ARAB_GEOKA
ID ARAB_GEOKA Reviewed; 564 AA.
AC Q5KYP6;
DT 12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-2005, sequence version 1.
DT 25-MAY-2022, entry version 80.
DE RecName: Full=Ribulokinase {ECO:0000255|HAMAP-Rule:MF_00520};
DE EC=2.7.1.16 {ECO:0000255|HAMAP-Rule:MF_00520};
GN Name=araB {ECO:0000255|HAMAP-Rule:MF_00520}; OrderedLocusNames=GK1905;
OS Geobacillus kaustophilus (strain HTA426).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC Geobacillus thermoleovorans group.
OX NCBI_TaxID=235909;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=HTA426;
RX PubMed=15576355; DOI=10.1093/nar/gkh970;
RA Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H.,
RA Matsui S., Uchiyama I.;
RT "Thermoadaptation trait revealed by the genome sequence of thermophilic
RT Geobacillus kaustophilus.";
RL Nucleic Acids Res. 32:6292-6303(2004).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-ribulose = ADP + D-ribulose 5-phosphate + H(+);
CC Xref=Rhea:RHEA:17601, ChEBI:CHEBI:15378, ChEBI:CHEBI:17173,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58121, ChEBI:CHEBI:456216;
CC EC=2.7.1.16; Evidence={ECO:0000255|HAMAP-Rule:MF_00520};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-ribulose = ADP + H(+) + L-ribulose 5-phosphate;
CC Xref=Rhea:RHEA:22072, ChEBI:CHEBI:15378, ChEBI:CHEBI:16880,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:58226, ChEBI:CHEBI:456216;
CC EC=2.7.1.16; Evidence={ECO:0000255|HAMAP-Rule:MF_00520};
CC -!- PATHWAY: Carbohydrate degradation; L-arabinose degradation via L-
CC ribulose; D-xylulose 5-phosphate from L-arabinose (bacterial route):
CC step 2/3. {ECO:0000255|HAMAP-Rule:MF_00520}.
CC -!- SIMILARITY: Belongs to the ribulokinase family. {ECO:0000255|HAMAP-
CC Rule:MF_00520}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; BA000043; BAD76190.1; -; Genomic_DNA.
DR RefSeq; WP_011231394.1; NC_006510.1.
DR AlphaFoldDB; Q5KYP6; -.
DR SMR; Q5KYP6; -.
DR STRING; 235909.GK1905; -.
DR EnsemblBacteria; BAD76190; BAD76190; GK1905.
DR KEGG; gka:GK1905; -.
DR eggNOG; COG1069; Bacteria.
DR HOGENOM; CLU_009281_9_1_9; -.
DR OMA; GHKAMWH; -.
DR UniPathway; UPA00145; UER00566.
DR Proteomes; UP000001172; Chromosome.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019150; F:D-ribulokinase activity; IEA:RHEA.
DR GO; GO:0008741; F:ribulokinase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0019569; P:L-arabinose catabolic process to xylulose 5-phosphate; IEA:UniProtKB-UniRule.
DR CDD; cd07781; FGGY_RBK; 1.
DR HAMAP; MF_00520; Ribulokinase; 1.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000577; Carb_kinase_FGGY.
DR InterPro; IPR018485; Carb_kinase_FGGY_C.
DR InterPro; IPR018484; Carb_kinase_FGGY_N.
DR InterPro; IPR005929; Ribulokinase.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR PIRSF; PIRSF000538; GlpK; 1.
DR SUPFAM; SSF53067; SSF53067; 2.
DR TIGRFAMs; TIGR01234; L-ribulokinase; 1.
PE 3: Inferred from homology;
KW Arabinose catabolism; ATP-binding; Carbohydrate metabolism; Kinase;
KW Nucleotide-binding; Reference proteome; Transferase.
FT CHAIN 1..564
FT /note="Ribulokinase"
FT /id="PRO_0000263402"
SQ SEQUENCE 564 AA; 62026 MW; 37109C1971502AC4 CRC64;
MGKKYVIGID YGTESGRAVL VDLEGNEIAD HVTPYPHGVI DEVLPESNVQ LEPDWALQHP
ADYIEVLATA VPTVLQKSGV NPADVIGVGI DFTSCTMLPV DASGEPLCLK PEFRNRPHSW
VKLWKHHAAQ DEANLLNEIA AKRGEAFLPR YGGKISSEWM IAKIWQILNE DPEIYEQTDL
FLEATDWVIF KMTGNIVRNS CAAGYKSIWH KQDGYPSKEF FRALDPRLEH LTETKLRGPI
VPLGTRAGVL TNEMAAMMGL LPGTAVAVGN VDAHAAVPGV GVVEPGKLVM AMGTSICHML
LGTEEKYVEG MCGVVEDGII PGYFGYEAGQ SAVGDIFAWY VEQGVPAYVK EAAEKEGVSV
HEWLEKRAAA YRPGETGLLA LDWWNGNRSV LVDTDLTGLI VGYTLLTKPE EIYRALLEAT
AFGTRKIIDA FVENGVKVDE LYACGGLPQK NKLLMQIYAD VTNREIKIAA SKQTPAVGAA
MFAAVAAGKE NGGYESIVEA ARNMGKVREE TFKPIPENVA MYEQLYQEYT KLHDYFGRGE
NDVMKRLKHW KETARAAKES MTLS
