT   "Whole genome sequence of Staphylococcus saprophyticus reveals the
RT   pathogenesis of uncomplicated urinary tract infection.";
RL   Proc. Natl. Acad. Sci. U.S.A. 102:13272-13277(2005).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + D-ribulose = ADP + D-ribulose 5-phosphate + H(+);
CC         Xref=Rhea:RHEA:17601, ChEBI:CHEBI:15378, ChEBI:CHEBI:17173,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58121, ChEBI:CHEBI:456216;
CC         EC=2.7.1.16; Evidence={ECO:0000255|HAMAP-Rule:MF_00520};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + L-ribulose = ADP + H(+) + L-ribulose 5-phosphate;
CC         Xref=Rhea:RHEA:22072, ChEBI:CHEBI:15378, ChEBI:CHEBI:16880,
CC         ChEBI:CHEBI:30616, ChEBI:CHEBI:58226, ChEBI:CHEBI:456216;
CC         EC=2.7.1.16; Evidence={ECO:0000255|HAMAP-Rule:MF_00520};
CC   -!- PATHWAY: Carbohydrate degradation; L-arabinose degradation via L-
CC       ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route):
CC       step 2/3. {ECO:0000255|HAMAP-Rule:MF_00520}.
CC   -!- SIMILARITY: Belongs to the ribulokinase family. {ECO:0000255|HAMAP-
CC       Rule:MF_00520}.
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DR   EMBL; AP008934; BAE17708.1; -; Genomic_DNA.
DR   RefSeq; WP_011302511.1; NZ_MTGA01000036.1.
DR   AlphaFoldDB; Q49ZR6; -.
DR   SMR; Q49ZR6; -.
DR   STRING; 342451.SSP0563; -.
DR   EnsemblBacteria; BAE17708; BAE17708; SSP0563.
DR   KEGG; ssp:SSP0563; -.
DR   PATRIC; fig|342451.11.peg.568; -.
DR   eggNOG; COG1069; Bacteria.
DR   HOGENOM; CLU_009281_9_1_9; -.
DR   OMA; RPRENHA; -.
DR   OrthoDB; 1619686at2; -.
DR   UniPathway; UPA00145; UER00566.
DR   Proteomes; UP000006371; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0019150; F:D-ribulokinase activity; IEA:RHEA.
DR   GO; GO:0008741; F:ribulokinase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0019569; P:L-arabinose catabolic process to xylulose 5-phosphate; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00520; Ribulokinase; 1.
DR   InterPro; IPR043129; ATPase_NBD.
DR   InterPro; IPR000577; Carb_kinase_FGGY.
DR   InterPro; IPR018485; Carb_kinase_FGGY_C.
DR   InterPro; IPR018484; Carb_kinase_FGGY_N.
DR   InterPro; IPR005929; Ribulokinase.
DR   Pfam; PF02782; FGGY_C; 1.
DR   Pfam; PF00370; FGGY_N; 1.
DR   PIRSF; PIRSF000538; GlpK; 1.
DR   SUPFAM; SSF53067; SSF53067; 2.
PE   3: Inferred from homology;
KW   Arabinose catabolism; ATP-binding; Carbohydrate metabolism; Kinase;
KW   Nucleotide-binding; Reference proteome; Transferase.
FT   CHAIN           1..538
FT                   /note="Ribulokinase 1"
FT                   /id="PRO_0000198374"
SQ   SEQUENCE   538 AA;  59629 MW;  FBEE912A62822250 CRC64;
     MTYSIGIDYG TASGRVFLVD TTNGEIISTY IKEYPHGTIS ESLNGTELPH NYFLQHAADY
     TSILEEGVQY VLKDSQVDPK SIIGIGIDFT SCTIVFLDDD FKPLHLHPDL EDQPHAYVKL
     WKHHGAQDEA TYMKQVSDKV NPSWLNFYGH NVNSEWMIPK ILEVKNKAPE VLERSAYIME
     AGDYLVSLLT DKNIRSNCGI GFKGFYNETD GFNYSFFEAI DQELPEIVKT KCESPVVNIG
     ESAGSLSPYY QNLWGLTEQV QISPYIIDAH SGVLGVGAIE QGEFTPVIGT STCHLMLDPK
     QEPIPAITGS VKDAIIPGLY AYEAGQAAVG DLFNYSASLA PKSYVDQAEK QGLSILGYLE
     KLAADISIDK QHVTVLDWHN GNRSILSDSK LTGSIFGLTL QTPFEMIHKA YLESTAFGTK
     MIMQQFENNH IPVETVYAAG GIPIKSELLV DIYANVLNKE VVVIDSSNAT ALGAAMLGAN
     VGGAYPTLKE TVKHMKQPVY YRKQPEAKKV KQYALLFDRY KALHDLLGKE YPQLSYIN